G01N2021/7766

Microcapillary sensor array

A microcapillary sensor array includes a sensor body that is elongated along a longitudinal axis. The sensor body has a first end, a second end spaced from the first end along the longitudinal axis, an outer surface, and an inner surface. The inner surface defines a hollow capillary that extends from the first end toward the second end along the longitudinal axis. The microcapillary sensor array includes a sensing element that extends through the sensor body from the outer surface to the hollow capillary and a conductive element in contact with the sensing element. The conductive element detects a response signal generated by a reaction between the sensing element and a fluid as the fluid flows through the hollow capillary contacting the sensing element.

SYSTEM AND METHOD FOR MEASURING ANALYTE CONCENTRATION IN BODILY FLUIDS
20210293719 · 2021-09-23 ·

A system and kit for measuring analyte concentration in a bodily fluid include a durable component, at least one indicator component including an indicator zone, and at least one moisture sensor. The kit has multiple individually packaged indicator components. Methods of measuring analyte concentration in bodily fluids include the steps of collecting and transporting bodily fluid to at least one colorimetric analyte sensing element and detecting the presence of bodily fluid in contact with the at least one colorimetric analyte sensing element, collecting optical data relating to the at least one colorimetric analyte sensing element with at least one spectrophotometer after a predetermined time period after detecting the presence of bodily fluid, communicating the optical data to a computing system having at least one processor and data storage, and analyzing the optical data to determine at least one analyte concentration in the bodily fluid.

PREDICTIVE METHOD USING COLORIMETRIC ANALYSIS OF BODILY FLUIDS
20210293720 · 2021-09-23 ·

A method for predicting risk of a future disease condition includes the steps of collecting and transporting bodily fluid to at least one colorimetric analyte sensing element, detecting the presence of bodily fluid, collecting optical data relating to the at least one colorimetric analyte sensing element with at least one spectrophotometer after a predetermined time period after detecting the presence of bodily fluid in contact with the colorimetric analyte sensing element, communicating the optical data to a computing system having at least one processor and data storage, analyzing the optical data to determine at least one analyte concentration in the bodily fluid, identifying a threshold analyte concentration of the at least one analyte in the bodily fluid that is an indicator of the risk of developing a future disease condition; and recording the at least one analyte concentration in the bodily fluid over time.

DISPOSABLE INDICATOR COMPONENT FOR MEASURING ANALYTE CONCENTRATION IN BODILY FLUIDS
20210293792 · 2021-09-23 ·

A disposable indicator component for use in a system for measuring analyte concentration in a bodily fluid includes an indicator zone comprising at least one colorimetric analyte sensing element, and a coupler for coupling the indicator component to a component having at least one spectrophotometer contained within a housing.

SOIL, MOISTURE INDICATOR, WATER DETECTION UNIT USED IN SOIL, MOISTURE INDICATOR, BODY CASE, MANUFACTURING METHOD FOR WATER DETECTION UNIT, AND MANUFACTURING METHOD FOR SOIL MOISTURE INDICATOR
20210190743 · 2021-06-24 · ·

A soil moisture indicator contains a water-absorbing material and a color-changing part. A body part is formed and hollow by a material through which water does not pass, and has a water-absorbing opening proximate one end and a transpiration opening positioned near the other end. A display part is connected to the other end of the body part and allows an inner hollow portion to be viewed. An upper-end part that constitutes the end portion of the display part can be removed from and connected to the display part at the end portion on the opposite side to the end portion connected to the body. There is a change in color tone indication between a water-absorbed state and a dry state.

CAPILLARY-BASED SYSTEM FOR ACCELERATED ANTIMICROBIAL SUSCEPTIBILITY TESTING
20210189453 · 2021-06-24 ·

Provided are systems, devices, kits, and methods that are used for antimicrobial sensitivity testing (AST). The systems, devices, kits, and methods provide a capillary-based antimicrobial susceptibility testing platform referred to as “cAST” that provides faster determination of antimicrobial susceptibility using lower sample volumes than previous approaches. The cAST approach includes performing AST by measuring colorimetric or fluorescent signal changes in samples in conduits that contain antimicrobial agents and one or more dyes. The conduits are operably linked to a light source and a light detecting component through a mount configured to hold the conduits and thereby determine changes in light that indicates changes in bacteria growth in the present of the antimicrobial agents.

System and method for sample collection, transport and analysis
10677807 · 2020-06-09 ·

A system and method for collecting, transporting, and analyzing dried bodily fluid samples using a sample collection device incorporating extraction markers, an imaging device to take images of dried samples on the collection device, and a computing device to analyze data points from the images so as to measure various properties of the collected sample such as the volume of blood initially collected, and the portion of that volume containing plasma and erythrocytes.

Predictive method using colorimetric analysis of bodily fluids

A method for predicting risk of a future disease condition includes the steps of collecting and transporting bodily fluid to at least one colorimetric analyte sensing element, detecting the presence of bodily fluid, collecting optical data relating to the at least one colorimetric analyte sensing element with at least one spectrophotometer after a predetermined time period after detecting the presence of bodily fluid in contact with the colorimetric analyte sensing element, communicating the optical data to a computing system having at least one processor and data storage, analyzing the optical data to determine at least one analyte concentration in the bodily fluid, identifying a threshold analyte concentration of the at least one analyte in the bodily fluid that is an indicator of the risk of developing a future disease condition; and recording the at least one analyte concentration in the bodily fluid over time.

Coupon design for enhanced color sensitivity for colorimetric-based chemical analysis of liquids

A system for monitoring an analyte concentration in liquid is provided. The system includes a coupon comprising an absorbent body with a window through the absorbent body wherein the liquid is maintained in said window by capillary action and surface tension. A reactant is in the absorbent body wherein the reactant is capable of diffusing into the window to react with an analyte in the liquid, or the reactant is able to react with the analyte within the coupon itself, with color-indicating by-products of the reaction diffusing into the window, wherein the analyte is present in an analyte concentration, to form a reactant with a color wherein the color has an intensity which correlates to the analyte concentration. A light source is provided which is capable of passing light into the window wherein the light is attenuated by the color proportional to the analyte concentration to form attenuated light. A detector is provided which is capable measuring an intensity of the attenuated light. Alternatively, the color change can be read by eye and compared to a color chart relating the color to an analyte concentration.

MICROCAPILLARY SENSOR ARRAY
20190339252 · 2019-11-07 · ·

A microcapillary sensor array includes a sensor body that is elongated along a longitudinal axis. The sensor body has a first end, a second end spaced from the first end along the longitudinal axis, an outer surface, and an inner surface. The inner surface defines a hollow capillary that extends from the first end toward the second end along the longitudinal axis. The microcapillary sensor array includes a sensing element that extends through the sensor body from the outer surface to the hollow capillary and a conductive element in contact with the sensing element. The conductive element detects a response signal generated by a reaction between the sensing element and a fluid as the fluid flows through the hollow capillary contacting the sensing element.