Patent classifications
G01N15/1427
Display device
A display device includes a detecting drive unit, an air cleanliness detecting unit and an air cleanliness indicating unit. The air cleanliness detecting unit is configured to detect air cleanliness under the driven of the detecting drive unit and to transmit a detecting result to the air cleanliness indicating unit. The air cleanliness indicating unit is configured to indicate the air cleanliness based on the detecting result of the air cleanliness detecting unit. The display device of the disclosure can conveniently detect the air cleanliness so that a user can live more healthily.
Use of vibrational spectroscopy for microfluidic liquid measurement
This disclosure concerns a cytometry system including a handling system that enables presentation of single cells to at least one laser source. The laser source is configured to deliver light to a cell within the cells in order to induce bond vibrations in the cellular DNA. The system further includes a detection facility that detects the signature of the bond vibrations, wherein the bond vibration signature is used to determine the folding or packing of the DNA.
Apparatus and methods for particle analysis and autofluorescence discrimination
Described herein are apparatuses and methods for analyzing an optical signal decay. In some embodiments, an apparatus includes: a source of a beam of pulsed optical energy; a sample holder configured to expose a sample to the beam; a detector comprising a number of spectral detection channels configured to convert the optical signals into respective electrical signals; and a signal processing module configured to perform a method. In some embodiments, the method includes: receiving the electrical signals from the detector; mathematically combining individual decay curves in the electrical signals into a supercurve, the supercurve comprising a number of components, each component having a time constant and a relative contribution to the supercurve; and quantifying a relative contribution of each component to the supercurve.
MULTI-SPECTRAL MICROPARTICLE-FLUORESCENCE PHOTON CYTOMETRY
A measurement system is disclosed which includes a spot-traversal system for causing relative motion between a sample and an irradiation spot in a first direction, wherein the sample includes one or more fluorescent markers having respective fluorescence wavelengths, a gating system configured to provide a gating signal based at least in part on resultant light substantially at a wavelength of the irradiation spot, and an optical detection system configured to detect fluorescent light from at least some of the fluorescent markers irradiated by the irradiation spot, and provide detection signal(s) representing the fluorescent light detected concurrently with a gate-open condition of the gating signal.
METHOD AND SYSTEM FOR MICROFLUIDIC PARTICLE ORIENTATION AND/OR SORTING
A system for orienting particles in a microfluidic system includes one or more radiation pressure sources arranged to expose particles to radiation pressure to cause the particles to adopt a particular orientation in the fluid. A system for sorting particles in a microfluidic system includes a detection stage arranged to detect at least one difference or discriminate between particles in the fluid flow past the detection stage, and one or more radiation pressure sources past which the particles move sequentially and a controller arranged to switch radiation energy to cause a change in direction of movement of selected particles in the fluid flow to sort the particles. The particles may be biological particles such as spermatazoa. The radiation pressure may be optical pressure and may be from one or more waveguides which may extend across a channel of the microfluidic system.
BIEXPONENTIAL TRANSFORMATION FOR PARTICLE SORTERS
Aspects of the present disclosure include methods for generating a bitmap from a data plot of light detected from particles in a flow stream. Methods according to certain embodiments include detecting light from particles in a flow stream, generating a data plot of measurements of the detected light, where the data plot includes one or more regions each having a population of particles, calculating a set of vertices that form a boundary for each region in the data plot, identifying a type of algorithmic transformation associated with each vertex in the set of vertices, generating a bitmap of each region of particles such that the bitmap of each region includes a set of vertices that correspond to the vertices of each region in the data plot and identifying an algorithmic transformation for applying to each vertex in the bitmap of each region. Systems and integrated circuit devices (e.g., field programmable gate arrays) having programming for generating a bitmap according to the subject methods are also provided.
PARTICLE SORTING DEVICE, PARTICLE SORTING METHOD, PROGRAM, AND PARTICLE SORTING SYSTEM
Disclosed herein are a particle sorting device capable of simply detecting bubbles, foreign substances, or the like in droplets, a method for analyzing particles, a program, and a particle sorting system. The particle sorting device includes a judgment unit, and the judgment unit judges whether or not captured image information including captured droplet image information about a brightness of an image of particle-containing droplets captured after discharge from an orifice has changed with respect to previously-set reference image information including reference droplet image information about a brightness of an image of droplets captured after discharge from the orifice.
Timing and/or phase adjustment of the separation and/or charging of drops from a fluid stream in a flow cytometer
Disclosed is a system for setting the timing or phase of the separation of droplets from a fluid stream in a flow cytometer, or the timing or phase of a charge pulse generator, based upon the collected charge of charged droplets. In one embodiment, a conductive mesh can be used to collect the charged droplets that are either deflected or not deflected by the deflection plates. In another embodiment, the charge can be collected from metal plates in the waste collection device. In addition, a defanning device is disclosed that allows substantially uniform deflection of charged cells.
MICRO PARTICLE ANALYZER AND MICRO PARTICLE ANALYSIS METHOD
The present technology provides a technology for stabilizing break-off timings. Therefore, according to the present technology, there is provided a microparticle analysis device or the like including at least: a flow path in which a fluid including a sample flow containing microparticles and a sheath flow flowing to contain the sample flow; a droplet formation unit configured to form a droplet in the fluid by imparting vibration to the fluid using a vibration element; an electric charge application unit configured to apply electric charge to a droplet containing the microparticles; an imaging unit configured to obtain a photo of a phase of a certain time; and a control unit configured to control a timing at which the droplet breaks off on a basis of the photo.
OPTICAL PARTICLE DETECTOR
Presented is a device (100) for detecting particles, comprising: a first light source (101) positioned for illuminating particles (120) passing through a detection region (130) of the particle detector; a first detector (104) positioned and adapted for detecting light signals from particles illuminated by the first light source (101) in the detection region (130); a processor (110) configured for determining a type of the particles passing through the detection region (130) from light signals detected by the first detector (104); characterized in that: the particle detector (100) further comprises: a means (105) for detecting when particles pass through the detection region (130); and a controller (103) coupled to the means (105) and configured to operate the first light source (101) with a first pulsed current when particles pass through the detection region (130) thereby preserving or extending lifetime of the first light source (101), and wherein the first pulsed current is selected beyond a continuous current damage threshold of the first light source (101) thereby increasing light output of the first light source (101).