Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or optical tissues is performed to address various types of vision correction.

A laser eye surgery system focuses light along a beam path to a focal point having a location within a lens of the eye. The refractive index of the lens is determined in response to the location. The lens comprises a surface adjacent a second material having a second refractive index. The beam path extends a distance from the surface to the focal point. The index is determined in response to the distances from the surface to the targeted focal point and from the surface to the actual focal point, which corresponds to a location of a peak intensity of an optical interference signal of the focused light within the lens. The determined refractive index is mapped to a region in the lens, and may be used to generate a gradient index profile of the lens to more accurately place laser beam pulses for incisions.

An integrated surgical system for accessing one of a plurality of target volumes of ocular tissue in an eye includes a first optical transmission subsystem optically coupled to receive a first light beam, an optics assembly, and a control system. The optics assembly has an optical axis and is configured to couple to the eye to align its optical axis with the optical axis of the eye. The optics assembly is optically coupled with the first optical transmission subsystem to receive the first light beam along one of a plurality of first input axes and to direct the first light beam to a corresponding one of a plurality of first output axes aligned with a corresponding one of the plurality of target volumes of ocular tissue in the eye. The control system is configured to control the first optical transmission subsystem to direct the first light beam into alignment with a select one of the plurality of first input axes.

A method of treating an eye includes delivering an OCT beam along an OCT optical path that enters a first optical subsystem along an input axis, and exits the first optical subsystem along an output axis that: 1) is substantially parallel to the optical axis of the eye, 2) is radially offset from the optical axis, and 3) extends through the cornea and into a portion of the irido-corneal angle at a point along a circumferential angle of the eye. The method also includes imaging the portion of the irido-corneal angle with the OCT beam; delivering a laser beam along an angled optical path that extends through the first optical subsystem, through the cornea, through the anterior chamber, and into a target volume of ocular tissue in the portion of the irido-corneal angle; and photodisrupting at least a portion of the target volume of ocular tissue with the laser beam.

A laser system for treating target tissue layers of an anterior chamber angle of an eye, including a delivery system and various imaging systems is being disclosed here. The system includes novel configurations using small digital cameras, OCT and other diagnostic devices that are integrated with a goniolens to visualize and target the to be treated tissue layers and that in some configurations remain connected and active during the laser treatment. Furthermore, several novel illumination systems and standalone digital camera goniolens systems are being presented here.

The present invention discloses a device suitable for delivery of a fluid composition to an eye, especially therapeutic compositions, comprising: a hollow needle with a bore having a proximal end and a distal end, said distal end configured to pass into a passage in a sclera of an eye, said bore configured to function as a conduit for a fluid from said proximal end to said distal end, and a solid separator having a distal tip, configured to move inside said bore of said hollow needle allowing said distal tip of said separator to protrude from said distal end of said needle.

A method is described of improving adhesion of an ocular implant to corneal tissue by forming an implant adhesive layer on the ocular implant, the implant adhesive layer having greater adhesive strength than a rest of the implant or by forming a corneal adhesive layer on a posterior surface of a posterior portion of the corneal tissue, the corneal adhesive layer having greater adhesive strength than a rest of the corneal tissue.

Embodiments generally relate to ophthalmic laser procedures and, more particularly, to systems and methods for lenticular laser incisions to form a top lenticular incision, a bottom lenticular incision of a lens in the subject's eye, an added shape between the top and bottom incisions where the added shape has no corrective power and a transition ring bisecting both the top and bottom lenticular incisions.

Methods and systems wherein laser induced refractive index changes by focused femtosecond laser pulses in optical polymeric materials or optical tissues is performed to address various types of vision correction.

The assembly for laser treatment of ocular opacities consists of: a measurement system for obtaining depth information regarding ocular structures; a laser system; an eye-tracker unit; a display unit; and a control-and-operating unit. According to the invention, the control-and-operating unit is designed to determine, from the depth profiles, the depth of ocular structures relative to the depth of the laser focus, and, in particular for the retina and the capsular bag, to determine a blocked zone for the laser treatment. Furthermore, the control-and-operating unit is designed to generate, at least for the blocked zones of the retina and capsular bag and the laser focus, at least one tag in each case, the characteristic of which corresponds to the particular depth in the eye, in order to display these tags on the display unit and to overlay them with the live image. The invention relates to a partially automated therapy apparatus for laser treatment of ocular opacities in which two-dimensional views of the eye are combined with three-dimensional imaging from the measurement system.