A contact assembly (301,400) for laser surgery may include a contact lens (402) and an optical filter (404). The contact lens (402) may be configured to be positioned in an optical path of therapeutic radiation (310) directed at an eye (100) of a patient. The optical filter (404) may be coupled to an outer surface (402A) of the contact lens (402). The optical filter (404) may be transparent to the therapeutic radiation (310) with a first wavelength and may be opaque to radiation (318) with a second wavelength different than the first wavelength.

a laser-based ophthalmological treatment system(200) may include a device housing(202), a head fixation assembly(206), and an interactive display device(324, 424). The head fixation assembly(206) may be configured to position and to retain a head of a patient relative to the device housing(202). The interactive display device(324,424) may be positioned in an optical path(304,404). The interactive display device(324,424) may be fixed relative to the head fixation assembly(206). The interactive display device(324,424) may be configured to display a simulation scene(504) that may include a target image(502) into a visual field of the patient. The target image(502) may be displayed in the simulation scene(504) such that optical focus on the target image(502) by the patient aligns a portion of a fundus(130) of an eye of the patient in the optical path(304,404).

A lens/sensor subassembly (318) may include a feedback sensor (324), a data transmission line (302), and an electrical element (328). The feedback sensor (324) may be configured to measure a phenomenon in an eye (100) of a patient during a laser-based ophthalmological therapy. The data transmission line (302) may be configured to communicate feedback data measured by the feedback sensor (324) to a laser-based ophthalmological treatment system (200). The electrical element (328) may be degradable in response to exposure to therapeutic radiation (316). The degradation of the electrical element (328) may interrupt communication of the feedback data measured by the feedback sensor (324) to the laser-based ophthalmological treatment system (200).

In some embodiments, an ophthalmic laser system may be provided that does not include a traditional laser console. Instead, the treatment device may be configured to house the treatment light source within the device handle. Additionally, in some embodiments, the handheld treatment device may include a user interface, such as dials and buttons, for adjusting various parameters of the therapeutic light. With certain embodiments, the self-contained handheld treatment device may be operated independent of an AC power source. For example, in some embodiments, the handheld treatment device may be battery powered. Additionally, the handheld treatment device may be disposable or may utilize replaceable distal tips in certain embodiments. Certain embodiments may be particularly designed for transscleral cyclophotocoagulation. Also, treatment guides are provided that may be configured to couple with a treatment device to align the device with a target tissue of the eye.

A laser eye surgery system that has a patient interface between the eye and the laser system relying on suction to hold the interface to the eye. The patient interface may be a liquid-filled interface, with liquid used as a transmission medium for the laser. During a laser procedure various inputs are monitored to detect a leak. The inputs may include a video feed of the eye looking for air bubbles in the liquid medium, the force sensors on the patient interface that detect patient movement, and vacuum sensors directly sensing the level of suction between the patient interface and the eye. The method may include combining three monitoring activities with a Bayesian algorithm that computes the probabilities of an imminent vacuum loss event.

Technologies are generally described for customization of treatment based on dosimetric data collected during the treatment. In some examples, a laser treatment procedure may involve the application of multiple laser pulses to a treatment site. During the laser treatment procedure, an effect resulting from the application of one or more of the laser pulses may result in dosimetric data, such as acoustic and/or optical data. The dosimetric data may then be used to determine the efficacy of the laser treatment procedure and/or to adjust, in real-time, a remainder of the laser treatment procedure.

Systems and methods for performing laser cataract surgery, for using a biometric system to determine a material property of a structure of the eye, laser pulses in a laser shot pattern having different powers. A therapeutic laser, and laser delivery system having the capability to vary the power of the laser beam.

Apparatuses and methods for the treatment of glaucoma are provided. The instrument uses either cauterization, a laser to ablate, sonic or ultrasonic energy to emulsify, or mechanical cutting of a portion of the trabecular meshwork. The instrument may also be provided with irrigation, aspiration, and a footplate. The footplate is used to enter Schlemm's canal, serves as a guide, and also protects Schlemm's canal.

Systems for treatment of glaucoma comprise an excimer laser, a plurality of fiber probes, and a processor. Each fiber probe is attachable to the excimer laser to treat a subject having glaucoma by delivering shots from the laser. The processor is configured to monitor and limit a variable number of shots delivered by each fiber probe, the number of shots delivered by each fiber probe programmable within a range. Methods of treating glaucoma include programming a fiber probe to deliver a number of shots from an excimer laser. The fiber probe is inserted into an eye of a subject having glaucoma and adjusted to a position transverse to Schlemm's canal in the eye. A plurality of shots is applied from the excimer laser source while the probe is in the transverse position, thereby treating glaucoma by creating a plurality of perforations in Schlemm's canal and/or the trabecular meshwork.

A method and device for non-invasive monitoring of the temperature of the retina and the retinal pigment epithelium inside the eye, particularly during heating of the bottom of the eye, wherein alternating probing short-duration pulses of light, one at wavelength close to the absorption maximum of the photoreceptor cell type and the other at wavelength in the near-infrared region, are directed at the retinal tissue at appropriate time intervals. Photoreceptor cell electrical signals, photoresponses, are recorded using electroretinography (ERG) and the changes in retinal temperature are determined from changes in photoresponse kinetics and changes in photoreceptor sensitivity to the stimuli. The method is especially applicable at temperatures up to 45 C. for humans and for other animals.