Approaches for portably and discreetly treating muscle cramping using one or more of a selectively controllable transcutaneous electrical nerve stimulation (TENS) unit and a heating element comprising resistive fabric. Cramping of the muscle may be detected with a surface electromyography (sEMG) unit. Artificial intelligence techniques may be applied using the sEMG signals and/or user input to identify effective treatment settings.

A device for stimulating neurons that includes a stimulation unit that applies mechanically tactile and/or thermal stimuli to the body surface of a patient that stimulate neurons with a pathologically synchronous and oscillatory neural activity. The device includes a measuring unit that records measurement signals of neural activity of the stimulated neurons, and a controller that controls the stimulation unit and analyzes the measurement signals. The controller actuates the stimulation unit to scan at least one part of the body surface of the patient along a path and thereby periodically applies stimuli and also selects two regions or more regions on the patient's body surface along the path where the phase synchronization between the periodic application of the stimuli and the neural activity of the stimulated neurons have a local maximum using the measurement signals. The stimuli are then applied in a delayed manner in the two regions.

A device comprising a heat-generating component that comprises an alkali metal is provided. The alkali metal in the presence of water at a point of contact of the device undergoes an exothermic reaction to generate heat in situ. The amount of heat generated is proportional to and/or limited by the amount (or moles) of water at the point of contact, and the heat generated is sufficient to achieve an increase in temperature at the point of contact to achieve a therapeutic or beneficial result. In one embodiment, the device is used for reducing sweat production in a subject suffering from excessive sweating or hyperhidrosis. In other embodiments, the device is used to substantially sterilize a surface or render a surface substantially aseptic.

A heating device includes a heating unit and device electronics. The heating unit is configured to deliver heat to a user's body. The heating unit includes a substrate and a heating element supported by the substrate. The device electronics are coupled to the heating element and are configured to store a first heating profile that includes data indicating how power should be delivered to the heating element over a first period of time. The device electronics are configured to deliver power to the heating element according to the first heating profile. The device electronics are configured to wirelessly receive a second heating profile from an external computing device. The second heating profile includes data indicating how power should be delivered to the heating element over a second period of time. The device electronics are configured to deliver power to the heating element according to the second heating profile.

A reinforcing clinical wrap is provided with integral thermal management. The clinical wrap includes a fluid circuit for a heat transfer medium to circulate between a fluid inlet and a fluid outlet. A shape conforming medium is disposed within a portion of the clinical wrap providing selective reinforcement support of the portion of the clinical wrap to conform to a surface of a patient. Non-limiting examples of the shape conforming medium may include a magnetorheological elastomer, a magnetorheological elastomer, a magnetorheological foam, a UV curable resin, and a phase change material.

Thermal therapy systems, devices, and methods of using the same disclosed. A localized hypothermia of the pancreas with a delivery and placement procedure in the stomach of a patient comprising a cooling balloon system is disclosed that can be used for the treatment of pancreatitis in a patient. The cooling balloon system can have mechanisms for affecting the pancreas without impacting or inducing hypothermia in the patient in a systemic fashion. The localized hypothermia system can have a simplified delivery system and can be intended to reduce patient discomfort while reducing the metabolic activity of the inflamed pancreas of the patient.

Thermal therapy systems, devices, and methods of using the same disclosed. A localized hypothermia of the pancreas with a delivery and placement procedure in the stomach of a patient comprising a cooling balloon system is disclosed that can be used for the treatment of pancreatitis in a patient. The cooling balloon system can have mechanisms for affecting the pancreas without impacting or inducing hypothermia in the patient in a systemic fashion. The localized hypothermia system can have a simplified delivery system and can be intended to reduce patient discomfort while reducing the metabolic activity of the inflamed pancreas of the patient.

An automated therapy system having an infusion catheter; a sensor adapted to sense a patient parameter; and a controller communicating with the sensor and programmed to control flow output from the infusion catheter into a patient based on the patient parameter without removing fluid from the patient. The invention also includes a method of controlling infusion of a fluid to a patient. The method includes the following steps: monitoring a patient parameter with a sensor to generate a sensor signal; providing the sensor signal to a controller; and adjusting fluid flow to the patient based on the sensor signal without removing fluid from the patient.

A reinforcing clinical wrap is provided with integral thermal management. The clinical wrap includes a fluid circuit for a heat transfer medium to circulate between a fluid inlet and a fluid outlet. A shape conforming medium is disposed within a portion of the clinical wrap providing selective reinforcement support of the portion of the clinical wrap to conform to a surface of a patient. Non-limiting examples of the shape conforming medium may include a magnetorheological elastomer, a magnetorheological elastomer, a magnetorheological foam, a UV curable resin, and a phase change material.

Systems and methods for treating a body region are provided herein. A treatment device for treating a body region is provided, and may include a first applicator and a second applicator. The first and second applicators are held on the body region by a belt. The first applicator may include a first magnetic field generating device and a radiofrequency electrode. The second applicator may include a second magnetic field generating device. The first and second magnetic field generating devices may each generate a time-vary magnetic field with a plurality of sequential magnetic impulses to cause muscle contraction in the body region. The radiofrequency electrode may provide radiofrequency waves causing heating of tissue within the body region. The treatment device may further include an energy storage device and a switching device. The switching device my discharge energy from the energy storage device to the first or the second magnetic field generating device to generate the time-vary magnetic field.