The invention relates to a method for leakage detection on at least one flexible test piece in a film chamber, including inserting the at least one test piece into a film chamber, lowering the pressure in the film chamber outside the at least one test piece, and detecting a leakage in the at least one test piece by observing the spatial change of the film of the film chamber. The outer contour of the at least one test piece is transferred to at least one section of the film by the lowering of the pressure in the film chamber. The contour of the film is recorded with an image recording system, and the recorded images of the contour are compared with reference images of said contour in the event of a tight test piece.

A method for leak detection of a test specimen includes providing an evacuable film test chamber which is operatively coupled to a pressure measuring device, and at least one processor operatively coupled to the pressure measuring device; measuring a pressure within the evacuable film test chamber by the pressure measuring device at predetermined times during a measurement period of time; calculating by the processor, a first or higher order derivative of a pressure change with respect to time at a first predetermined time, and a first or higher order derivative of a pressure change with respect to time at least at a second predetermined time during the measurement period of time, to provide at least a pair of derivative values; and categorizing by the processor a leaky or tight state of the specimen under test by a pattern recognition process based on the pair of derivative values.

A leakage inspection method and leakage inspection device for container to be inspected are provided. When a container to be inspected having a deformable flexible part is to be inspected for leakage, the container to be inspected is filled with an inspection gas containing helium, the container to be inspected, which has been filled with the inspection gas, is disposed in an inspection chamber partitioned from the outside, and an upward flow of a carrier gas is formed from the lower part to the upper part of the container to be inspected. A leakage of the inspection gas filled in the container to be inspected is then detected on the basis of the result of measuring the concentration of helium in the carrier gas collected at a position higher than a position where the carrier gas is fed into the inspection chamber.

A mask seal test method, device, and system of using the same are described herein. One method for testing a mask seal can include blocking a respirator cartridge to create pressure within a mask, wherein the mask includes a pressure sensor, measuring pressure values within the mask using the pressure sensor, and notifying a user in response to an increased pressure decay value among the pressure values received by the mask identification reader.

A testing method that includes the steps of evacuating air from a container to a negative atmospheric pressure, the container being a collapsible, flexible container, and comprising at least two opposing flexible walls, wherein a surface of at least one of the walls internal to the container comprises a plurality of channels or recessed features on said at least one wall and monitoring a mass flow or a state of vacuum so as to determine the integrity of the container. The container can be of any size or conformation, with or without attached fittings.

The invention provides a system for detecting leaks in glovebox gloves, the system having a first seal within a glovebox aperture; a second seal contacting exterior surfaces of a glovebox, wherein the exterior surfaces define a periphery of the aperture; a first fluid supply for circumferentially expanding the first seal against center facing surfaces of the aperture to a first pressure; a second fluid supply for inflating the glove to a second pressure; and a pressure gauge for detecting a pressure decrease of the second pressure. Also provided is an in situ method for detecting leaks in glove box gloves, the method having the steps of applying a radially directed force to inside surfaces of cuffs of the gloves to hermetically seal the gloves from the exterior of the glovebox, thereby establishing a seal; inflating the gloves to a pressure; and monitoring the pressure for any decrease in pressure.

A method is provided for detecting leaks in a disposable medical fluid cassette that includes a base and a flexible membrane attached to the base in such a way that the base and the flexible membrane cooperate to at least partially form a fluid passageway. The method includes applying a first force to the flexible membrane, measuring a first physical property of a system that includes the medical fluid cassette a medical fluid pumping machine, removing the first force from the flexible membrane, applying a second force to the flexible membrane, measuring a second physical property of the system, and determining whether the medical fluid cassette leaks based on a comparison of the first physical property and the second physical property.

A delaminatable container is provided that includes a valve member allowing suppression of interference with the motion of a mobile part during use. The present invention provides a delaminatable container including an outer shell and an inner bag, the inner bag to be shrunk with a decrease in contents, wherein the outer shell includes a fresh air inlet communicating an external space with an intermediate space between the outer shell and the inner bag, the fresh air inlet has a valve member mounted thereto to regulate air communication between the intermediate space and the external space, the valve member includes a tube having a cavity provided to communicate the external space with the intermediate space and a mobile part movably stored in the cavity.

A method for calibrating a test chamber, which encloses an interior volume (20), is designed as a film chamber (12) comprising at least one flexible wall region (14, 16), and is connected in a gas-conducting way to a pressure sensor (30), to a vacuum pump (26), and via a calibration valve (34) to a calibration chamber (36) enclosing a calibration volume (37), comprising the following steps: evacuating the film chamber (12); measuring the pressure difference inside of the film chamber (12); after the evacuation has been completed, connecting the calibration volume (37) in a gas-conducting manner to the interior volume (20) of the film chamber (12) while measuring the pressure change, wherein the pressure in the calibration chamber (36) is greater than the pressure in the film chamber (12) before the connection to the film chamber (12). A corresponding device is likewise disclosed.

The present invention relates to a method for a measurement system configured to test a flexible bio-process bag, the method comprising providing at least one flexible bio-process bag having a volume, wherein the at least one flexible bio-process bag is initially filled with a gas and inflated to a reference pressure (Pu), obtaining a leak model, obtaining baseline information, wherein the baseline information comprises at least a weighed first mass value (m.sub.baseline) and a first time value (t.sub.1), obtaining evaluation information, wherein the evaluation information comprises at least a weighed second mass value (m.sub.evaluation) and a second time value (t.sub.2), testing the flexible bio-process bag based on the leak model, the baseline information and the evaluation information.