G01N21/39

Systems and Methods for Measuring Concentration of an Analyte

Techniques for acquiring and processing data in combination with a photonic sensor system-on-a-chip (SoC) (1) to provide real-time calibrated concentration levels of an analyte (e.g., a constituent molecule within a biological substance) are described. A raw signal (1300) to be analyzed is collected by the sensor chip (1) via diffuse reflectance or transmittance. Determination of the analyte concentration is based on, in part, Beer-Lambert principles and facilitated by applying (2240) scattering correction to the raw signal (1300) prior to decomposition and analysis thereof.

Systems and Methods for Measuring Concentration of an Analyte

Techniques for acquiring and processing data in combination with a photonic sensor system-on-a-chip (SoC) (1) to provide real-time calibrated concentration levels of an analyte (e.g., a constituent molecule within a biological substance) are described. A raw signal (1300) to be analyzed is collected by the sensor chip (1) via diffuse reflectance or transmittance. Determination of the analyte concentration is based on, in part, Beer-Lambert principles and facilitated by applying (2240) scattering correction to the raw signal (1300) prior to decomposition and analysis thereof.

Optical sensor for surface inspection and metrology
11703461 · 2023-07-18 ·

An optical system configured to measure a raised or receded surface feature on a surface of a sample may comprise a broadband light source; a tunable filter configured to filter broadband light emitted from the broadband light source and to generate a first light beam at a selected wavelength; a linewidth control element configured to receive the first light beam and to generate a second light beam having a predefined linewidth and a predetermined coherence length; collimating optics optically coupled to the second light beam and configured to collimate the second light beam; collinearizing optics optically coupled to the collimating optics and configured to align the collimated second light beam onto the raised or receded surface feature of the sample, and a processor system and at least one digital imager configured to measure a height of the raised surface or depth of the receded surface from light reflected at least from those surfaces.

Optical sensor for surface inspection and metrology
11703461 · 2023-07-18 ·

An optical system configured to measure a raised or receded surface feature on a surface of a sample may comprise a broadband light source; a tunable filter configured to filter broadband light emitted from the broadband light source and to generate a first light beam at a selected wavelength; a linewidth control element configured to receive the first light beam and to generate a second light beam having a predefined linewidth and a predetermined coherence length; collimating optics optically coupled to the second light beam and configured to collimate the second light beam; collinearizing optics optically coupled to the collimating optics and configured to align the collimated second light beam onto the raised or receded surface feature of the sample, and a processor system and at least one digital imager configured to measure a height of the raised surface or depth of the receded surface from light reflected at least from those surfaces.

SYSTEM AND METHOD FOR DETERMINING AT LEAST ONE PROPERTY OF A POROUS MEDIUM

The disclosure relates to system and method for determining at least one property of a porous medium and includes performing a first measurement on a sample of the porous medium obtaining an optical path through pores of the porous medium using a first sensor applied utilizing a first optical technology; performing a second measurement on the sample of the porous medium obtaining a total optical path through the porous medium using a second sensor utilizing a second optical technology different from the first optical technology; and calculating an optical porosity of the porous medium based on the optical path through the pores and the total optical path through the porous medium.

SYSTEM AND METHOD FOR DETERMINING AT LEAST ONE PROPERTY OF A POROUS MEDIUM

The disclosure relates to system and method for determining at least one property of a porous medium and includes performing a first measurement on a sample of the porous medium obtaining an optical path through pores of the porous medium using a first sensor applied utilizing a first optical technology; performing a second measurement on the sample of the porous medium obtaining a total optical path through the porous medium using a second sensor utilizing a second optical technology different from the first optical technology; and calculating an optical porosity of the porous medium based on the optical path through the pores and the total optical path through the porous medium.

Spectrometry device and spectrometry method
11555782 · 2023-01-17 · ·

A spectrometry device includes a switch and a converter. The switch acquires a first reception signal and a second reception signal that respectively include information relating to an optical spectrum and switches between outputting the first reception signal and outputting the second reception signal based on control by a controller. The converter converts the first reception signal or the second reception signal output from the switch into a digital signal.

Spectrometry device and spectrometry method
11555782 · 2023-01-17 · ·

A spectrometry device includes a switch and a converter. The switch acquires a first reception signal and a second reception signal that respectively include information relating to an optical spectrum and switches between outputting the first reception signal and outputting the second reception signal based on control by a controller. The converter converts the first reception signal or the second reception signal output from the switch into a digital signal.

DISSOLVED GAS SENSING SYSTEM AND METHOD

An apparatus and method of use are provided; the apparatus having at least a degasser, a hollow core fiber HCF, an optical mechanism, a detector, and circuitry. The degasser enables gasses to permeate out of a liquid into the degasser interior. The propagator establishes a low-pressure area that helps to pull the gas from the degasser interior into the HCF interior, where the optical mechanism delivers electromagnetic radiation EMR that interacts with the gas. The detector determines EMR absorption, producing output signals which are sent to the circuitry. Circuitry controls the optical mechanism and analyzes the output signals to quantify the concentration of gas in the HCF and in the liquid.

Tunable hybrid III-V/IV laser sensor system-on-a chip for real-time monitoring of a blood constituent concentration level

A spectroscopic laser sensor based on hybrid III-V/IV system-on-a-chip technology. The laser sensor is configured to either (i) be used with a fiber-optic probe connected to an intravenous/intra-arterial optical catheter for direct invasive blood analyte concentration level measurement or (ii) be used to measure blood analyte concentration level non-invasively through an optical interface attached, e.g., to the skin or fingernail bed of a human. The sensor includes a III-V gain-chip, e.g., an AlGaInAsSb/GaSb based gain-chip, and a photonic integrated circuit, with laser wavelength filtering, laser wavelength tuning, laser wavelength monitoring, laser signal monitoring and signal output sections realized on a chip by combining IV-based semiconductor substrates and flip-chip AlGa1-nAsSb/GaSb based photodetectors and embedded electronics for signal processing. Embodiments of the invention may be applied for real-time monitoring of critical blood analyte concentration levels such as lactates, urea, glucose, ammonia, albumin, etc.