Provided herein are methods of nerve blockage, for example for treatment of obesity, heart failure, cardiovascular disease, muscle spasms, chronic pain, or urinary retention in a patient. The method comprises first heating a nerve above physiological temperature (e.g., 37 C. in a human), such as from 43 C. to 54 C. for a duration that leads to reversible nerve blockage as opposed to nerve damage. Second, reversible nerve blockage is produced by cooling the nerve below physiological temperature to a temperature in which reversible nerve blockage is achieved, for example from 15 C. to 30 C.

A heating pad assembly includes a flexible heating pad having a flexible substrate forming a plurality of deflectable tabs and one or more electrically conductive heating traces routed through the plurality of deflectable tabs and configured to radiate heat therefrom in response to electrical current flowing through the one or more heating traces.

The invention relates a device for the hyperthermal treatment of a herpes disease on a skin, preferably a lip, wherein a control device is configured to regulate a treatment surface on an outer side facing the skin by heating at least one heating element in a heating phase to a contact temperature of 43-47 C. during a contact of the treatment surface with the skin, preferably the lip, and to maintain the contact temperature in a treatment phase for a time period between 1 and 10 seconds.

Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system is included having an electric field generating circuit configured to generate one or more electric fields and a control circuit in communication with the electric field generating circuit. The control circuit configured to control delivery of the one or more electric fields from the electric field generating circuit. The system can include two or more electrodes to deliver the electric fields to a site of a cancerous tumor within a patient and a temperature sensor to measure the temperature of tissue at the site of the cancerous tumor. The control circuit can cause the electric field generating circuit to generate one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz. Other embodiments are also included herein.