An imaging device includes a camera, light sources, an optical bandpass filter, and a conversion unit. The camera includes an image sensor including a N-band color filter (where N is a natural number greater than or equal to 3). The M types of light sources (where M is a natural number that satisfies 2MN) have the emission spectral characteristics of having respective peaks in mutually different wavelength ranges within a visible light range and a near-infrared range. The conversion unit generates image signals of M bands each having spectral sensitivity to the corresponding one of the mutually different wavelength ranges by performing a matrix operation on an N-band imaging signal obtained by the image sensor when an article is photographed with the camera. The light application direction and the emission intensity are individually selected for each of the light sources.

Systems and methods are provided for characterizing a ply of fiber having a thermoplastic veil. One method includes acquiring an image of a fiber material comprising strands of fiber and further comprising a veil of filaments of thermoplastic, subdividing the image into slices, determining an amount of melted filaments depicted within each of the slices, and determining an amount of unmelted filaments depicted within each of the slices.

A laminated fluorescent sensor includes a sealable sensor housing and an optical sensing system embedded inside the sensor housing. The optical sensing system includes a light source (7), a short wave pass filter (8), an air chamber (10), a sensing unit, a long wave pass filter set (12) and an optical signal collecting unit from top to bottom all of which are coaxially set. The optical signal collecting unit is connected with a signal processing system (14); the sensor housing has air inlets (2, 201) and an air pumping port (3), the air inlets (2, 201) are communicated with the air chamber (10) through an air intake passage, the air chamber (10) is communicated with the air pumping port (3) through an air pumping passage. The laminated fluorescent sensor is compact and easy to be arrayed for simultaneously detecting two or more detected objects, has a high signal-to-noise ratio, is applicable in quick detection of micro-trace chemicals including but not limited to explosives and narcotics, provides great detection effects, has distinctly distinguishable signal responses to objects not being detected and to objects being detected, and provides stable and accurate detection.

Among other thing, the present invention provides solution to the problem, particularly, the present invention certain surfaces and certain sample holder to improve the sensitivity, speed, and easy-to-use of an optical signal based assays, such as colorimetric assays or fluorescence assays.

The present invention relates to provide, among other things, the methods, devices, and systems that can simply and quickly collecting and analyzing a tiny amount of vapor condensates (e.g. exhaled breath condensate (EBC)).

In the detection of the presence of a biomarker or the like in a sample of a flowable substance, e.g. a powder or a liquid, usually a body fluid, such as blood, urine, or saliva, for example, a disposable sample receiver (3) is used, which has a receiving chamber (301) that is dimensioned to receive a predetermined volume and is surrounded by a depression (303) receiving any excess volume for which there is no room in the receiving chamber (301). The receiving chamber (301) has a bottom outlet (302) closed by a removable strip (33), e.g. a plastic strip or foil. Upon pulling away the strip (33) from the bottom outlet, the sample in the receiving chamber is emptied into a flow path (32) leading to at least one detection compartment (321) permitting direct visual inspection. Preferably, disposable sample receiver (3) is used in a detector assembly (1) including an electronic camera (23), a CPU (26) and a display (22). Hereby, the volume of the sample to be analyzed will always be the same, and by controlling the exact point of time when the sample is passed on into the flow path (32), a high degree of repeatability and accuracy is achieved, and thereby also a fail-safe system.

Methods for determining surgical margins using an imaging device are described that use multiple cameras to image a biological sample on a turntable bathed in white light or fluorescing due to a systemically administered dye. Fluorescence farther away from an excitation light source can be compensated upon determining a 3-D position of portions of the sample. The turntable is turned and tilted in order to take enough images to prepare an animation of the sample. In a graphical user interface, the animation can be stopped, zoomed, and tilted per a user's gesture, touch, tablet-tilting, or other commands. The image manipulation can be with touch gestures entered using a sterilizable or disposable touch pen.

A multi-well plate reader device includes an opto-mechanical attachment configured to attach/detach to a portable electronic device having a camera. The reader includes a plurality of excitation illumination sources and a slot that receives a well plate. Excitation and emission filters are incorporated into the housing. Optical fibers are located in the attachment and transmit fluorescent light emitted from the wells of the well plate through an optional lens and into the camera. The optical fibers have an input end adjacent to the wells and an output end formed in a header, wherein, in one embodiment, multiple optical fibers are positioned within a cross-sectional area projection defined by the wells and wherein the output ends of optical fibers are mounted in the header. The pattern of the optical fibers is mapped to individual wells in a calibration operation and stored in a fiber map.

A method for determining a property of a geological formation based on an optical image of rock samples taken from the formation is presented therein. The image comprises a plurality of pixels and the method comprises defining windows in the image, each window comprising predetermined number of pixels and being of a predetermined shape. The method also includes, for each window, extracting a rockprint value representative of the window. A rockprint comprises indicators for characterizing a texture of the window. The method also includes classifying the windows into categories of a predetermined set. Each category is representative of one type of rock and the classification is based on a comparison of the rockprint value of each window with rockprint values of images of reference rock samples for each category. Based on the classification, the method then includes determining the at least one property of the geological formation, ie the quantification of each type of rock in the sample.

An imaging device is described that uses multiple cameras to image a biological sample on a turntable bathed in white light or fluorescing due to a systemically administered dye. Fluorescence farther away from an excitation light source can be compensated upon determining a 3-D position of portions of the sample. The turntable is turned and tilted in order to take enough images to prepare an animation of the sample. In a graphical user interface, the animation can be stopped, zoomed, and tilted per a user's gesture, touch, tablet-tilting, or other commands. The image manipulation can be with touch gestures entered using a sterilizable or disposable touch pen.