A test reagent includes a reactant and a sheet-shaped member. The reactant is in a dry state and specifically reacts with a test substance. The sheet-shaped member holds the reactant and disperses in a solvent solution in which the reactant dissolves.

Devices and methods for the hook effect detection associated with analytes of interest in the conductance of one or more diagnostic assays, including, without limitation, immunoassays.

Devices and methods for the hook effect detection associated with analytes of interest in the conductance of one or more diagnostic assays, including, without limitation, immunoassays.

An automatic analyzer disclosed herein includes a first calibration curve generator configured to generate a first calibration curve indicating a relationship between a concentration and an absorbance based on a result of an optical measurement of a reaction solution obtained by adding a reagent to a reference sample including a known concentration of an object to be detected; and a corrected calibration curve generator configured to generate, after the first calibration curve is generated, a corrected calibration curve based on a result of an optical measurement of a mixed reaction solution obtained by mixing the reagent and the reference sample or water, or an optical measurement of the reagent, and data relating to the first calibration curve.

Provided are an analysis device, an analysis method, and the like that predict a concentration even for a sample having high concentration that can be outside a measurement range as it is, using an absorbance measurement result in a reaction course at the time of measurement of a test liquid containing an immunological reagent and the sample, and determine an optimum dilution rate to conduct measurement. As the present invention, for example, an analysis device having means (A) that detects a prozone during measurement of a sample, and means (B) that determines a high concentration region by automatically determining a dilution rate of the test liquid can be recited.

This invention provides a stool specimen test device comprising: a suction port of a sample comprising a stool suspension; a sampling verification section that detect a specimen without the collected stool sample based on the absorbance of the stool suspension measured at the first wavelength; and a sample measurement section that performs measurement based on the absorbance measured at the second wavelength. This invention can improve the test accuracy by detecting a specimen without the collected stool sample in the stool specimen test.

An example system includes a chamber to hold a mixture that includes a whole blood sample from a patient, a light source to illuminate the mixture in the chamber, a detector to detect light from the light source transmitted through the mixture in the chamber, and one or more processing devices to determine, based on the light detected by the detector, a platelet aggregation value of the whole blood sample that is substantially independent of a hematocrit of the whole blood sample.

To provide a method of detecting a target substance in which silica particles are used, and a sensitizing factor is increased without any reduction in measurement accuracy, provided is a method of detecting a target substance including: a first step of mixing a specimen liquid containing at least the target substance and a particle dispersion, which comprises first particles each having a site that specifically binds to the target substance, to produce a liquid sample; and a second step of performing the optical measurement of the liquid sample, wherein the liquid sample comprises second particles, wherein the ratio of the average particle diameter of the second particles to the average particle diameter of the first particles in the liquid sample is 0.03 or more and 0.24 or less, and wherein the refractive index of the second particles is smaller than the refractive index of the first particles.