Systems and methods for preparation of an implant and ab interno insertion of the implant into an eye of a patient including a tissue cartridge configured to receive and hold a patch of a material; a cutting device; and a delivery device. Related devices, systems, and methods are provided.

A phacoemulsification tip, including an aspiration tube presenting a cutting tip at a distal end. The aspiration tube has a tube wall presenting an internal face and an external face. The internal face supports at least one internally extending internal ridge. The internal ridge presents an internal distal face, an internal proximal face and an internal apex. The internal distal face meets the internal face at an acute angle measured internally. The internal ridge is structured to engage lens fragments separated from a crystalline lens to enhance proximal movement of the lens fragments and to inhibit distal movement of the lens fragments through the aspiration tube.

A capsulotomy device has a tool holder. The tool holder includes a cutting blade at its distal end and is arranged to move in a distal direction in the device to form an operative state of the device where the cutting blade projects out of a distal end of the capsulotomy device. The at least a portion of the tool holder is adapted in the device's operative state to reciprocate in the distal and proximal directions to urge rotation of the cutting blade.

A surgical knife safety device having a handle, a blade connected to the handle, and a guard carried by the handle for sliding movement between a retracted position in which the blade is exposed for use, and an extended position for covering the sharp cutting edge of the blade. In the retracted position, an enlarged guard radius is provided at the distal end of the handle to allow improved handle control and blade orientation. The enlarged guard radius is positioned to allow the user to firmly grip a large distal handle portion which is preferably molded as a single piece with the blade holder, preventing unwanted blade or handle movement due to guard mechanism tolerances. A spring, such as leaf spring or a cantilever beam, and a pair of detents or slots are provided to fix the guard in the extended or retracted position and to provide resistance during movement between the two positions. Additionally, a pushback prevention mechanism, a user operable lock and a drop-force operable lock are provided to prevent accidental retraction of the guard from the fully extended and guarded position.

Laser assisted cataract surgery methods and devices utilize one or more treatment laser beams to create a shaped opening in the anterior lens capsule of the eye when performing a capsulorrhexis procedure. A light absorbing agent may be applied to the anterior lens capsule to facilitate laser thermal separation of tissue along a treatment beam path on the lens capsule. Relative or absolute reflectance from the eye, and optionally from a surgical contact lens, may be measured to confirm and optionally quantify the presence of the light absorbing agent, before the treatment beam is applied. Such measurements may be used to determine that sufficient light absorbing agent is present in the lens capsule so that transmission of the treatment beam through the capsule will be below a predetermined threshold deemed safe for the retina and other interior portions of the eye, and may also be used to determine that sufficient light absorbing agent is present to result in complete laser thermal separation of the anterior capsule along the treatment beam path. Visualization patterns produced with one or more target laser beams may be projected onto the lens capsule tissue to aid in the capsulorrhexis procedure. In addition or alternatively, virtual visualization patterns may presented on a display integrated with a laser assisted cataract surgery device to aid in the procedure. The visual axis of the eye may be determined, during surgery for example, with a laser beam on which the patient is fixated. The orientation of a toric IOL may be assessed during or after placement by observing the reflection from the back of the eye of a laser beam on which the patient is fixated. The devices disclosed herein may be attached to or integrated with microscopes.

A pneumatic cross-connect proportional valve provides the capability to calibrate pressure and vacuum sensors in a surgical cassette associated with a surgical console. Calibration of non-invasive pressure and vacuum sensors in a cassette by utilizing a proportional cross-connect to pressurize the lines with set pressure or vacuum the lines with set vacuum and measure the response of respective sensors in the cassette. The use of proportional pressure may be used along with other clearing methods to clear material clogging the aspiration channel pathways and tubing of the surgical system. Utilize the cross-connect functionality to more rapidly pressurize the aspiration line upon detection or prediction of a post occlusion surge, thereby reducing the pressure difference between the surgical field, the eye chamber, and aspiration line which may prevent, for example, a surge of fluid out of the anterior chamber of the eye.

A method of performing laser surgery in a patient's eye includes generating a light beam, deflecting the light beam using a scanner to form an enclosed treatment pattern that is configured to form an enclosed capsulorhexis incision that includes a registration feature, and delivering the enclosed treatment pattern to target tissue in the patient's eye to form in an anterior lens capsule of the patient's eye the enclosed capsulorhexis incision that includes the registration feature. The registration feature is configured so that an edge of the target tissue formed by the enclosed capsulorhexis incision mates with an intraocular lens registration feature on an intraocular lens so as to rotationally register the intraocular lens relative to the registration feature.

A patient interface device for use in ophthalmic surgery, which includes a rigid body and a suction ring joined to a lower end of the body, where the suction ring includes an annular skirt made of a soft and flexible material and located at a lower end of the suction ring, and where an inner surface, and optionally an outer surface, of the skirt is coated with medication. The medication includes one or more of the following types of medication: anti-inflammatory, antibiotic, numbing, lubricating, and anti-redness. The coating method may include dip coating, sputter deposition, ultrasonic-spraying, and spin-coating. The skirt may be formed by a process that increases its material porosity and/or surface roughness, and may be surface-treated to enhance adhesion and retention of the medication.

Particular embodiments disclosed herein provide a membrane delamination device for delaminating a membrane from a retina of an eye. The membrane delamination device comprises a blade, a first lever coupled to the blade, and a second lever coupled to the blade. The first lever and the second lever are at least partially housed by a first shaft of a hand-piece. The first lever is fixedly coupled to the first shaft. The second lever is fixedly coupled to the hand-piece. The blade at least partially extends beyond a distal end of the first shaft. The membrane delamination device is configured to be actuated as a result of longitudinal movement of the second lever within and in relation to the first shaft. The second lever moves longitudinally within and in relation to the first shaft due to an application of force to the second lever through the hand-piece.

A system for extracting lens material from an eye including an instrument having a first aspiration pump driven by a drive mechanism having a motor, and an elongate member sized and configured to extend through an anterior chamber to a capsular bag of the eye. The elongate member configured to be oscillated by the drive mechanism includes an inner lumen fluidly coupled to the first aspiration pump and defining at least a portion of an aspiration waste line, and an open distal end having a distal cutting tip. The system can further include a fluid system remote from the surgical instrument including a second aspiration pump and a fluid line configured to deliver background aspiration from the second aspiration pump to the inner lumen of the elongate member to aspirate the lens material from the eye towards the inner lumen. Related devices, systems, and methods are also provided.