The present invention relates to an ophthalmic knife and methods of its use for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. The invention relates to a multi-blade device for cutting the tissues within the eye, for example, a trabecular meshwork (TM).

Microkeratome blade assemblies having channels for stabilizing movement are disclosed. According to an aspect, a microkeratome blade assembly including a blade having a cutting edge. The microkeratome blade assembly includes a blade holder attached to the blade. The blade holder defines one or more surfaces for moving across a support portion of a microkeratome head during operation of the blade. The blade holder defines a channel that extends substantially along the same direction as the cutting edge. The channel is shaped and sized for fitting to a corresponding protrusion formed in the microkeratome head.

The present invention provides for a deformable, insertable device for relieving intraocular pressure comprising a body portion composed of a biocompatible porous material with pores throughout to permit drainage of fluid from the anterior chamber to the scleral tissue without collapse of the anterior chamber. The invention also includes a method for inserting the device into the eye and for using ultrasound intraoperatively to determine the position of surgical tools and devices within the sclera. The invention also includes a device excising sclera in an eye to create a chamber for insertion of the insertable device into the eye.

A surgical tool includes a housing having a driver and a surgical blade configured to be bi-directionally rotated by the driver. The surgical tool also includes a footplate configured to receive the surgical blade. The footplate includes a bottom portion configured to rest on ocular tissue of a patient's eye. The bottom portion includes a slot configured to allow passage of a portion of the surgical blade through the bottom portion of the footplate and into the ocular tissue of the patient's eye. The footplate also includes multiple walls having multiple openings. The openings are configured to receive additional portions of the surgical blade such that the surgical blade is rotatable relative to the footplate. The footplate further includes an additional opening or open side configured to allow viewing of the surgical blade and the slot during use.

The present invention relates to an ophthalmic knife and methods of its use for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. The invention relates to a multi-blade device for cutting the tissues within the eye, for example, a trabecular meshwork (TM).

A dissection system for corneal transplants includes a housing including a contact side to be positioned against a cornea. The housing includes an interior passageway with an opening at the contact side. The dissection system includes a blade assembly disposed in the interior passageway. The blade assembly includes a first blade and a second blade. The first blade includes a first cutting edge and the second blade includes a second cutting edge. The first blade and the second blade are movable relative to the housing such that the first cutting edge and the second cutting edge extend through the opening of the housing and out of the interior passageway. The first cutting edge produces a first cut in the cornea. The second cutting edge produces a second cut in the cornea. The first cut and the second cut define a volume of tissue for removal from the cornea.

The present invention relates to an ophthalmic knife and methods of its use for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. The invention relates to a multi-blade device for cutting the tissues within the eye, for example, a trabecular meshwork (TM).

A device for holding and aligning a trephine blade includes an elongated cylindrical component, a first alignment structure and a second alignment structure. The elongated cylindrical component extends along a first axis and comprises a hollow cylinder having an open proximal end, an open distal end, an inner cylindrical surface and an outer cylindrical surface. The first alignment structure is integral and co-planar with the proximal end and comprises a first circle attached to the inner cylindrical surface with one or more radially extending rods. The second alignment structure is arranged parallel to the first alignment structure within the hollow cylinder above the distal end and comprises a second circle attached to the inner cylindrical surface with one or more radially extending rods. The first and second circles are coaxial with the first axis and the first circle comprises a diameter that is greater than a diameter of the second circle.

Disclosed herein is a method and a tool for making tunnel incisions of modified architecture in the cornea and sclera. The tool comprises means for making two additional backward incisions made near the side edges of the main tunnel incision. Additional incisions, made to a depth of 10 to 300 m, are set at an angle of from 15 to 165 relative to the plane of the main tunnel incision. Performing the additional incisions results in a partial downward incision of the tunnel floor (rear part) in its side.

Embodiments of the claimed invention are directed to the treatment of glaucoma (or conditions of elevated intraocular pressure) using a novel ab interno trabeculotomy procedure that uses a flexible device. At least one advantage of the present method is that it does not require a conjunctival or scleral incision, which in turn improves patient recovery time and healing.