A glass vial illumination and inspection system may be provided with a light source and a stand. The stand may have an internal cavity configured to receive at least a portion of the light source. A recess may be located in the stand and configured to receive at least a portion of a glass vial. The stand may be configured to aim the light output from the light source toward the glass vial to illuminate the vial. The stand may be configured to position the vial such that an inspector can manually inspect the illuminated vial for defects. Methods of use are also disclosed.

A housing (20) has a passage port (3) that serves as both the outlet for the illumination light (IL) to go out of the housing (20) toward a sample surface (S) and the inlet for the reflection light (RL) reflected on the sample surface (S) to enter the housing (20). A transparent member (19) is disposed at the passage port (3) to prevent dust including paper dust from entering the housing (20). A light quantity calculation unit (71) calculates the light quantity of light received by a light reception lens (33). A notification unit (81) performs a predetermined notification when the light quantity is less than or equal to a predetermined value.

Aspects of the present disclosure include methods for detecting events in a flow cytometer. Also provided are methods of detecting cells in a flow cytometer. Other aspects of the present disclosure include methods for determining a level of contamination in a flow cell. Computer-readable media and systems, e.g., for practicing the methods summarized above, are also provided.

Aspects of the present disclosure include methods for detecting events in a flow cytometer. Also provided are methods of detecting cells in a flow cytometer. Other aspects of the present disclosure include methods for determining a level of contamination in a flow cell. Computer-readable media and systems, e.g., for practicing the methods summarized above, are also provided.

A droplet sensor system is configured to detect the presence of droplets or other foreign bodies on the surface of a window. The sensor system emits light rays that are coupled into the window, where the window serves as a waveguide that guides the confined electromagnetic radiation across the window. Foreign bodies present on the surface of the glass outcouples a subset of the light as it propagates across the window, attenuating the power of outcoupled light measured at a photodetector mounted near an edge of the window. The system initiates a notification or a control action in response to detecting this attenuation of power due to outcoupling of the propagating light by foreign bodies.

Provided are methods of assessing the cleanliness of a flow cell of a flow cytometric system. The provided methods include computing a ratio of post-flow cell and pre-flow cell light beam intensities and using such a ratio to assess the cleanliness of the flow cell. Flow cytometric systems capable of monitoring the cleanliness of a flow cell contained within the system are also provided.

An infrared (IR) imaging system for determining a concentration of a target species in an object is disclosed. The imaging system can include an optical system including a focal plane array (FPA) unit behind an optical window. The optical system can have components defining at least two optical channels thereof, said at least two optical channels being spatially and spectrally different from one another. Each of the at least two optical channels can be positioned to transfer IR radiation incident on the optical system towards the optical FPA. The system can include a processing unit containing a processor that can be configured to acquire multispectral optical data representing said target species from the IR radiation received at the optical FPA. One or more of the optical channels may be used in detecting objects on or near the optical window, to avoid false detections of said target species.

An infrared (IR) imaging system for determining a concentration of a target species in an object is disclosed. The imaging system can include an optical system including a focal plane array (FPA) unit behind an optical window. The optical system can have components defining at least two optical channels thereof, said at least two optical channels being spatially and spectrally different from one another. Each of the at least two optical channels can be positioned to transfer IR radiation incident on the optical system towards the optical FPA. The system can include a processing unit containing a processor that can be configured to acquire multispectral optical data representing said target species from the IR radiation received at the optical FPA. One or more of the optical channels may be used in detecting objects on or near the optical window, to avoid false detections of said target species.

The present disclosure relates to an optical sensor having a light source that emits light on a sensor layer, wherein the sensor layer can be brought into contact with a medium, wherein the first sensor layer emits emission light as a function of the incident light and a concentration of a measured value of the medium; a receiver, which receives the emission light; a first light guide, which conducts light from the light source onto a first region of the sensor layer and conducts emission light from the first region of the sensor layer to the receiver; and a second light guide independent of the first light guide which conducts light from the light source onto a second region of the first sensor layer and conducts emission light from the second region of the sensor layer to the receiver.

A droplet sensor system is configured to detect the presence of droplets or other foreign bodies on the surface of a window. The sensor system emits light rays that are coupled into the window, where the window serves as a waveguide that guides the confined electromagnetic radiation across the window. Foreign bodies present on the surface of the glass outcouples a subset of the light as it propagates across the window, attenuating the power of outcoupled light measured at a photodetector mounted near an edge of the window. The system initiates a notification or a control action in response to detecting this attenuation of power due to outcoupling of the propagating light by foreign bodies.