A system and apparatus for separating biological tissue and/or biological fluids and in particular a system and apparatus for separating whole blood in order to obtain plasma or platelet-rich plasma which includes embodiments of separation vessels that are rotated about a vertical axis. Some separation vessels include both a separation chamber and a collection chamber. The invention also includes a system and apparatus for mixing biological tissue and/or biological fluids with other materials to create pharmaceutical grade injectables.

Devices and methods for automated liquid handling and reagent processing to provide labelling and detection of bacteria and viruses are provided. Labelling reactions are performed rapidly and with essentially no generation of hazardous waste or use of consumables. Highly sensitive detection is performed by measuring fluorescence on a rotating sample plate.

Methods and devices for continuous flow monitoring of a liquid sample for presence of an airborne microbial pathogen are provided. The liquid sample can be derived from environmental air. The methods and devices provide for continuous labeling of a targeted pathogen in the liquid sample with a fluorescent probe. A customized fluorescence detector is provided that can detect labeled pathogens during continuous flow.

Disclosed is a fluid disposing system including a centrifugal separator that centrifugally separates a liquid that is supplied, a reagent supply module provided on one side of the centrifugal separator and that supplies a reagent to the centrifugal separator, a pipetting module provided at an upper portion of the centrifugal separator and that feeds a fluid to the centrifugal separator, a feeding module coupled to one side of the pipetting module, and that moves the pipetting module in an X axis direction and a Y axis direction corresponding to a horizontal direction, and a Z axis direction that is perpendicular to the horizontal direction, and a separation module including a magnetic bead for magnetically separating a material that has been primarily separated by the centrifugal separator.

A method for establishing mathematical model of relationship between spontaneous imbibition volume and time of porous medium includes sample pretreatment, fully-saturation and centrifugal experiments and NMR T.sub.2 measurement. First, two rock core samples of predetermined size are selected for cleaning and drying. The first rock sample is vacuumed and injected with water to obtain a saturated sample for NMR T.sub.2 measurement. Then, spontaneous imbibition experiment is conducted on another sample, and T.sub.2 measurements are conducted to obtain the water distribution and migration characteristics during the imbibition process. Next, the calculation of the imbibition permeability, average capillary pressure and surface relaxivity are conducted based on the NMR data obtained from two samples. Finally, substitute these parameters into the Handy relationship to obtain a new NMR-based mathematical spontaneous imbibition model.

A separation container for extracting a portion of a sample for use or testing and method for preparing samples for downstream use or testing are provided. The separation container may include a body defining an internal chamber. The body may define an opening, and the body may be configured to receive the sample within the internal chamber. The separation container may further include a seal disposed across the opening, such that the seal may be configured to seal the opening of the body, and a plunger movably disposed at least partially inside the internal chamber. The plunger may be configured to be actuated to open the seal and express the portion of the sample.

A separation container for extracting a portion of a sample for use or testing and method for preparing samples for downstream use or testing are provided. The separation container may include a body defining an internal chamber. The body may define an opening, and the body may be configured to receive the sample within the internal chamber. The separation container may further include a seal disposed across the opening, such that the seal may be configured to seal the opening of the body, and a plunger movably disposed at least partially inside the internal chamber. The plunger may be configured to be actuated to open the seal and express the portion of the sample.

Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate concentrations and the blood pH in an animal, including a human.

Devices, systems and methods for holding and transferring small volume fluid samples are disclosed. Holding vessels, including holding vessels having two or more internal compartments for holding small volume fluid samples, are disclosed. Transfer vessels for receiving small volume fluid samples from such holding vessels are disclosed. Transfer vessels for combining small volume fluid samples from such holding vessels are disclosed. Methods for providing small volume fluid samples for analysis with small loss of sample are disclosed. Methods for providing small volume fluid samples for analysis using automated sample analysis devices and systems, with small loss of sample, are disclosed.

Multi-component separation devices configured to separate components of a liquid sample by centrifugation are provided. Aspects of the separation devices include a container having a distal end and a proximal end and a buoy configured to be displaced along a longitudinal axis within the container where the buoy includes one or more sealed chambers. Also provided are methods of using the subject devices to separate components of a multi-component liquid sample such as whole blood, bone marrow aspirate or stromal vascular fraction as well as systems suitable for practicing the subject methods.