The present invention relates to a sensor using a tilted fiber grating to detect physical manifestations occurring in a medium. Such physical manifestations induce measurable changes in the optical property of the tilted fiber grating. The sensor comprises a sensing surface which is to be exposed to the medium, an optical pathway and a tilted grating in the optical pathway. The grating is responsive to electromagnetic radiation propagating in the optical pathway to generate a response conveying information on the physical manifestation.

An optical sensing platform with an array of sensors, a laser or broadband light source and an optical detector that utilizes surface plasmon resonance based transduction and optical detection is provided. The sensor structure of the platform has a low index support layer, a high contrast grating, a low index spacer and a thin metal film with a target recognition element. The surface plasmon resonance based sensor uses surface plasmon waves to detect changes on the surface of the sensor when a target interacts with the target recognition element. The binding of the target with a recognition element receptor will induce changes in the refractive index of the metal layer, which changes the resonance wavelength of the plasmon wave on the sensor surface, which is used to measure or observe the reaction.

A sensing apparatus includes a light source to transmit a light beam, an input switch, a first sensing element, a second sensing element, and a detector. The input switch receives the light beam and includes a phase change material having a first state and a second state. The first sensing element receives the light beam from the input switch when the phase change material is in the first state and produces a first change in the light beam in response to a presence of a first analyte. The second sensing element receives the light beam from the input switch when the phase change material is in the second state and produces a second change in the light beam in response to a presence of a second analyte. The detector detects the first change and/or the second change in the light beam.

An optical sensor system is provided which can be used not only as an ordinary light source, but also to calculate an environmental parameter. Rear surface outgoing light (31) output from a rear surface (21) of a semiconductor laser (10) is used in a process of calculating an environmental parameter by control and arithmetic device (60) to, while front surface outgoing light (30) output from a front surface (20) is used in an application other than the calculation of the environmental parameter.

A multi-path interferometric sensor for sensing small changes in the refractive index of sensing arms thereof, such as caused by the presence of an analyte or changes in analyte concentration, is disclosed. The sensor includes a single light source, a single detector, and a plurality of interferometers or a single multi-path interferometer. The various sensing branches within the multi-path interferometric sensor each include a delay having a different length. This results in a different modulation frequency for each interferometer, each of carriers include phase information that correlates to a change in refractive index and, ultimately, analyte concentration. The plural carrier frequencies enable simultaneous detection of multiple samples.

The present disclosure is to provide a measurement chip, a measuring device, and a measuring method which can accurately estimate an analyte concentration with a simple configuration. A measurement chip may include a propagation layer, an introductory part, a drawn-out part and a reaction part. Through the propagation layer, light may propagate. The introductory part may introduce the light into the propagation layer. The drawn-out part may draw the light from the propagation layer. The reaction part may have, in a surface of the propagation layer where a reactant that reacts to a substance to be detected is formed, an area where a content of the reactant changes monotonously in a perpendicular direction perpendicular to a propagating direction of the light, over a given length in the propagating direction.

The present invention relates to sensors for detecting the presence or measuring the concentration of a target analyte, the sensor comprising: (i) a first phase comprising a first crosslinked polymer; (ii) a second phase comprising a second crosslinked polymer; and (ill) a target analyte recognition agent; the first phase and second phase arranged to form an optical grating. The first crosslinked polymer comprises low amounts of a crosslinking agent. The present invention also relates to methods of making a sensor for detecting the presence or measuring the concentration of a target analyte.

The present invention relates to a sensor using a tilted fiber grating to detect physical manifestations occurring in a medium. Such physical manifestations induce measurable changes in the optical property of the tilted fiber grating. The sensor comprises a sensing surface which is to be exposed to the medium, an optical pathway and a tilted grating in the optical pathway. The grating is responsive to electromagnetic radiation propagating in the optical pathway to generate a response conveying information on the physical manifestation.

Systems and methods for detection of an amphiphile at a liquid crystal interface include the production of circular polarized light. A system 100 for detecting an amphiphile at a liquid crystal interface comprises a source of white collimated light. A circular polarizer is included for circularly polarizing incoming white light. Polarized white light passes through to an LC grid including a suspended LC film and a solution in contact with the LC grid at a surface. A spectrophotometer optically detects the presence of an amphiphile at the surface by determining a change in birefringence exhibited by the suspended LC film. A method for detecting amphiphiles at a liquid crystal water interface comprises shining collimated white light on an LC cell including an LC film, polarizing the white light with a circular polarizer, adding an amphiphile to a solution in contact with the LC film, and optically detecting the presence of the amphiphile by measuring a change in birefringence exhibited by the LC film.

An optical sensor arrangement for measuring an observable including at least one light source for generating a first light component of a first frequency including a first mode and a second light component of a second frequency including a second mode orthogonal to the first mode, an optical resonator having differing optical lengths for the first and second modes, at least one of the optical lengths being variable depending on the observable and a dependence of the respective optical length being different for the first and second modes, and a detector unit coupled to the optical resonator for coupling out the two light components and being configured for detecting a frequency difference between a resonance frequency of the optical resonator for the first mode and a resonance frequency of the optical resonator for the second mode.