Devices that includes a first portion, the first portion including at least one fluid channel; a fluid actuator; an analysis sensor disposed within the fluid channel; a conductivity sensor disposed within the fluid channel; and an introducer; a second portion, the second portion comprising: at least one well, the well containing at least one material, wherein one of the first or second portion is moveable with respect to the other, wherein the introducer is configured to obtain at least a portion of the material from the at least one well and deliver it to the fluid channel, and wherein the fluid actuator is configured to move at least a portion of the material in the fluid channel.

Devices that includes a first portion, the first portion including at least one fluid channel; a fluid actuator; an analysis sensor disposed within the fluid channel; a conductivity sensor disposed within the fluid channel; and an introducer; a second portion, the second portion comprising: at least one well, the well containing at least one material, wherein one of the first or second portion is moveable with respect to the other, wherein the introducer is configured to obtain at least a portion of the material from the at least one well and deliver it to the fluid channel, and wherein the fluid actuator is configured to move at least a portion of the material in the fluid channel.

Multiphase flow metering is provided. In one possible implementation, a multiphase flow measurement system includes at least one reference temperature sensor at a first position configured to measure a first temperature of a multiphase flow. The multiphase flow measurement system also includes at least one heated temperature sensor at a second position downstream of the reference temperature sensor configured to excite the multiphase flow and measure a second temperature of the multiphase flow.

Multiphase flow metering is provided. In one possible implementation, a multiphase flow measurement system includes at least one reference temperature sensor at a first position configured to measure a first temperature of a multiphase flow. The multiphase flow measurement system also includes at least one heated temperature sensor at a second position downstream of the reference temperature sensor configured to excite the multiphase flow and measure a second temperature of the multiphase flow.

A fluid property detecting device includes a detection portion configured to detect electric characteristics of a detection target fluid, a calculation portion configured to calculate a property value of the detection target fluid, and a storage portion configured to store the property value calculated by the calculation portion. The storage portion stores, in advance, as the reference detection value, the detection value of the electric characteristic of a reference fluid detected by the detection portion, and the calculation portion calculates the property value of the detection target fluid on the basis of a value obtained by subtracting the reference detection value from a detection value of the detection target fluid.

A medicament preparation system includes a disposable cartridge with a flow path. Various sensors may be placed on the cartridge to measure qualities of the fluid flowing through the flow path. The sensors are placed in precise locations using various approaches that make manufacturing of the cartridge efficient and repeatable. A drain line that is susceptible to fouling may be preattached and various approaches are used to remove or reduce the fouling. An elastomeric contact can also be present in the medical preparation system and used in a conductivity measurement subsystem.

A medicament preparation system includes a disposable cartridge with a flow path. Various sensors may be placed on the cartridge to measure qualities of the fluid flowing through the flow path. The sensors are placed in precise locations using various approaches that make manufacturing of the cartridge efficient and repeatable. A drain line that is susceptible to fouling may be preattached and various approaches are used to remove or reduce the fouling. An elastomeric contact can also be present in the medical preparation system and used in a conductivity measurement subsystem.

An electrical conductivity detector includes a cell through which a liquid flows, a measurement part for obtaining an electrical conductivity signal which is a current corresponding to an electrical conductivity of the liquid flowing through the cell, a phase adjustment value holder that holds a phase adjustment value which is a predetermined shift amount between a phase of the electrical conductivity signal and a phase of a measurement voltage applied to the cell by the measurement part, a BG subtraction signal generator configured to generate a BG subtraction signal for removing a background component included in the electrical conductivity signal obtained by the measurement part, the BG subtraction signal being adjusted to have a phase substantially identical to the phase of the electrical conductivity signal using the phase adjustment value held in the phase adjustment value holder, an addition part configured to add the electrical conductivity signal and the BG subtraction signal with each other, and a calculation part configured to calculate the electrical conductivity of the liquid flowing through the cell using a signal output from the addition part.

An electrical conductivity detector includes a cell through which a liquid flows, a measurement part for obtaining an electrical conductivity signal which is a current corresponding to an electrical conductivity of the liquid flowing through the cell, a phase adjustment value holder that holds a phase adjustment value which is a predetermined shift amount between a phase of the electrical conductivity signal and a phase of a measurement voltage applied to the cell by the measurement part, a BG subtraction signal generator configured to generate a BG subtraction signal for removing a background component included in the electrical conductivity signal obtained by the measurement part, the BG subtraction signal being adjusted to have a phase substantially identical to the phase of the electrical conductivity signal using the phase adjustment value held in the phase adjustment value holder, an addition part configured to add the electrical conductivity signal and the BG subtraction signal with each other, and a calculation part configured to calculate the electrical conductivity of the liquid flowing through the cell using a signal output from the addition part.

Described herein are cartridges and devices for operating said cartridges for analyzing a biological sample, such as a blood or saliva sample. Also described herein is an impedance sensor for analyzing a biological sample. Further described herein are methods of determining a cell count or detecting an analyte in a biological sample, which can include transporting the biological sample through a sensor comprising a channel or pore; applying an electrical current or voltage to the channel or pore; detecting an impedance within the channel or pore; and determining a cell count or detecting the analyte based on the detected impedance. Also described herein is an electrowetting electrode array that is configured to transport aqueous solutions using low voltage, such as about 50 volts or less. Further described herein are methods of transporting an aqueous liquid using electrowetting electrodes.