A dry eye treatment device, comprising a roller, a holder, wherein the roller contacts and rolls over an eyelid in a plurality of directions in a treatment; a heating element to generate heat, wherein at least a portion of the heat is transferred to the roller; a temperature monitoring system, which comprises a thermal sensor and a temperature control circuit; and an electric power source. The roller is of a convex cylindrical or concave cylindrical shape. A method for dry eye treatment, comprising: cleaning an eyelid with a first cleansing wipe; heating a roller to a predetermined temperature; applying thermally conductive gel between the roller and the eyelid; rolling the roller over the eyelid in a plurality of directions; and removing the thermally conductive gel and expressed debris with a second cleansing wipe; and further, increasing the temperature by an increment and repeating the treatment method.

A method and system in accordance with a particular embodiments of the technology includes applying a substance onto skin of a human subject. A subject's skin can be altered to facilitate absorption of applied substances. A substance can be applied to altered skin so that the substance is absorbed into the skin. The treatment site can be cooled to initiate a freeze event in the skin to freeze tissue. The substance can be a coupling media that promotes or inhibits freezing of tissue.

A method and system in accordance with a particular embodiments of the technology includes applying a substance onto skin of a human subject. An applicator is then applied to the subject to cool a region of the subject. After cooling the tissue, a nucleation initiator is used to initiate a freeze event in the tissue. The nucleation initiator can be an ice crystal that inoculates the skin upon contact to create a predictable freeze event therein. The time of contact between the ice crystal and the skin can be controlled to achieve desired effects.

A method and system in accordance with particular embodiments includes applying a substance onto skin of a human subject. A method for treating a subject's skin includes applying a hydrogel to the skin which contains the substance. The hydrogel and the skin are cooled using a cooling applicator to treat tissue via the cooling treatment by either freezing or not freezing tissue.

A method and system in accordance with a particular embodiments of the technology includes applying a substance onto skin of a human subject. The applied substance can include a freezing point depressant and a liposome, an oil-in-water emulsion, a water-in-oil emulsion, or an oil-in-oil emulsion and can be configured to protect or target tissue. The substance and a surface of the skin can be cooled using the applicator to treat acne and other skin conditions.

A respiration-based body temperature modifying apparatus including an air temperature modifying element producing temperature-altered air and a respiration zone that, in use, communicates with the respiratory system of the user and receives the temperature-altered air so that the user can draw the temperature-altered air from the respiration zone into the lungs to alter body temperature.

Disclosed herein are targeted temperature management (“TTM”) systems, pads, and methods thereof for treating burn wounds. A method of a system for TTM can include a pad-connecting step, a pad-placing step, and a fluid-circulating step. The pad-connecting step can include connecting an inlet and an outlet of a pad to a hydraulic system of a control module. The pad can include a multilayered pad body having a conduit layer configured to convey a temperature-controlled fluid provided by the control module. The pad-placing step can include placing the pad on a wounded portion of a patient's body with a sterile, thermally conductive wound-healing layer of the pad body in contact with a burn wound of the wounded portion of the patient's body. The fluid-circulating step can include circulating the temperature-controlled fluid through the conduit layer to cool the wounded portion of the patient's body, thereby treating the wound to promote healing.

A device includes light sources, electromagnetic field generators, and vibration components to apply a variety of treatment regimens to a living animal organism, including a human person or a body part of a person. The light and electromagnetic therapy are applied at frequencies which have physiological effects, and which can be combined to induce lipolysis, stimulate muscle, and achieve other effects. Feedback is used to dynamically adjust the intensity, duration, and other parameters of the light, electromagnetic, and vibration treatment modalities.

A temperature regulating socket apparatus for selectively heating or cooling a residual limb of an amputee is provided. The temperature regulating socket apparatus includes a socket having a brim, a distal end and a continuous side wall, all defining an open interior area for receiving the residual limb therein and a temperature regulating apparatus. The temperature regulating apparatus includes a thermal adjustment element embedded within the socket side wall; a temperature control unit operatively coupled to the thermal adjustment element; and a power supply operatively coupled to the temperature control unit. When the power supply is in its ON orientation the temperature control unit is powered so that the temperature control unit regulates the temperature of the thermal adjustment element to selectively heat or cool the residual limb within the socket.

A method and apparatus for manipulating a temperature set-point of a human or homeothermic-animal for increasing or decreasing the body temperature above or below the prevailing body temperature for therapeutic purposes. The method includes the steps of warming or cooling sphenoid sinuses externally resulting in manipulation of the temperature of the pituitary gland which in turn results in manipulation of the body-temperature set-point and the body temperature manipulates accordingly to the new temperature set-point. A heat exchange medium can be used to warm or cool sphenoid sinuses and thus the pituitary gland. The heat exchange fluid can be liquid, or gas maintained at a predetermined temperature. Alternatively, a temperature-controlled probe can be used that upon contact with the sphenoid sinuses provides for the heat exchange.