A microtome includes: a base element; a mid element movably connected to the base element via a joint; a first cutting apparatus element; a second cutting apparatus element; a first actuator apparatus configured to move the first cutting apparatus element relative to the mid element in a delivery direction in order thereby to set a delivery of the object to the blade; a measuring apparatus configured to measure a position of the mid element or of the first cutting apparatus element in the delivery direction relative to a reference; and a controller configured to control the first actuator apparatus on the basis of the position measured by the measuring apparatus. This can compensate the effect of the mechanical play of the joint on the first cutting apparatus element.

Embodiments of the present disclosure relate to a blade holder system based on radio frequency identification (RFID) technology and a controlling method thereof. The blade holder system comprises a blade dispenser, including a blade and a radio frequency identification (RFID) tag, the RFID tag including ID data relating to the blade dispenser; a blade holder, including a radio frequency identification (RFID) reading/writing unit, configured to establish a wireless communication connection with the RFID tag so as to receive the ID data from the RFID tag; and a controller, configured to receive the ID data from the RFID reading/writing unit, to compare the ID data with preset authorization data, and to enable the blade holder to use the blade in the blade dispenser when the ID data matches with the authorization data.

The present disclosure relates to a cutter holder for a microtome. The cutter holder includes: a base; a pressing plate pivotably mounted to the base and having a first end configured to clamp the cutter; an eccentric shaft rotatably mounted in the base; and a sliding assembly slidably mounted in the base. The sliding assembly is arranged between the pressing plate and the eccentric shaft and is in contact with the eccentric shaft, and the sliding assembly is movable towards the pressing plate when the eccentric shaft rotates, so as to force the first end of the pressing plate to clamp the cutter with the base. The cutter holder according to embodiments of the present disclosure allows easy mounting and replacement of the pressing plate, facilitates clamping of the cutter and regulation of a clamping force, and has high working efficiency and high reliability.

A neurostimulation system is shown and described. The neurostimulation system may include a stimulation device implantable into a patient, a lead operatively coupled with the stimulation device, a first power cell providing power to the stimulation device where the first power cell is charged by an externally applied AC (High HF) magnetic field.

An automatic slicing and collecting device, the device including: a first tank, a vibrating microtome, a first pipeline, and a second pipeline. The first tank is filled with a buffer solution. The vibrating microtome is disposed in the first tank. One end of the first pipeline is connected to the vibrating microtome to collect sections, and the other end of the first pipeline is connected to a pump. The pump includes a reversible motor. The first pipeline is provided with a first valve, and a filter is disposed between the pump and the first pipeline. One end of the second pipeline is disposed between the first valve of the first pipeline and the pump, and the second pipeline is provided with a second valve.

Provided is a method of manufacturing a diamond knife for an ultra-microtome, including determining a shape and size of a knife, performing a multiphase flow analysis on movement of a droplet at a fore-end of the knife with the determined shape and size, processing a fine pattern to ensure hydrophobic property according to a result of the flow analysis, and grinding a blade of the knife after the processing of the fine pattern to minimize an interval between the pattern and the blade and, thus, a knife blade is always maintained in a wet state due to a droplet movement between a hydrophobic fine pattern and a hydrophilic surface to continuously generate ultrathin slices.

In the case of a microtome, a pivotable control lever that is designed like a joystick is provided. The functions of the microtome are actuated and regulated by pivoting the control lever and by actuating buttons, which are arranged on the control lever.

Methods, apparatuses and systems for facilitating automated or semi-automated collection of tissue samples cut by a microtome. In one example, a collection apparatus may be moved back and forth between respective positions at which the collection apparatus is operatively coupled to a microtome so as to collect cut tissue samples, or routine access to the microtome is provided. Relatively easy movement and positioning of the collection apparatus is facilitated, while at the same time ensuring structural stability and appropriate alignment and/or isolation between the collection apparatus and the microtome. A fluid reservoir receives samples cut by the microtome, and the collection apparatus may collect samples via a conveyor-like substrate disposed near/in the reservoir. A linear movement of the substrate may be controlled based on a cutting rate of the microtome, and the fluid level in the reservoir may be automatically maintained to facilitate effective sample collection.

This invention relates to apparatus and methods for automated tissue sectioning, including slicing and transferring a tissue section from a microtome. The invention also relates to automated systems and methods for slicing and transferring a tissue section onto a slide.

A microtomy method, blade holder and microtomy apparatus is described in which the microtomy blade or sample block is agitated ultrasonically. The sample block and/or cutting blade may be ultrasonically agitated and the invention provides a device for use in microtomy comprising a blade holder adapted to be agitated ultrasonically and to receive a sample sectioning blade and an ultrasonic source arranged to in use to cause the blade to vibrate in one or more directions within the plane of the blade.