G01N21/274

Methods and systems for detection of targeted substances
11514609 · 2022-11-29 · ·

A detection system method of color balancing an image includes receiving an image of a test area of a pad which includes a color of a reaction between a test substance and at least one reagent on the test area of the pad, an alignment code having detection system identification information, at least one color calibration block indicia for aligning with a camera as the image is being captured, and test identification information for analyzing the test substance during a colorimetric analysis. The method further includes collecting an array of pixels of RGB values for each pixel in the image, evaluating a captured color of the at least one color calibration block in the image, and performing the colorimetric analysis on the reaction between the test substance and the at least one reagent.

Systems and methods for an absorbance detector with optical reference

Systems and methods are provided for a UV-VIS spectrophotometer, such as a UV-VIS detector unit included in a high-performance liquid chromatography system. In one example, a system for the UV-VIS detector unit may include a first light source, a signal detector, a flow path positioned intermediate the first light source and the signal detector, a second light source, and a reference detector. The first light source, the signal detector, and the flow path may be aligned along a first axis, and the second light source and the reference detector may be aligned along a second axis, different than the first axis.

System for non-invasive measurement of an analyte in a vehicle driver

A system for non-invasively measuring an analyte in a vehicle driver and controlling a vehicle based on a measurement of the analyte. At least one solid-state light source is configured to emit different wavelengths of light. A sample device is configured to introduce the light emitted by the at least one solid-state light source into tissue of the vehicle driver. One or more optical detectors are configured to detect a portion of the light that is not absorbed by the tissue of the vehicle driver. A controller is configured to calculate a measurement of the analyte in the tissue of the vehicle driver based on the light detected by the one or more optical detectors, determine whether the measurement of the analyte in the tissue of the vehicle driver exceeds a pre-determined value, and provide a signal to a device configured to control the vehicle.

Terahertz spectroscopy and imaging in dynamic environments

Embodiments are disclosed for terahertz spectroscopy and imaging in dynamic environments. In an embodiment, a transmitter of an electronic device emits a continuous electromagnetic (EM) wave in the terahertz (THz) frequency band into a dynamic environment that includes a transmission medium that changes over time. A receiver of the electronic device, receives an EM wave reflected off an object in the environment and determines a spectral response of the reflected EM wave. The spectral response includes absorption spectra at a frequency in the THz frequency band that is indicative of a known target transmission medium. The absorption spectra of the target transmission medium and a path length of the reflected EM wave signal are used to obtain the concentration level of the target transmission medium from a reference library of known concentration levels.

OPTICAL DETECTION SYSTEM CALIBRATION

According to a first aspect of the present invention there is provided a method of measuring the optical reflectance R of a target using a detection system comprising a light emitter and a light detector spaced apart from one another. The method comprises illuminating the target with the light emitter, detecting light reflected from the target using the light detector, wherein the light detector provides an electrical output signal S.sub.S indicative of the intensity of the detected light, and determining the optical reflectance R of the target according to (Formula 1), where R.sub.R is the spectral reflectance of a reference standard, S.sub.R is the detector electrical output signal with the reference standard in place, S.sub.H is the detector electrical output signal with no target in front of the light emitter and light detector, and M is a calibration factor.

[00001] R = M .Math. R R s s - s H M .Math. .Math. s R - s H .Math. - R R .Math. s R - s s .Math. , ( 1 )

COMPONENT MEASUREMENT APPARATUS, COMPONENT MEASUREMENT APPARATUS SET, AND INFORMATION PROCESSING METHOD
20220371016 · 2022-11-24 · ·

A component measurement apparatus has a chip insertion space configured to receive a component measurement chip provided with a reagent that reacts with a component to be measured in a sample, and includes: a light emitting unit configured to emit radiation light; a light receiving unit configured to receive the radiation light or light acquired by the radiation light transmitting through or being reflected from the component measurement chip; and a control unit configured to measure the component to be measured in the sample using an actual measurement value of an intensity of received light in the light receiving unit. The control unit is configured such that, when the component measurement chip is inserted into the chip insertion space, the control unit adjusts an amount of the radiation light emitted from the light emitting unit to a predetermined amount of light used in the measurement of the component.

Apparatus and method for estimation concentration of blood compound

A method of estimating concentration of a blood compound may include: removing a baseline drift from Near-Infrared (NIR) spectroscopy data to obtain drift-free spectral features; obtaining a set of global features based on the drift-free spectral features; and estimating the concentration of the blood compound by regression using the set of global features.

SYSTEMS AND METHODS FOR AN ABSORBANCE DETECTOR WITH OPTICAL REFERENCE

Systems and methods are provided for a UV-VIS spectrophotometer, such as a UV-VIS detector unit included in a high-performance liquid chromatography system. In one example, a system for the UV-VIS detector unit may include a first light source, a signal detector, a flow path positioned intermediate the first light source and the signal detector, a second light source, and a reference detector. The first light source, the signal detector, and the flow path may be aligned along a first axis, and the second light source and the reference detector may be aligned along a second axis, different than the first axis.

SURFACE PLASMONIC SENSING

A surface plasmonic sensing device (10) comprises a substrate (12) and a first array (20) and a second array (22) of localised surface plasmon resonance island structures (20, 22) on the substrate (12). The surface plasmon resonance island structures (20, 22) of the first (20) and second (22) array respectively have first and second surface functionalisation for selective interaction with respective analytes. The first surface functionalisation is different to the second surface functionalisation. The first (20) and second (22) arrays are interspersed with each other to provide a composite array in a main sensing region (14) of the device (10). Also disclosed is a method for manufacturing a surface plasmonic sensing device (10) and a method of analysing a fluid comprising a mixture of two or more analytes. The surface plasmonic sensing device (10) may further comprise a reference region (16) and an auxiliary sensing region (18).

OPTICAL PROPERTY MEASUREMENT USING A SENSOR BEHIND A DISPLAY SCREEN
20220364983 · 2022-11-17 ·

Optical property measurement using a sensor behind a display screen Examples of this application disclose a method for measuring optical properties of a target. The method comprises illuminating the target with an illumination area with a display screen in contact with the target, and analysing signals reflected from the target and transmitted back through the display screen to a sensor positioned behind the display screen, to determine the optical properties of the target.