A shoe includes a sole including front and rear compartments; a warming device in the front compartment; a main battery and circuit board in the rear compartment and enclosed by a first insulation member; a switch on a heel cap of the shoe; a display member on the heel cap a light emitting member on the heel cap; and an auxiliary battery enclosed by a second enclosure in the heel cap. The main battery and circuit board is electrically connected to the warming device, the push-button switch, the light emitting member, and the auxiliary battery respectively.

Presenting a new approach to architect footwear as a communication and energy-transporting platform for personalized smart living. This is done by integrating the most advanced technologies today, along with some known technologies still under development, to provide solutions to power on demand for all personal and wearable devices.

The systems, methods, and apparatuses disclosed in this invention make our personal and wearable devices smarter, thereby providing higher practical functions and more efficiency to our everyday lives.

A device comprising a heat-generating component that comprises an alkali metal is provided. The alkali metal in the presence of water at a point of contact of the device undergoes an exothermic reaction to generate heat in situ. The amount of heat generated is proportional to and/or limited by the amount (or moles) of water at the point of contact, and the heat generated is sufficient to achieve an increase in temperature at the point of contact to achieve a therapeutic or beneficial result. In one embodiment, the device is used for reducing sweat production in a subject suffering from excessive sweating or hyperhidrosis. In other embodiments, the device is used to substantially sterilize a surface or render a surface substantially aseptic.

Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described as well as for providing for other treatments. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance of cellulite. Treatments can include cooling a surface of a patient's skin and detecting at least one freeze event in the cooled skin. The treatment system can continue cooling the patient's skin after the freeze event(s) are detected so to maintain at least a partially frozen state of the tissue for a period of time.

A device comprising a heat-generating component that comprises an alkali metal is provided. The alkali metal in the presence of water at a point of contact of the device undergoes an exothermic reaction to generate heat in situ. The amount of heat generated is proportional to and/or limited by the amount (or moles) of water at the point of contact, and the heat generated is sufficient to achieve an increase in temperature at the point of contact to achieve a therapeutic or beneficial result. In one embodiment, the device is used for reducing sweat production in a subject suffering from excessive sweating or hyperhidrosis. In other embodiments, the device is used to substantially sterilize a surface or render a surface substantially aseptic.

Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.

A therapeutic apparatus for treating damaged tissue on a limb or body of a subject includes a wearable adapted to cover and be secured to the limb or body of a subject over damaged tissue. The wearable being configured to reduce pressure on the damaged tissue and adapted to deliver one or more treatments selected from the group consisting of heat, oxygen, electrical current, and light to the damaged tissue.

Treatment systems, methods, and apparatuses for treating acne, hyperhidrosis, and other skin conditions are described. Aspects of the technology can include cooling a surface of a patient's skin and detecting changes in the tissue. The tissue can be cooled a sufficient length of time and to a temperature low enough to affect glands or other targeted structures in the skin.

A means can be used instead of or with conventional temperature control to achieve warming device temperature control at a lower cost, prevent or reduce deterioration of a warming device over time, and lower generated heat temperature due to storage at high temperatures. The warming device can be used for the same. A higher level temperature control means can be used for warming devices for medical applications. An improved warming device can be used for medical applications with a high level of safety and efficacy. A temperature control agent controls a maximum temperature of a warming device with a heat generating composition that generates heat by reaction with oxygen. Said agent includes an aliphatic compound that has a particle form that will not pass through a standard sieve with a #60 mesh, a melting point of 35-65 C., and an aqueous solubility (g/100 mL) at 20 C. of 5.

Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described as well as for providing for other treatments. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance of cellulite. Treatments can include cooling a surface of a patient's skin and detecting at least one freeze event in the cooled skin. The treatment system can continue cooling the patient's skin after the freeze event(s) are detected so to maintain at least a partially frozen state of the tissue for a period of time.