Technologies are generally described to enhance a signal-to-noise ratio of reflectometry in laser treatment observation through capture of light scattered to the edge of the pupil and filtering of light scattered back around a center of the pupil. Thus, laser light reflected from the treatment site may be spatially filtered to remove a portion of the reflected laser light within a pre-selected angle from a normal of the eye. The captured laser light may be processed to observe an effect of the directed laser beam at the treatment site. The signal-to-noise ratio of the reflectometry may be increased through the spatial filtering.

Systems and methods for performing laser cataract surgery, for using a biometric system to determine a material property of a structure of the eye, laser pulses in a laser shot pattern having different powers. A therapeutic laser, and laser delivery system having the capability to vary the power of the laser beam.

An ophthalmic laser surgical system uses a confocal detector assembly to continuously detect a confocal signal during laser treatment, and based on the confocal signal, detects in real time a loss of tissue contact with the patient interface (PI) output surface. The detection is partly based on the change of reflectivity at the PI output surface when the optical interface changes from a lens-tissue interface to a lens-air interface. The behavior of the confocal signal upon loss of tissue contact is dependent on the treatment laser scan pattern being performed at the time of tissue contact loss. Thus, different confocal signal analysis algorithms are applied to detect tissue contact loss during different scans, such as the bed cut and side cut for a corneal flap. The real time confocal signal may also be used during eye docking to detect the establishment of tissue contact with the PI output surface.

A system and process for treating retinal diseases includes passing a plurality of radiant beams, i.e., laser light beams, through an optical lens or mask to optically shape the beams. The shaped beams are applied to at least a portion of the retina. Due to the selected parameters of the beamspulse length, power and duty cyclethe beams can be applied to substantially the entire retina, including the fovea, without damaging retinal or foveal tissue, while still attaining the benefits of retinal phototherapy or photostimulation.

The present invention concerns a cutting apparatus including a femtosecond laser (1), a shaping system (2) downstream from the femtosecond laser (1), for forming a phase-modulated laser beam, an optical scanner (4) downstream from the shaping system (2), and optical focusing system (5) downstream from the optical scanner (4), a control unit (6) for controlling the shaping system (2), the optical scanner (4) and the optical focusing system (5), characterized in that the apparatus further comprises an optical coupler (3) between the femtosecond laser (1) and the shaping system (2), the optical coupler (3) including a photonic crystal optical fiber for filtering the phase-modulated laser beam (21) coming from the shaping system (2).

The present invention relates to a device for controlling the movement of an ocular therapy apparatus of the type comprising an articulated support arm (2), of which the free end is intended to be placed opposite an ocular tissue, an acquisition system (4) mounted on the arm (2) for acquisition of a measurement pair comprising an image of the ocular tissue, and a signal representative of a vertical distance along the axis Z between the end of the arm and the ocular tissue, characterized in that the control device (5) comprises means for actuating the acquisition system (4), means for processing each measurement pair acquired, and servo means for moving the free end of the arm (2) between an initial position and a desired final position.

Methods and systems enabling the real-time monitoring of a light-induced procedure in a biological medium, and/or the acquisition of information related to this biological medium are provided. In some implementations, the light beam used for the procedure is modulated at a modulation frequency selected in view of the photoacoustic frequency response associated with the procedure. The photoacoustic feedback signal from the medium during the procedure is then monitored. This monitoring may involve filtering the photoacoustic feedback signal around the selected feedback modulation frequency. Ratiometric comparisons of the contribution of different frequencies to the photoacoustic feedback signal are also considered.

A process for safely providing retinal phototherapy includes generating first and second light beams of a different wavelength. The first and second light beams are applied to a retinal pigment epithelium (RPE) and choroid of an eye. The amount of light reflected from the eye from the first light beam and the second light beam is measured, such as using a reflectometer. A level or concentration of the melanin within the eye is calculated using the measured amount of light reflected from the eye from the first and second light beams. When the content or density of melanin in the RPE exceeds a predetermined amount, one or more treatment parameters of the retinal phototherapy is adjusted.

The invention relates to a method for controlling an eye surgical laser for the separation of a volume body from a cornea by controlling the laser by means of a control device such that it emits pulsed laser pulses in a shot sequence in a predefined pattern into the cornea, wherein interfaces of the volume body to be separated are defined by the predefined pattern and the interfaces are generated by the generation of a plurality of cavitation bubbles generated by photodisruption, wherein the plurality of cavitation bubbles is generated along at least one cavitation bubble path and the control device controls the shot sequence of the laser for generating a preset smoothness value such that a common overlap area of the cavitation bubbles is generated at least between adjacent cavitation bubbles located on the same cavitation bubble path depending on a geometry of the respective cavitation bubble. Further, the invention relates to a treatment device, to a computer program as well as to a computer-readable medium.

The invention relates to a method for controlling an eye surgical laser for the separation of a volume body with a predefined posterior interface and a predefined anterior interface from a cornea, comprising controlling the laser by means of a control device such that it emits pulsed laser pulses in a shot sequence in a predefined pattern into the cornea, wherein the interfaces of the volume body to be separated are defined by the predefined pattern and the interfaces are generated by means of an interaction of the individual laser pulses with the cornea by the generation of a plurality of cavitation bubbles generated by photodisruption, wherein the predefined pattern is generated by means of a mesh-like guidance of the emitted laser pulses and the control device controls the shot sequence of the laser such that a common overlap area of the cavitation bubbles is generated between adjacent cavitation bubbles. Further, the invention relates to a treatment device, to a computer program as well as to a computer-readable medium.