An automatic analysis apparatus includes a reaction vessel configured to contain a reaction liquid in which a measuring object and a reagent are mixed with each other, an irradiation unit configured to irradiate the reaction vessel with irradiation light as predetermined incident light polarization, a measurement unit configured to measure light emitted from the reaction vessel, and a processor configured to process a signal having a specific polarization component obtained from the measurement unit and to analyze the measuring object. The specific polarization component is determined based on the condition of the reaction liquid.

Disclosed herein is a method of characterizing particles in a sample. The method comprises illuminating the sample in a sample cell with a light beam, so as to produce scattered light by the interaction of the light beam with the sample; obtaining a time series of measurements of the scattered light from a single detector; determining, from the time series of measurements from the single detector, which measurements were taken at times when a large particle was contributing to the scattered light; determining a particle size distribution, including correcting for light scattered by the large particle.

A qualification process for a sample to be examined by means of cryo-electron microscopy. The, sample (12) is applied to a sample carrier (10) provided for cryo-electron microscopy and subsequently the sample (12) arranged on the sample carrier is examined by means of dynamic light scattering. The particle size distribution within the sample (12) is determined by means of the dynamic light scattering. Further, a sample holder designed to carry out the qualification process.

Hand-held optical thromboelastographic sensor and method of using the same for simultaneous assessment of multiple parameters of blood coagulation at a point-of-care. The sensor includes an optical system registering laser speckle intensities associated with portions of a blood sample delivered through a fluid switch to analysis chambers of a cartridge of the sensor, and data-processing circuitry programmed to derive the multiple parameters from speckle intensity. The circuitry may be part of a mobile device configured to operate without communication with a central server and/or data storage.

By irradiating target liquid L containing fine bubbles with ultrasonic waves from an ultrasonic irradiation device 102, the fine bubbles in the target liquid L is reduced. By irradiating the target liquid L with ultrasonic waves, fine bubbles in the target liquid L can be reduced effectively. By using ultrasonic waves, bubbles with small diameters, particularly fine bubbles, can be effectively reduced, so that fine bubbles in the target liquid L can be efficiently reduced.

A system includes a method and apparatus suitable for measuring planar drop sizes in a liquid spray. Measurement may involve illuminating the spray with multiple lasers and measuring the scattered intensities at several view angles using linear arrays. The system may use inverse calculation of the measured scattered intensity to estimate the local drop sizes across the entire plane in a spray. The system includes radiation detectors containing sensing elements, a lens systems, and analog to digital conversion board to convert scattered intensities to drop sizes. In addition, the system may include choppers including at least two unique filters. The filters may be selectively placed in a path between the spray and the sensing elements. By selectively placing a single array may measure both a scattered intensity and an extinction of laser light emitted from the spray.

According to one embodiment, a particle measuring method is disclosed. The method includes irradiating a detection liquid with light. The detection liquid contains methyl salicylate. The method further includes converting scattered light from the detection liquid into an electric signal by using photoelectric conversion after irradiating the detection liquid with the light. The method further includes performing a particle measurement on the detection liquid by using the electric signal.

In determining the size of particles in a flowing sample, initially scattered light is detected on a detector, in the form of images, standardization of the measured images takes place and determination of an offset and of an angle of rotation at least of a partial region of two temporally successive images relative to each other is effected. Two images congruent are subdivided into many partial areas with respectively a specific number of pixels and averaging of the brightness values of each individual partial area is implemented. Subsequently, the average brightness value of a partial area of the first image is correlated with the average brightness value of the partial area made congruent with this partial area in the second image (cross-correlation between the images). For each pair of congruent partial areas of the images, a correlation value is thereby produced.

A method and apparatus are disclosed for the collection of light scattered from a liquid sample contained within a multiwell plate for which evaporation from the wells is mitigated by the application of a barrier between the liquid sample and the environment. A vertical thermal gradient is applied across the vessel so that condensation is inhibited from forming on the interior surface of the barrier, thus permitting clear illumination of the sample for visual imaging, fluorescence studies and light scattering detection.

Embodiments of the invention relate to a method and apparatus for measuring at least one parameter that is (i) descriptive of stochastic motion of suspended particles within a fluid; and/or (ii) is a rheological property of the fluid or of the suspension; (iii) describes a concentration of suspended particles within the fluid; and/or (iv) is a diffusion coefficient of the suspended particles and/or (iv) is a viscosity of the fluid or of the suspension; and/or (v) is a food aging or spoilage parameter and/or (vii) is an in-vivo or in-vitro blood coagulation parameter.