Muscles held under tension undergo a chemical reaction that generates heat within the muscle, and subsequently that heat contributes to muscle fatigue. Research in the field of physiology and sports medicine has demonstrated that actively cooling an athlete's core body temperature can rapidly rejuvenate a fatigued muscle thereby allowing the athlete to extend the muscle's potential. Mammalians have several areas of glabrous tissue wherein a dense network of veins near the surface of the skin act as heat exchangers for cooling and regulating their core temperature. The process for effective cooling via glabrous tissue is optimized within a narrow range of temperatures. Presented herein is a handheld cooling device which is optimized for the efficient transfer of heat away from the fatigued muscles via direct contact with glabrous tissue.

Systems and methods for improving or preventing a condition, such as the treatment of pain syndromes and migraine headaches are disclosed. A method for treating pain can include one or more of the steps including identifying a region of the patient comprising glabrous tissue; positioning the region of the patient comprising glabrous tissue into an enclosed chamber; adjusting the relative humidity of the enclosed chamber sufficient to create a physiologic effect. The method need not involve altering the temperature within the enclosed chamber.

A catheter assembly includes an elongate catheter body defining a longitudinal axis, and a plurality of cooling needles configured to be extended from the catheter body to penetrate a vessel wall of a vessel in which the elongate catheter body is positioned and extend to an ablation region within tissue adjacent the vessel wall. At least one cooling needle of the plurality of cooling needles is further configured to receive a flow of cryogenic fluid to cool the at least one cooling needle.

The invention pertains to an electrically operated cryocabin arrangement (100) comprising an open-top cabin (10) with a number of thermal sensor arrays (13) arranged at different heights along an internal perimeter of the cabin, a number of cooling units (20), and a data processing unit (30), wherein the data processing unit is configured to receive user-specific data comprising at least temperature indications (t1) measureable at skin surface of a user by the thermal sensor arrays throughout an operation cycle, during which cycle a cooling fluid (201) is delivered into the cabin and distributed inside the cabin via the cooling units (20), and, based on said user-specific data, to selectively adjust variables related to distribution of the cooling fluid inside the cabin to a predetermined level, said variables being at least a flow velocity (V) of a cooling fluid stream and/or a temperature (t2) of the cooling fluid, wherein the cooling fluid distribution variables are adjusted to reach the values, at which temperature indications (t1) measureable at the user skin surface are within a range of 0 to +20 degree Celsius, and wherein adjustment is performed in real time, continuously throughout the operation cycle. A computer implemented method to operate the cryocabin arrangement and a computer program product adapted to perform the method are further provided.

A system includes a console and a balloon catheter with an inner balloon and an outer balloon. The console is fluidly coupled to the balloon catheter via aa first vacuum line and and a second vacuum line. The console includes processing circuitry configured to determine whether at least one breach condition is satisfied based on at least one parameter measured by sensors of the system. Responsive to determining that at least one of the breach conditions is satisfied, the processing circuitry is configured to cause, at a first time, passive suction to be exerted on the first vacuum line and active suction to be exerted on the second vacuum line. Additionally, the processing circuitry is configured to cause, at a second time that is after the first time, active suction to be exerted on first vacuum line and the second vacuum line.

A self-contained, hyperthermic conditioning unit and selectively controllable environment for exercising. The unit comprises a base portion having a bed therein and a removable cover connected to the base portion to enclose a personal compartment within the unit. One or more heating elements provide heat to the personal compartment and one more pieces of physical exercise equipment are provided within the personal compartment.

Muscles held under tension undergo a chemical reaction that generates heat within the muscle, and subsequently that heat contributes to muscle fatigue. Research in the field of physiology and sports medicine has demonstrated that actively cooling an athlete's core body temperature can rapidly rejuvenate a fatigued muscle thereby allowing the athlete to extend the muscle's potential. Mammalians have several areas of glabrous tissue wherein a dense network of veins near the surface of the skin act as heat exchangers for cooling and regulating their core temperature. The process for effective cooling via glabrous tissue is optimized within a narrow range of temperatures. Presented herein is a handheld cooling device which is optimized for the efficient transfer of heat away from the fatigued muscles via direct contact with glabrous tissue.

A heat exchange system includes a thermoelectric device operably coupled with a support apparatus. The thermoelectric device is configured to reduce a temperature at a first location and increase a temperature at a second location different than the first location. A fan is disposed adjacent to the thermoelectric device. The fan is configured to direct heat generated by the thermoelectric device toward the second location. A controller is communicatively coupled with the thermoelectric device and the fan. The controller is configured to activate the thermoelectric device and the fan to reduce the temperature at the first location and concurrently increase the temperature at the second location. The first location is configured to align with a first area on a patient and the second location is configured to align with a second area on the patient.