A device, method, and system for scheduling the analytical testing and throughput of macromolecular solutions based on light scattering measurements of one or more time dependent macromolecular solution characteristics. A device that includes a plurality of monitoring reservoirs, each configured to receive a macromolecular solution sample, coupled to a light scattering detection instrument configured to monitor light scattering from the plurality of macromolecular solution samples. The device further includes a computing device configured to measure a predetermined time dependent solution characteristic based on the monitored light scattering data and further configured to determine a time for performing an operation on one or more of the macromolecular solution samples based on the predetermined time dependent characteristic measurement.

A blood cell analyzer, a method, and a use of an infection marker parameter. The blood cell analyzer includes: a sample aspiration device for aspirating a blood sample of a subject to be tested, a sample preparation device for preparing a test sample, an optical detection device for detecting the test sample to obtain optical information, and a processor. The processor obtains at least one leukocyte parameter of at least one leukocyte particle population in the test sample from the optical information, obtains an infection marker parameter on the basis of the at least one leukocyte parameter, and outputs the infection marker parameter, the infection marker parameter being used for predicting whether the subject is likely to progress to sepsis within a certain time period starting from when the blood sample to be tested is collected. Therefore, risk of sepsis can be quickly and accurately predicted in advance.

The present invention relates to a blood cell analyzer, a method, and a use of an infection marker parameter. The blood cell analyzer comprises a sample suction device used for aspirating a blood sample to be tested of a subject, a sample preparation device used for preparing a test sample containing a part of a blood sample to be tested, a hemolytic agent, and a staining agent for identifying nucleated red blood cells, an optical detection device used for detecting an test sample to obtain optical information, and a processor. The processor obtains from the optical information at least one leukocyte characteristic parameter of at least one target particle population in a test sample, obtains an infection marker parameter for evaluating an infection status of a subject on the basis of the at least one leukocyte characteristic parameter, and outputs the infection marker parameter.

The invention relates to a device (1), in particular to a cleaning robot, for processing a surface (2), wherein the device (1) has an optical measuring device (3) for determining the type of surface (2). In order to create a surface processing device with an optical measuring device for determining the type of surface that makes it possible to reliably determine the type of surface with little technical outlay, it is proposed that the optical measuring device (3) has a light source (4) and at least two light sensors (5, 6), wherein the light source (4) and a first light sensor (5) are arranged in such a way that light emitted by the light source (4) hits a reflection point (7) of the surface (2) at an angle of incidence (), and then is reflected to the first light sensor (5) at a corresponding angle of reflection (), wherein the light source (4), the reflection point (7) and the first light sensor (5) span a plane of incidence (8), and wherein a secondary plane (9) that intersects the reflection point (7) and has a second light sensor (6) spans perpendicular to the surface (2), and exhibits an angle () of between 80 and 100 relative to the plane of incidence (8), wherein a straight line running through the reflection point (7) and the second light sensor (6) has an angle () relative to the surface (2) that is essentially as large as the angle of incidence () or angle of reflection ().

Systems for the monitoring of bacterial levels in samples, using spectral analysis of the light diffracted from a substrate with an ordered array of pores having diameters enabling the targets to enter them. The trapping pore array is cyclically illuminated by light of different wavelengths, and the light diffracted from the pore array is imaged by a 2-dimensional detector array, with one pixel, or a small group of pixels receiving light from each associated pore. The temporal sequence of frames provides a series of images, each from the reflection of a different wavelength. A time sequenced readout of the signal from the pixel or pixels associated with each pore region, provides a spectral plot of the reflected light from that pore region. Spectral analysis of the light intensity from this series of different wavelength enables the effective optical thickness (EOT) of each pore to be extracted.

A method and device for optically detecting particles, including: (a) a cell wall of rectangular cross-section is fitted on a longitudinal surface and adjoining transverse surface with an L-shaped heating and cooling element; (b) the center of the transverse surface of the cell wall opposite the transverse surface which forms the support of the cell wall is irradiated by an irradiation device and is observed at right angles to the optical axis of the irradiation device; (c) the focus of the irradiation device and the observation device can be moved by a motor to any point in the three-dimensional inner region defined by the cell wall; (d) the surface of the cell wall opposite the optical glass window through which the radiation from the irradiation device enters comprises another optical glass window; (e) the temperature of the surface of the cell wall is monitored by two thermistors.

A method for detecting a contamination of a cuvette of a turbidimeter. The turbidimeter includes a light source which emits a light beam directed to a cuvette, a scattering light detector, and a diffuser with a body and an actuator. The actuator moves the body between a parking position and a test position where the body is between the measurement light source and the cuvette, thereby interferes with the light beam, and generates a diffuse test light entering the cuvette. The method includes activating the actuator to move the body from the parking position into the test position, activating the light source, measuring a test light intensity received by the scattering light detector, comparing the test light intensity measured with a reference light intensity, and generating a contamination signal if a difference between a reference light intensity and the test light intensity measured exceeds a first threshold value.

This blood analyzer includes a sample preparation portion preparing a measurement sample free from a labeling substance from a blood sample and a hemolytic agent free from a labeling substance, a light information generation portion generating fluorescent information and at least two types of scattered light information from the measurement sample and a control portion performing a first classification of white blood cells in the measurement sample into at least four groups of monocytes, neutrophils, eosinophils and others on the basis of the fluorescent information and the two types of scattered light information.

A method for determining a turbidity of a medium in a container using at least one turbidity sensor. Depending on the ambient conditions at the installation location of the turbidity sensor, comprising the following steps: passing transmitted radiation through the medium, wherein the transmitted radiation is converted by interaction with the medium, as a function of the turbidity in the received radiation; receiving the received radiation; converting the received radiation into a scattered light intensity, and determining the turbidity from the scattered light intensity. The method is characterized by the following steps: detecting the chronological sequence of the scattered light intensity; determining a mean value on the basis of the chronological sequence of the scattered light intensity; determining the turbidity from the mean value using a calibration model by assigning a turbidity to each mean value; determining a corrected mean value on the basis of the chronological sequence of the scattered light intensity, by determining a noise parameter from the scattered light intensity, and by determining the corrected mean value from the noise parameter using a noise model, and determining a corrected turbidity at least from the corrected mean value using the calibration model by assigning a corrected turbidity to each corrected mean value. The invention further relates to a turbidity sensor for implementing the method.

Simultaneous Multiple Sample Light Scattering systems and methods can be used for polymer stability testing and for applying stressors to polymer or colloid solutions including heat stress, ultrasound, freeze/thaw cycles, shear stress and exposure to different substances and surfaces, among others, that create a polymer stress response used to characterize the polymer solution and stability.