A method of making a wound dressing comprising the steps of: providing an apertured substrate layer; coating the substrate layer with a fluid silicone prepolymer composition; thermally partially curing said silicone prepolymer composition to form a partially cured silicone coating on the substrate; laminating the coated substrate layer to a base layer to form a laminate having said partially cured silicone coating in contact with a surface of the base layer; followed by exposing the laminate to ionizing radiation, to further cure the partially cured silicone coating and to bond the silicone coating to said surface of the base layer. The radiation cure results in strong bonding between the siliconized substrate and incompatible base layers such as polyurethane foams. Also provided are wound dressings obtainable by the process of the invention.

A method of making a wound dressing comprising the steps of: providing an apertured substrate layer; coating the substrate layer with a fluid silicone prepolymer composition; thermally partially curing said silicone prepolymer composition to form a partially cured silicone coating on the substrate; laminating the coated substrate layer to a base layer to form a laminate having said partially cured silicone coating in contact with a surface of the base layer; followed by exposing the laminate to ionizing radiation, to further cure the partially cured silicone coating and to bond the silicone coating to said surface of the base layer. The radiation cure results in strong bonding between the siliconized substrate and incompatible base layers such as polyurethane foams. Also provided are wound dressings obtainable by the process of the invention.

A system or device for skin closure comprises an elastic flat flexible tape elongated along a longitudinal axis and having a lower side and an opposing upper side, said tape having a pressure sensitive adhesive on at least a portion of the lower side, said tape having a plurality of openings arranged side-by-side with spaces between said openings oriented across the longitudinal axis.

A system or device for skin closure comprises an elastic flat flexible tape elongated along a longitudinal axis and having a lower side and an opposing upper side, said tape having a pressure sensitive adhesive on at least a portion of the lower side, said tape having a plurality of openings arranged side-by-side with spaces between said openings oriented across the longitudinal axis.

A system or device for skin closure comprises an elastic flat flexible tape elongated along a longitudinal axis and having a lower side and an opposing upper side, said tape having a pressure sensitive adhesive on at least a portion of the lower side, said tape having a plurality of openings arranged side-by-side with spaces between said openings oriented across the longitudinal axis.

Disclosed herein is a polyurethane foam sponge produced by the steps of a) providing an hydrophobic polyol which has six hydroxyl groups, b) providing a hydrophilic diisocyanate obtained by reacting a diisocyanate with a hydrophilic polyether diol, c) reacting the hydrophobic polyol with the hydrophilic diisocyanate to obtain a prepolymer which includes 3 to 6 isocyanate groups, and d) mixing the prepolymer with a hydrophilic polyether polyol, a blowing agent, an end-capping agent, a reinforcing agent, and a catalyst to obtain the polyurethane foam sponge. A wound dressing including the polyurethane foam sponge is also disclosed.

A skin patch for the UV protection is contemplated as being formed from a vulcanized silicone substrate, an adhesive gel coating adhered to the internal surface of the silicone substrate, and a release liner removably attached to the adhesive gel coating, wherein following removal of the release liner from the adhesive gel coating, the coating is operative to enable adherence of the skin patch to skin. The skin patch is further contemplated as being operative to at least partially absorb solar ultraviolet radiation via the vulcanized silicone substate or the adhesive coating additionally comprising at least one UV-blocking compound having an absorption peak in the ultraviolet spectrum.

A dressing for treating a tissue site with negative pressure may comprise a tissue interface comprising a three-dimensional textile of polyester fibers and a polymer coating on the polyester fibers. In some examples, the three-dimensional textile may be a three-dimensional weave of polyester fibers, and the polymer coating may be hydrophobic. In more particular embodiments, the polymer coating may be silicone or polyethylene, for example. The dressing may additionally include a drape disposed over the tissue interface and a port fluidly coupled to the tissue interface through the drape. The tissue interface may be applied over a tissue site, and therapeutic levels of negative pressure may be applied to the tissue site through the tissue interface.

To provide an adhesive skin patch being allowed that a carrier layer being in close contact with a backing film layer is easily released after applying to an application site, so as to improve a handleability of the adhesive skin patch.

An adhesive skin patch product includes an adhesive skin patch; a support liner that covers an upper side of the adhesive skin patch, wherein the adhesive skin patch includes an adhesive tape in a form of an approximately strip that includes a backing film and an adhesive layer disposed on a surface of one side of the backing film, a release liner that is attached to the adhesive layer and is longer than the backing film, and a carrier film that is brought into close contact with a surface of the backing film that is opposite to a side of the adhesive layer, wherein the support liner includes a tape backing layer and a support adhesive layer disposed on a surface of the tape backing layer, and the support liner is attached to the carrier film, preferably being attached both to the carrier film and to the release liner, and wherein the carrier film includes one end portion preventing close contact with a surface of the backing film of the adhesive tape, the one end portion being released from the backing film to form a non-attached end portion.

A skin patch for the UV protection is contemplated as being formed from a vulcanized silicone substrate, an adhesive gel coating adhered to the internal surface of the silicone substrate, and a release liner removably attached to the adhesive gel coating, wherein following removal of the release liner from the adhesive gel coating, the coating is operative to enable adherence of the skin patch to skin. The skin patch is further contemplated as being operative to at least partially absorb solar ultraviolet radiation via the vulcanized silicone substrate or the adhesive coating additionally comprising at least one UV-blocking compound having an absorption peak in the ultraviolet spectrum.