G01N21/9508

Drug anomaly detection

A portable anomaly drug detection device is disclosed. The device includes at least one light source, a detector to scan or process the subject drug, and a control circuit having a controller. The at least one light source, the camera, and the control circuit are disposed within an enclosure. The controller is configured to process and analyze drug images captured by the camera when the light source emits light, and determines whether a drug is counterfeit upon detection of an anomaly within the captured images relative to a trained counterfeit detecting machine-learning model.

TABLET INSPECTION SYSTEM MANUFACTURING MODULE WITH INDIVIDUAL REJECTION METHOD AND VERIFICATION OF REJECTION
20220267036 · 2022-08-25 ·

A tablet inspection and rejection verification module designed to integrate into a manufacturing line for tablets. The module being magnetically separable into a rejection portion, verification portion, and rejection collection portion of the module for easy replacement or cleaning. The module having a design to work in multi-channel tablet filling equipment. The module operates based on a predetermined good-bad inspection that communicates to the module that a tablet(s) needs to be removed from the filling process, and wherein the module upon rejection also has a method of verification of defective tablets moving in the good-tablet channel resulting in bottle rejection.

Sensor assembly for moving items and related filling machine and methods

A sensor system for evaluating an item as it moves includes a sensor assembly including a plurality of emitters and a plurality of detectors disposed about an item movement path. A controller is configured for selectively operating the sensor assembly to set up a first active detection pattern through the item movement path by sequentially and rapidly checking an occlusion status of each of a first plurality of emitter to detector light paths that make up the first active detection pattern, such that only one emitter to detector light path of the first plurality of emitter to detector light paths is checked for occlusion at a given instance.

Tablet counter and packaging module and associated method

A tablet counter and packaging module including a rotary disc with tablet apertures spaced thereabout, the tablet apertures configured to receive a tablet; a negative pressure system configured to retain the tablets in the tablet apertures; ejection devices to selectively eject one or more of the tablets from the corresponding tablet apertures; a plurality of ejection receptacles configured to collect the tablets ejected by the ejection devices; an inspection system operably engaged with the rotary disc and at least one of the ejection devices, the inspection system being configured to analyze tablets retained within the tablet apertures to determine if one or more tablet characteristics associated with the tablet; and the ejection devices configured to eject the tablet from a tablet aperture based on the determined at least one tablet characteristic.

WEARABLE DEVICE COUPLED TO TIME-OF-FLIGHT IMAGING SYSTEM
20220047167 · 2022-02-17 ·

An optical system measures one or more physiological parameters with a wearable device that includes a light emitting diode (LED) source including a driver and a plurality of semiconductor sources that generate an output optical light. One or more lenses deliver a lens output light to tissue of a user. A detection system receives at least a portion of the lens output light reflected from the tissue and generates an output signal having a signal-to-noise ratio. The detection system comprises a plurality of spatially separated detectors and an analog to digital converter. The detection system increases the signal-to-noised ratio by comparing a first signal with the LEDs off to a second signal with the LEDs on. An imaging system including a Bragg reflector is pulsed and has a near infrared wavelength. A beam splitter splits the light into a sample arm and a reference arm to measure time-of-flight.

Appearance inspection device and blister packaging machine
11156560 · 2021-10-26 · ·

An appearance inspection device includes: a conveyance body having a surface and a rear face and conveyed in a predetermined direction; an illumination device that irradiates with predetermined light an inspection area through which a plurality of objects pass, wherein the objects are arranged at predetermined intervals on a first face that is one of the surface and the rear face; a plurality of imaging devices each of which takes, along a predetermined direction, an image of part of side faces of the objects located in the inspection area, wherein the predetermined direction is inclined to both the surface and the rear face; and a processor that inspects an appearance of the side faces of the objects based on image data obtained by the imaging device.

Monitoring dissolution of a dosage form in progress during dissolution by low coherence interferometry

A method of monitoring a property of a dissolution of an at least partially solid dosage form during a dissolution process is disclosed. The method includes at least partially dissolving the dosage form, and during the dissolution of the dosage form, simultaneously monitoring the property of the dissolution of the dosage form in progress by low coherence interferometry.

APPLICATION OF RAMAN SPECTROSCOPY FOR THE MANUFACTURE OF INHALATION POWDERS
20210293715 · 2021-09-23 · ·

The present invention generally relates to improved methods for the manufacture of inhalation powders. More particularly, aspects of the disclosure relate to methods for in-line monitoring of powder blending by Raman spectroscopy.

DEVICE AND METHOD FOR DETECTION OF COUNTERFEIT PHARMACEUTICALS
20210208063 · 2021-07-08 ·

A device (100) for measuring light transmission through a suspected counterfeit pharmaceutical tablet (102) includes a laser source (110) configured to emit a light transmission through the pharmaceutical tablet (102). A light detector (120) is included in the device (100) configured to receive the light transmission and measure an amount of light passed through the suspected counterfeit pharmaceutical tablet (102). The amount of light transmitted through the suspected counterfeit pharmaceutical tablet (102) is indicative of an authentic or counterfeit.

Systems and methods for identifying medicines deposited in a compartment of a pill box according to a prescription

The disclosure relates to a system for identifying medicines, comprising a first measurement device for identifying, from the top, at least one first medicine deposited in a compartment of a pill box and analysing at least one identifying characteristic of the first medicine; and a second measurement device for identifying, from the bottom, at least one second medicine deposited in the compartment of said pill box and analysing at least one identifying characteristic of the second medicine. The system comprises a device for comparing the characteristic of the first medicine and the characteristic of the second medicine, for determining at least one validated medicine and comparing the characteristic of the validated medicine with medicine signature characteristics. The system also comprises a validation device for obtaining an identified content for the compartment and comparing the identified content with a prescription. Methods for identifying and validating medicines are also disclosed.