Disclosed herein are systems and methods for measuring one or more target analyte concentrations, particularly peroxyacid compounds, in a process solution, for example, in industrial and commercial water. These systems and methods include automated methods to measure the target analyte concentration in the process solution. The methods have the advantage of providing a large dynamic range for measurement and can be used in a wider range of process solutions.

The molecule detecting apparatus of an embodiment includes a light source 31, a fluorescent layer 42 emitting different fluorescence depending on the kind of a target molecule 60 captured when being irradiated with light from the light source 31, a photodetector 32 configured to detect fluorescence, and the photodetector 32 is an array of avalanche photodiodes operating in Geiger mode.

Various techniques are provided to implement, operate, and manufacture a chemical detection device. In one embodiment, a device includes a flow path comprising an analyte reporter configured to receive samples passed by the flow path. The device also includes an excitation source configured generate a response from the analyte reporter. The device also includes a detector configured to receive the response from the analyte reporter to determine whether the samples comprise a material of interest. The device also includes a support structure configured to position the flow path relative to the excitation source and the detector, wherein the support structure comprises a carbon filled polymer material. Additional devices, systems, and methods are also provided.

A method of analyzing for the presence or concentration of an analyte in a liquid in microgravity is disclosed. The method includes removing a first quantity of the liquid from a first container and passing the removed liquid through a porous pad that includes a reagent that is responsive to the analyte. The presence or concentration of the analyte in the liquid is determined based on a response of the reagent. The removed quantity of liquid is transferred back to the first container or to a second container, and followed by disposal of the first or second container.

Provided is a biosensor. The biosensor includes a substrate, an optical structure provided on the substrate, and a cover provided on the substrate and having a bridge shape that is in contact with a top surface of the substrate at both sides of the optical structure. The cover has a channel extending in a first direction, the optical structure is provided inside the channel, and the optical structure is configured to capture biomaterials that travel through the channel.

An interferometric chip is provided that includes a substrate having one or more waveguide channels having a sensing layer thereon. Related methods are also provided.

A lateral flow assay device includes several markers, a color bar, and/or a grayscale on the housing of the lateral flow assay device. The markers are used to assist in focusing a mobile device's camera on the control line of the lateral flow assay device. The markers may be used to adjust the perspective of an image taken from the control line and the test line of the lateral flow assay device. The markers may be used to locate the images of the control line, the test line, the color bar, and/or the grayscale on the image. The image of the color bar and the grayscale may be used to adjust the colors and intensity of the image. The images of the test line and the control line may then be used to determine the test results of the lateral flow assay device.

An apparatus and examples of methods for using and manufacturing aspects of an apparatus with a sensor having an active surface. A sensor, a lid, and a flow channel bounded by the lid and a surface of the sensor, and including an illumination source, a heater, and a pump. A method includes fluidically coupling a first flow cell and a second flow cell to a reservoir, moving fluid from the reservoir into a flow channel of the first and second flow cell using respective pumps; and heating fluid in the flow channels of the first and second flow cells using respective heaters. A method includes forming a first sensor and a second sensor on a flexible surface, and folding the flexible surface until the first sensor faces the second sensor.

An embodiment includes a sample receiving region, a first diagnostic element that includes one or more colorimetric analysis regions, and a second diagnostic element that includes one or more lateral flow assay analysis regions. The embodiment also includes a first flow path that allows a portion of a liquid deposited at the sample receiving region to flow to the first diagnostic element. The embodiment also includes a second flow path that allows a portion of the liquid deposited at the sample receiving region to flow to the second diagnostic element.

A cartridge comprises a housing; a sample mixing compartment disposed within the housing, the sample mixing compartment comprising: an activation pouch, and a sample collection region; and a gas transporter tube having a first end and a second end, the tube being disposed within the housing adjacent to the sample mixing compartment, wherein the sample mixing compartment is partially defined by a moveable door of the housing, the moveable door providing access to the sample mixing compartment when the door is in an open position and preventing access to the sample mixing compartment when the door is in a closed position; and wherein the door is configured to release contents of the activation pouch upon movement from the open position to the closed position.