Various embodiments are directed to a fluid composition sensor device and method of using the same. In various embodiments, the fluid flow composition sensor is configured to receive a volume of fluid, the fluid composition sensor comprising a housing, a removable fluid flow component, an impactor nozzle, a collection media assembly dock element configured to receive a replaceable collection media assembly comprising a collection media configured to receive one or more particles within the volume of fluid, an imaging device configured to capture an image of at least a portion of the one or more particles received by the fluid composition sensor, and a controller configured to determine, based at least in part on the image, at least one particle characteristic of the volume of fluid. The imaging device may be configured to capture the image of one or more particles received by the fluid composition sensor using lensless holography.

A device for collecting aerosol particles in an exhaled air flow. The particles may be aerosol particles such as biomarkers or particles related to drugs or other substances formed or found in the alveoli of the lungs. The device comprises an elongate housing with an inner wall and at least four first type partition walls extending substantially perpendicularly from opposite sides of the inner wall to partly cover the cross-section of the housing. The first type partition walls create a labyrinth shaped flow path to divert air flowing from the inlet towards the outlet of the housing in a direction towards opposite inner walls of the housing so that the particles separate from the air flow and attach on the device. The distance between two opposite first type partition walls is smaller than the transverse width of the housing and increases in the flow direction.

A method and apparatus for evaluating the chemical composition of airborne particles by sequentially collecting and analyzing airborne particles in-situ. The method includes: collecting particles; enlarging the particles through water condensation; accelerating the enlarged particles onto a surface to collect enlarged particles; and analyzing the enlarged particles by: isolating the surface; passing a carrier gas over the surface; heating the surface to thermally desorb collected particles into the carrier gas; transporting this evolved vapor into detectors; and assaying the evolved vapor as a function of a desorption temperature. The apparatus includes: a sample flow inlet; a condensational growth tube; a collection and thermal desorption (CTD) cell; a carrier gas source; a heater coupled to the CTD; one or more gas detectors; and a controller configured to operate valves, the heater, the growth tube, and the CTD cell in at least an in-situ sequential collection mode and analysis mode.

One variation of a method includes, during a calibration period: triggering collection of an initial bioaerosol sample by an air sampler located in an environment; and triggering dispensation of a tracer test load by a dispenser located in the environment; accessing a detected barcode level of a barcode detected in the initial bioaerosol sample; accessing a true barcode level of the barcode contained in the tracer test load; and deriving a calibration factor for the environment based on a difference between the detected barcode level and the true barcode level. The method further includes, during a live period succeeding the calibration period: triggering collection of a first bioaerosol sample by the air sampler; accessing a detected pathogen level of a pathogen detected in the first bioaerosol sample; and interpreting a predicted pathogen level of the pathogen in the environment based on the detected pathogen level and the calibration factor.

An embodiment of an assembly for isolating a substrate is described that comprises a vacuum source; a substrate; a receptacle configured to position the substrate and to operatively couple to the vacuum source; and a vessel configured to operatively coupled to the receptacle, wherein the substrate is configured to move from the receptacle to the vessel in response to a differential pressure applied by the vacuum source.

A device and a method for detecting fluid particle characteristics. The device comprises a fluid composition sensor configured to receive a volume of fluid and a controller. The fluid composition sensor comprises a collection media configured to receive one or more particles of a plurality of particles within the fluid; and an imaging device configured to capture an image of one or more particles of the plurality of particles received by the collection media. The controller is configured to determine a particle impaction depth of each of the one or more particles of the plurality of particles within the collection media; and, based at least in part on the particle impaction depth of each of the one or more particles of the plurality of particles, determine a particulate matter mass concentration within the volume of fluid.

Various embodiments described herein relate to apparatuses and methods for detecting fluid particles and their characteristics. In various embodiments, a device for detecting fluid particles and their characteristics may comprise a fluid composition sensor configured to receive a volume of fluid. The fluid composition sensor has a collection media housing configured to receive a portion of a collection media, a pump for moving a volume of fluid over the collection media housing, an imaging device configured to capture an image of particles on the collection media, and a particle matter mass concentration calculation circuitry configured to calculate a total particle matter mass. The particle matter mass concentration calculation circuitry is connected with the imaging device and the pump. The particle matter mass concentration calculation circuitry is configured to adjust the volume of fluid over the collection media housing.

Methods and systems for managing a petri-dish. Embodiments herein disclose a RFID tag affixed on the petri-dish, wherein the RFID tag has a thin formfactor, so as not to interfere in the use and operation of the petri-dish and a sufficiently large readability range. Embodiments herein disclose methods and systems for RFID based asset tracking of petri-dishes in a laboratory/pharmaceutical/manufacturing environment, wherein the movement of the petri-dishes are tracked automatically with minimal manual intervention.

A system and methods of tracking and identifying airborne particles using sensing devices that may include a fan and a collection plate. The fan forces air through the sensing device and airborne particles onto the collection plate. An imaging device captures images of the particles on the collection plate for analysis and identification. An image processing device determines pre-identified particles in the images. The images of other particles are processed and identified by a neural network processing device. Recommendations based on particle counts are provided to a user device. The user device may automatically control one or more devices in response to the recommendations.

The invention generally provides devices and methods for sampling, detecting and/or characterizing particles, for example, via collection, growth and analysis of viable biological particles such as microorganisms. Devices and methods of the invention include particle samplers and impactors for collecting and/or analyzing biological particles in manufacturing environments requiring low levels of particles, such as cleanroom environments for electronics manufacturing and aseptic environments for manufacturing pharmaceutical and biological products, such as sterile medicinal products. Devices and methods of the invention incorporate an integrated sampler and impact surface, such as the receiving surface of a growth media, in a manner to minimize, or entirely eliminate, risks associated with user handling, such as the occurrence of false positive determinations due to contamination of the impact surface during particle sampling, growth or analysis processes.