Disclosed are solid dressings for treating wounded tissue in mammalian patients, such as a human, comprising a haemostatic layer consisting essentially of a fibrinogen component and a fibrinogen activator, wherein the haemostatic layer(s) is cast or formed from a single aqueous solution containing the fibrinogen component and the fibrinogen activator. Also disclosed are methods for treating wounded tissue using these dressings and frozen compositions useful for preparing the haemostatic layer(s) of these dressings.

The invention relates to a wound dressing (2) for wound treatment in a damp environment, comprising a fiber fleece-based suction/irrigation body (4) in which super absorbent material is accommodated in a distributed manner, wherein the suction/irrigation body (4) is supplied with a salt-containing aqueous solution by the manufacturer, and comprising a packaging (6) forming the outer visible sides of the wound dressing, wherein the packaging (6) comprises a layer (9) made from a flat textile material on the side of the wound dressing facing the wound, wherein the layer (9) made from a flat textile material on the side facing the wound comprises an outer-side, partially and structurally applied atraumatically effective coating (22) having a degree of coverage of at most 70%, characterised in that the packaging (6) comprises a fiber fleece layer (12) on the side of the wound dressing facing away from the wound, which forms the outer visible side (14) of the wound dressing facing away from the wound, and in that a liquid-impermeable plastic film layer (16) is arranged on the side of said fiber fleece layer (12) facing the wound, and in that the fiber fleece layer (12), the plastic film layer (16), the suction/irrigation body (4) and the layer (9) made from flat textile material are not connected extensively to one another, but rather lie with the flat sides thereof loosely and movably against one another and are only connected with one another along the peripheral edges (18) of same by means of a joint connection.

The present application is concerned with an improved wound dressing for use in the treatment of skin wounds with some level of exudation, especially for use in those wounds which are infected or under risk of being infected by microorganisms.

This invention relates to a pharmaceutical preparation for the treatment of compromised tissue such as skin wounds and ulcers in humans and animals and a method of preparation. This is a multifunctional natural matrix meant for the treatment of compromised tissues which also relates to the anti-cancer transdermal patch for melanoma therapy. Further, the invention comprises for the treatment of Alzheimer's, and multiple sclerosis also. The composition consists of water-solubilized nano-sized formulation of non-aqueous solvent extract of phyto-pharmaceuticals in herbal, animal or synthetic biocompatible gel or on matrix coated or both. The composition is used as a topical device for the treatment of compromised tissues in its preferred embodiment.

A process for preparing a disinfecting wound dressing for the protection of wounds, such as burn wounds, ulcers and cuts, the process comprising the steps of providing a yarn-based substrate, subjecting a surface of the substrate to a plasma environment, thereby providing non-leaching and biocidal features to the substrate surface by exposing the substrate surface to an antimicrobial active compound reaction.

Described herein are wound dressings, methods for their production and components for use therein. Described herein are a knitted structure including a blend of gelling fibres and non-gelling fibres wherein the yarn includes at least 50% w/w gelling fibres, a three-dimensional textile material including gelling fibres, and a yarn including a blend of gelling and non-gelling fibres which may be used in their production, the knitted structure and three-dimensional textile material being suitable for use as wound dressings or as components of composite wound dressings. The wound dressings may be adapted for use in negative pressure wound therapy (NPWT). It has been found that the incorporation of gel-forming fibres provides a material which has a high absorbency, enabling good transfer of exudates away from a wound, which retains structural integrity, and which is non-adherent and easily removed from the wound.

An article of manufacture suitable for addressing a problem in a human body includes a material in sheet form including first and second adhesive-coated parts releasably retained on a cover layer. Each of the first and second adhesive-coated parts includes a support layer of synthetic microfiber fabric having a greater resistance to stretching in a first test direction than in a second test direction and an adhesive intermittent across the support layer. Each of the first and second adhesive-coated parts is elongated with straight sides and rounded end portions and is configured to be removable from the cover layer and adhered to an outer skin surface of the human body. The support layer allows the passage of moisture vapor, and the adhesive being intermittent across the support layer increases permeability.

A therapeutic article of manufacture suitable for adhesive application to the skin of a user includes an elongate support layer formed of a single layer of woven fabric. The woven fabric has a ratio of elongation in percent to tensile strength (lb/in-width) that is less than 0.9 in only one of two test directions, where elongation, tensile strength, and test directions are determined under test conditions specified in ASTM (American Society for Testing and Materials) D3759. The article of manufacture additionally includes an adhesive intermittent across the support layer and a removable cover layer releasably retained on the adhesive.

A method of treating microbial infections that entails producing a space over the infected site by covering such site with an impermeable material and then filling such space with an antimicrobial material (in the form of a solution, cream, gel, colloid, etc) comprising an efflux pump inhibitor soluble in a non-polar solvent is provided. The antimicrobial material can also be applied in multiple other ways such as a cream or released from a band-aid or gauze. Such treatment method may also be used with newly discovered antibiotics.

The composite wound dressing apparatus promotes healing of a wound via the use of a vacuum pump. The vacuum pump applies a vacuum pressure to the wound to effectively draw wound fluid or exudate away from the wound bed. The vacuum pump is tethered to the wound dressing and is portable, preferably, carried by the patient in a support bag, which permits patient mobility. Moreover, the patient does not need to be constrained for any period of time while exudate is being removed from the wound.