In certain embodiments, a system for calibrating the focal point of a laser beam comprises a laser, focusing optics, detector optics, a two-photon absorption (TPA) detector, and a computer. The laser generates the laser beam. The focusing optics direct the focal point of the laser beam along a z-axis towards a zero-surface corresponding to a zero-plane, and receives a portion of the laser beam reflected by the zero-surface. The detector optics receive the reflected portion from the focusing optics, and directs the reflected portion towards a TPA detector. The TPA detector senses the peak intensity of the reflected portion, which indicates a proximity of the focal point to the zero-surface, and generates a signal representing the peak intensity of the reflected portion. The computer determines whether the focal point of the laser beam is calibrated in response to the signal representing the peak intensity.

A method for measuring the intraocular pressure (IOP) of an eye docked to an ophthalmic surgical laser system via a patient interface assembly. While the eye is docked to the laser system, and as the vertical force exerted on the eye by the patient interface fluctuates as the patient breaths and moves, the amount of corneal deformation is continuously measured by an optical coherence tomography device of the laser system and the force exerted on the eye is continuously measured by force sensors integrated in the patient interface assembly. Based on the real-time force signal and real-time corneal deformation signal, a controller calculates a linear relationship between force and corneal deformation, and determines the IOP of the docked eye by comparing a slope of the linear relationship against a pre-established slope vs. IOP calibration curve. The IOP of the docked eye can be used when setting laser treatment parameters.

In certain embodiments, a device comprises a laser device and a control computer. The laser device directs a laser beam with laser energy through an outer portion of an eye to a target portion of the eye. The control computer receives an optical density measurement of the outer portion, determines the laser energy according to the optical density measurement, and instructs the laser device to direct the laser beam with the laser energy through the outer portion of the eye to the target portion of the eye.

A system for short pulse laser eye surgery and a short pulse laser system, in which a beam guidance device passes through a corresponding articulated arm, and through an applicator head and a microscope head of the system, which is movable in a three-dimensional volume both independently of one another as well as connected to each other. The system also includes, an easy-to-use patient interface with a one-piece contact element, a computer program product for methods of the incision guidance and sequentially operating referencing methods with patient interfaces containing markings.

An RF (radio frequency) positioning system and related method for automated or assisted eye-docking in ophthalmic surgery. The system includes an RF detector system on a laser head and an RFID tag on a patient interface to be mounted on the patient's eye. The detector system includes four RF antennas located on a horizontal plane for detecting RF signals from the RFID tag, where one pair of antennas are located along the X direction at equal distances from the optical axis of the laser head and another pair are located along the Y direction at equal distances from the optical axis. Based on relative strengths and phase difference of the RF signals detected by each pair of antennas, the RF detector system determines whether the patient interface is centered on the optical axis. The RF detector system controls the laser head to move toward the patient interface until the latter is centered on the optical axis.

A measurement apparatus for measuring a laser focus spot size, which includes a two-dimensional image detector and an imaging system which forms a magnified image of a focus spot located an object plane onto the image detector. The imaging system includes at least an objective lens. A sealed liquid container is secured over a part of the objective lens such as the optical surface of the objective lens is immersed in the liquid (e.g. water) within the container. The liquid container has a window through which the laser beam enters. An image processing method is also disclosed which processes the image obtained by the image detector to obtain the focus spot size while implementing an algorithm that corrects for the effect of ambient vibration.

A treatment apparatus for operatively correcting myopia or hyperopia in an eye includes a laser device controlled by a control device and that separates the corneal tissue by applying a laser beam. The control device controls the laser device to emit the laser beam into the cornea such that a lenticule-shaped volume is isolated in the cornea. The control device, when controlling the laser device, predefines the lenticule-shaped volume such that the volume has a minimum thickness of between 5 and 50 m. For myopia correction, the minimum thickness occurs on the edge of the volume, and for hyperopia correction the minimum thickness occurs in the region of the visual axis.

A magnetic positioning system and related method for automated or assisted eye-docking in ophthalmic surgery. The system includes a magnetic field sensing system on a laser head and a magnet on a patient interface to be mounted on the patient's eye. The magnetic field sensing system includes four magnetic field sensors located on a horizontal plane for detecting the magnetic field of the magnet, where one pair of sensors are located along the X direction at equal distances from the optical axis of the laser head and another pair are located along the Y direction at equal distances from the optical axis. Based on relative magnitudes of the magnetic field detected by each pair of sensors, the magnetic field sensing system determines whether the patient interface is centered on the optical axis. The system controls the laser head to move toward the patient interface until the latter is centered on the optical axis.

A laser eye surgery system includes a computer which scans a focused laser beam in a trajectory over a reticle or target and determines beam quality via laser light reflected from the target. The target may have a grid pattern of lines, with the diameter of the focused laser beam determined based on a time interval for the scanned beam to move onto a line of the grid pattern. Methods for measuring beam quality in a laser eye surgery system provide a direct, quantitative quality measurement of the focused laser beam, and may be performed quickly and automatically. Using scanning mirror position information together with signals resulting from laser light reflected from the target, the laser eye surgery system may also be calibrated.

A magnetic positioning system and related method for automated or assisted eye-docking in ophthalmic surgery. The system includes a magnetic field sensing system on a laser head and a magnet on a patient interface to be mounted on the patient's eye. The magnetic field sensing system includes four magnetic field sensors located on a horizontal plane for detecting the magnetic field of the magnet, where one pair of sensors are located along the X direction at equal distances from the optical axis of the laser head and another pair are located along the Y direction at equal distances from the optical axis. Based on relative magnitudes of the magnetic field detected by each pair of sensors, the magnetic field sensing system determines whether the patient interface is centered on the optical axis. The system controls the laser head to move toward the patient interface until the latter is centered on the optical axis.