A plurality of methods and apparatus for managing deficiencies of the meibomian gland lipid production and delivery, including wearable fabrics configured with a matrix of micro- and nano-electromechanical materials, or composite fibres of yarn that are substantially made from carbon nanotubes, graphene, spider silk, natural silk, denim, cotton, metals, or combination thereof. Other methods and apparatus include infrared and ultrasound energy sources within a kit aimed at personalised therapies for improving overall health of the eyelids, while providing for adjunctive relief for associated dry eye symptoms. The management kit may comprise a wearable fabric or spectacle frame configured with infrared emitters and sensors, a handheld imaging device and software containing dosage and administration information coupled with information on improving eyelid hygiene which is reviewed and periodically updated using user-specific information.

A pneumatic compression assembly that includes a sleeve having an outer layer and an inner layer that defines a sleeve interior configured to receive a body part of a user, and at least a first vibration assembly configured to provide vibration to the body part of the user. A plurality of inflatable compartments are arranged longitudinally along the sleeve between the inner layer and the outer layer. The first vibration assembly includes a plurality of vibration motors positioned between the inner layer and the outer layer of the sleeve.

A prosthetic socket cooling system and method includes a strap for coupling about a limb fitted with a prosthetic socket. One or more thermally conductive heat spreaders are associated with the strap and may be at least partially seated underneath the prosthetic socket. A heat extraction subsystem is coupled to at least one of the lengthy heat spreaders and carried by the strap. In one version, heat spreaders may form sections of the strap.

A device comprising a housing having a handle end and a treatment end. The treatment end is configured to provide an antimicrobial treatment and a heat treatment. The treatment end comprises an applicator having an applicator surface for providing at least the heat treatment. The device includes a heat generation unit configured to heat the applicator surface in use, a source of antimicrobial agent, and a control unit operatively connected to at least the heat generation unit for controlling the heat generation unit. The device can be a hand-held device and used to apply topical treatment to a treatment area of a subject.

The cooling system (100, 300, 400, 500, 700, 750) includes an applicator (101, 501, 701) configured to hold a predetermined amount of solid coolant and fluid coolant (117) to cool a targeted area of the body (162, 570) to crystalize the lipid-rich cells underneath the targeted area to reduce the fat cells. The applicator may include a thermoelectric cooler (TEC, 136, 704, 706) where the hot side is cooled by coolant held within the applicator. The cold side of the TEC may be thermally coupled to a cooling plate (138, 560) configured to cool a targeted area of the skin at a predetermined temperature range for a predetermined period of time. The cooling system may also be used to relieve localized pain at certain area of the body and/or utilized for cryotherapy.

A knee brace is provided for monitoring the knee. The knee brace includes a dock for removably receiving a control module. The control module is electrically coupled with the dock when the control module is received in the dock. The knee brace includes a sensor for measuring a physiological state of the wearer. The sensor is electrically coupled to the control module by way of the first conductive path when the control module is received in the dock.

A handheld cryoanesthesia or analgesia device for cooling a target area on cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone having an elongated body and a thermoelectric cooling system disposed within the elongated body. The thermoelectric cooling system is configured to physically contact and thermally couple the target area of the cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone to induce cryoanesthesia or analgesia. The thermoelectric cooling system includes a thermally-conductive cold tip, a thermally-conductive cooling power concentrator thermally coupled to the cold tip, at least one Peltier unit module thermally coupled to the cooling power concentrator, a heatsink thermally coupled to at least one Peltier unit module, a power source, at least one thermal sensor, and a controller operably outputting a control signal to the Peltier unit module to maintain a predetermined temperature.

A heat sleeve for selectively heating a residual limb of an amputee is provided. The heat sleeve includes a first sock member having an open proximal end, a distal end and a continuous side wall, all defining an open interior area configured to receive the residual limb therein. A temperature regulating apparatus includes a thermal adjustment element adapted to be mounted onto an exterior surface of the first sock member proximate the distal end, and a power supply operatively coupled to the thermal adjustment element. When the power supply is in its ON orientation and providing power to the thermal adjustment element, the thermal adjustment element selectively heats the residual limb within the first sock. A second sock member may then receive the residual limb, the first sock member and the flexible heating element therein.

A bed sheet heating pad comprises a plurality of control area, each control area comprising a thermal controlling unit, a heating unit, a pressure/temperature sensing unit, a communication unit and a power source, the thermal controlling unit is for receiving control signals from the communication unit to control the heating unit to generate heat, the pressure/temperature sensing unit is for sensing the pressure/temperature of the heating unit and transmitting the sensing signal to the thermal controlling unit to control the temperature of the heating unit, the communication unit is connected to a central control unit and receiving control signal from the central control unit to control the temperature of the control area, and the power source is for supplying the power used in each unit.

An endoscope includes a handle including a handle housing, an irrigation inlet port adapted to receive irrigation fluid, and an irrigation channel; and an insertion cord extending distally from the handle. The insertion cord includes an insertion tube; a bending section extending from the insertion tube; a distal tip extending from the bending section and including a tip housing; a camera at least partially enclosed in the tip housing; interstitial space within the insertion tube in fluid communication with the irrigation channel; and at least one interstitial flow opening in fluid communication with the interstitial space and adapted to discharge the irrigation fluid.