The invention relates to a flow cell for absorption detection, in which a tube through which flow is to pass is held at its opposite ends in a supporting flange in each case and is suspended in a substantially cantilevered manner, the two supporting flanges being connected rigidly to each other in order to avoid stresses accidentally introduced into the tube.

The present invention describes a method involving measuring of water quality and/or detection of one or more substances in a water flow, said method involving the steps of using a sensor system comprising at least two electrodes, for sending frequency from at least one electrode and receiving a response from at least another electrode, wherein the method involves filtration over one or more frequency ranges in the response, to measure the impedance and using the impedance as an indicator of the water quality and/or for detection of one or more substances in the water flow.

System for measuring the composition of a multiphase fluid flow in a pipe, the multiphase flow containing a mixture of gas and liquid. The system comprising a first and a second sensor arrangement, wherein each sensor arrangement is adapted to measuring electrical characteristics (i.e. impedance) of the flow at a predetermined rate. The system also including an analysis unit being adapted to monitor the measured electrical characteristics from said first and second sensor arrangement and to detect occurrences of time periods involving a predetermined relationship between the measured characteristics, and during these periods assuming a liquid rich phase and calculating the composition based on the electrical characteristics.

System for measuring the composition of a multiphase fluid flow in a pipe, the multiphase flow containing a mixture of gas and liquid. The system comprising a first and a second sensor arrangement, wherein each sensor arrangement is adapted to measuring electrical characteristics (i.e. impedance) of the flow at a predetermined rate. The system also including an analysis unit being adapted to monitor the measured electrical characteristics from said first and second sensor arrangement and to detect occurrences of time periods involving a predetermined relationship between the measured characteristics, and during these periods assuming a liquid rich phase and calculating the composition based on the electrical characteristics.

A lateral flow assay device includes several markers, a color bar, and/or a grayscale on the housing of the lateral flow assay device. The markers are used to assist in focusing a mobile device's camera on the control line of the lateral flow assay device. The markers may be used to adjust the perspective of an image taken from the control line and the test line of the lateral flow assay device. The markers may be used to locate the images of the control line, the test line, the color bar, and/or the grayscale on the image. The image of the color bar and the grayscale may be used to adjust the colors and intensity of the image. The images of the test line and the control line may then be used to determine the test results of the lateral flow assay device.

A lateral flow assay device includes several markers, a color bar, and/or a grayscale on the housing of the lateral flow assay device. The markers are used to assist in focusing a mobile device's camera on the control line of the lateral flow assay device. The markers may be used to adjust the perspective of an image taken from the control line and the test line of the lateral flow assay device. The markers may be used to locate the images of the control line, the test line, the color bar, and/or the grayscale on the image. The image of the color bar and the grayscale may be used to adjust the colors and intensity of the image. The images of the test line and the control line may then be used to determine the test results of the lateral flow assay device.

A method of providing a dispense purified water stream from a water purification apparatus involving passing a water inlet stream through a first water purification station to provide a first internal purified water stream, passing the first internal purified water stream to an internal reservoir, and providing a second internal purified water stream from the reservoir, passing the second internal purified water stream into a recirculation loop, measuring the conductivity of the second internal purified water stream; passing the second internal purified water stream to a second water purification station to provide a third internal purified water stream passing the recirculated water return stream into the internal reservoir; calculating the purity of the first internal purified water stream using the measurement of the conductivity of the second internal purified water stream.

A method of providing a dispense purified water stream from a water purification apparatus involving passing a water inlet stream through a first water purification station to provide a first internal purified water stream, passing the first internal purified water stream to an internal reservoir, and providing a second internal purified water stream from the reservoir, passing the second internal purified water stream into a recirculation loop, measuring the conductivity of the second internal purified water stream; passing the second internal purified water stream to a second water purification station to provide a third internal purified water stream passing the recirculated water return stream into the internal reservoir; calculating the purity of the first internal purified water stream using the measurement of the conductivity of the second internal purified water stream.

Disclosed herein are apparatuses for nucleic acid sequencing, and methods of making and using such apparatuses. In some embodiments, the apparatus comprises a magnetic sensor array comprising a plurality of magnetic sensors, each of the plurality of magnetic sensors coupled to at least one address line, and a fluid chamber adjacent to the magnetic sensor array, the fluid chamber having a proximal wall adjacent to the magnetic sensor array. In some embodiments, a method of sequencing nucleic acid using the apparatus comprises (a) coupling a plurality of molecules of a nucleic acid polymerase to the proximal wall of the fluid chamber; (b) in one or more rounds of addition, adding, to the fluid chamber, (i) a nucleic acid template comprising a primer binding site and an extendable primer, and (ii) a first magnetically-labeled nucleotide precursor comprising a first cleavable magnetic label, a second magnetically-labeled nucleotide comprising a second cleavable magnetic label, a third magnetically-labeled nucleotide comprising a third cleavable magnetic label, and a fourth magnetically-labeled nucleotide comprising a fourth cleavable magnetic label; and (c) sequencing the nucleic acid template, wherein sequencing the nucleic acid template comprises, using the at least one address line, detecting a characteristic of at least a portion of the magnetic sensors in the magnetic sensor array, wherein the characteristic indicates which of the first, second, third, or fourth magnetically-labeled nucleotide precursors has been incorporated into the extendable primer. In some embodiments, a method of sequencing nucleic acid using the apparatus comprises (a) binding a nucleic acid strand to the proximal wall; (b) in one or more rounds of addition, adding, to the fluid chamber, (i) an extendable primer, and (ii) a plurality of molecules of a nucleic acid polymerase; (c) adding, to the fluid chamber, a first magnetically-labeled nucleotide precursor comprising a first cleavable magnetic label; and (d) sequencing the nucleic acid template, wherein sequencing the nucleic acid template comprises, using the at least one address line, detecting a characteristic of at least a first portion of the magnetic sensors in the magnetic sensor array, wherein the characteristic indicates that the first magnetically-labeled nucleotide precursor has bound to at least one molecule of the plurality of molecules of the nucleic acid polymerase or has been incorporated into the extendable primer. In some embodiments, a method of manufacturing a nucleic acid sequencing device having at least one fluid chamber configured to contain fluid comprises fabricating a first addressing line on a substrat

Disclosed herein are apparatuses for nucleic acid sequencing, and methods of making and using such apparatuses. In some embodiments, the apparatus comprises a magnetic sensor array comprising a plurality of magnetic sensors, each of the plurality of magnetic sensors coupled to at least one address line, and a fluid chamber adjacent to the magnetic sensor array, the fluid chamber having a proximal wall adjacent to the magnetic sensor array. In some embodiments, a method of sequencing nucleic acid using the apparatus comprises (a) coupling a plurality of molecules of a nucleic acid polymerase to the proximal wall of the fluid chamber; (b) in one or more rounds of addition, adding, to the fluid chamber, (i) a nucleic acid template comprising a primer binding site and an extendable primer, and (ii) a first magnetically-labeled nucleotide precursor comprising a first cleavable magnetic label, a second magnetically-labeled nucleotide comprising a second cleavable magnetic label, a third magnetically-labeled nucleotide comprising a third cleavable magnetic label, and a fourth magnetically-labeled nucleotide comprising a fourth cleavable magnetic label; and (c) sequencing the nucleic acid template, wherein sequencing the nucleic acid template comprises, using the at least one address line, detecting a characteristic of at least a portion of the magnetic sensors in the magnetic sensor array, wherein the characteristic indicates which of the first, second, third, or fourth magnetically-labeled nucleotide precursors has been incorporated into the extendable primer. In some embodiments, a method of sequencing nucleic acid using the apparatus comprises (a) binding a nucleic acid strand to the proximal wall; (b) in one or more rounds of addition, adding, to the fluid chamber, (i) an extendable primer, and (ii) a plurality of molecules of a nucleic acid polymerase; (c) adding, to the fluid chamber, a first magnetically-labeled nucleotide precursor comprising a first cleavable magnetic label; and (d) sequencing the nucleic acid template, wherein sequencing the nucleic acid template comprises, using the at least one address line, detecting a characteristic of at least a first portion of the magnetic sensors in the magnetic sensor array, wherein the characteristic indicates that the first magnetically-labeled nucleotide precursor has bound to at least one molecule of the plurality of molecules of the nucleic acid polymerase or has been incorporated into the extendable primer. In some embodiments, a method of manufacturing a nucleic acid sequencing device having at least one fluid chamber configured to contain fluid comprises fabricating a first addressing line on a substrat