Methods and systems for concentrating and allowing for separation of nanoparticles from fluids use acoustically driven nanoparticle concentrators which have an aerogel as the reflecting material and include tuning capabilities to alter the location at which the particles are being concentrated.

At least one embodiment relates to a focusing arrangement for focusing particles or cells in a flow. The arrangement includes at least one channel for guiding the flow. The channel includes (i) at least one particle confinement structure having particle flow boundaries and (ii) at least one acoustic confinement structure having acoustic field boundaries adapted for confining acoustic fields. The acoustic field boundaries may be different from the particle flow boundaries, and the at least one acoustic confinement structure may be arranged with regard to the channel to at least partially confine acoustic fields in the channel.

A particle control method configured prevent an extremely small quantity of particles descending on a stream of a laminar flow in a clean zone through which the laminar flow flows (as in a RABS or isolator device) from descending to a specific position or to guide the particles so as to have them descend to a specific position by controlling movement of the particles. [Solution] A particle descent position is separated away from a board surface of the oscillation board by using an acoustic radiation pressure generated by prompting ultrasonic vibration of the oscillation board disposed with a board surface substantially in parallel with a flow direction of the laminar flow. Moreover, by using a node of a standing wave field generated by prompting the ultrasonic vibration of two oscillation boards disposed with the board surfaces faced with each other, the particle is guided to a direction of a node of a standing wave field. Moreover, by using a focal point of the ultrasonic wave generated by prompting the ultrasonic wave of four oscillation boards, that is, two pairs disposed with the board surfaces faced with each other, the particle is guided to the focal point of the ultrasonic wave.

There are provided an apparatus capable of treating biological particles in a sterile state, and a treatment apparatus. An apparatus for forming a liquid flow including biological particles includes: a chamber member; a sample liquid supply portion; a sheath liquid supply portion; and a vibrating electrode member. The chamber member includes a chamber and a flow cell extending from an interior to an exterior of the chamber. The sample liquid supply portion is configured to supply a sample liquid including the biological particles into the chamber. The sheath liquid supply portion is configured to supply a sheath liquid into the chamber. The vibrating electrode member extends from the interior to the exterior of the chamber, is made of an electrically conductive material, and is configured to be capable of supplying an electric charge to the sheath liquid and the sample liquid in the chamber and propagating an ultrasonic vibration.

Electroacoustic device having a transducer including a piezoelectric substrate, first and second electrodes of inverse polarity having respective first and second tracks provided on said substrate, the first and second tracks spiraling around a same center (C), the transducer being configured for generating a swirling ultrasonic surface wave in the substrate.

The present invention comprises methods and systems that use acoustic radiation pressure.

The present disclosure provides apparatuses, systems, and methods for performing particle analysis through flow cytometry at comparatively high event rates and for gathering high resolution images of particles.

An apparatus for measuring hemolysis in a cartridge based automated blood analyzer is described. The apparatus allows hemolysis testing to be performed on a sample which is presented as a whole blood sample for other testing by the cartridge based automated blood analyzer. A disposable module is configured for optically analyzing one or more plasma analytes in a flow cell while red blood cells are acoustically separated from plasma in the flow cell.

To provide a technique capable of forming stable droplets.

There is provided a microparticle sorting device including a microchip including a main flow path through which a liquid containing a microparticle flows, a sheath liquid flow path that communicates with the main flow path and through which a sheath liquid flows, and a sheath liquid introduction portion that introduces the sheath liquid, in which the sheath liquid flowing through the sheath liquid introduction portion is vibrated. Furthermore, there is also provided a microparticle sorting method including, in a microchip including at least a main flow path through which a liquid containing a microparticle flows, a sheath liquid flow path that communicates with the main flow path and through which a sheath liquid flows, and a sheath liquid introduction portion that introduces the sheath liquid, vibrating the sheath liquid flowing through the sheath liquid introduction portion.

An automatic analyzer for analyzing a medical probe includes an analysis cell for the probe, a piezo element, and an analysis device. The piezo element can be operated by applying a voltage and a frequency, and in the process an acoustic wave field is generated. A probe located in the analysis cell is located in the acoustic wave field when the piezo element is being operated.