[Object] To obtain interference light having a stronger light intensity, and to more accurately measure a refractive index of a measured object, with a simplified configuration.

[Solution Means] A light measurement device 100 includes a phase adjustment unit 120 and a detector 140. The phase adjustment unit 120 outputs reference light E(R) based on object light E1 being light to be obtained by transmission or reflection of light E from a light source with respect to a measured object 200, and signal light E(S) whose phase is adjusted to be different from a phase of signal light. The detector 140 derives a transmission or reflection light intensity distribution or a refractive index of the measured object 200, based on interference light E2 between signal light E(S) and reference light E(R) to be output by the phase adjustment unit 120. An optical axis of light E from a light source is linearly disposed. The phase adjustment unit 120 and the detector 140 are disposed on the optical axis of light E from a light source.

Aspects of the disclosure provide a microfluidic chip to facilitate DNA analysis. The microfluidic chip includes a first domain configured for polymerase chain reaction (PCR) amplification of DNA fragments, a dilution domain coupled to the first domain to dilute a PCR mixture received from the first domain, and a second domain that is coupled to the dilution domain so as to receive the amplified DNA fragments. The second domain includes a separation channel that is configured to perform electrophoretic separation of the amplified DNA fragments. In addition, the disclosure provides a DNA analyzer to act on the microfluidic chip to perform an integrated single chip DNA analysis.

Aspects of the disclosure provide a microfluidic chip. The microfluidic chip includes a first domain configured for polymerase chain reaction (PCR) amplification of DNA fragments, and a second domain for electrophoretic separation. The first domain includes at least a first reaction reservoir designated for PCR amplification based on a first sample, and a second reaction reservoir designated for PCR amplification based on a second sample. The second domain includes at least a first separation unit coupled to the first reaction reservoir to received first amplified DNA fragments based on the first sample, and a second separation unit coupled to the second reaction reservoir to received second amplified DNA fragments based on the second sample. The first separation unit is configured to perform electrophoretic separation for the first amplified DNA fragments, and the second separation unit is configured to perform electrophoretic separation for the second amplified DNA fragments.