An opening sealing structure is provided with a housing, a step portion, a seal cap, an elastic sealing member, and a cap fixture. The housing has a cap mounting portion having a a cylindrical shape. The step portion is provided on the outer peripheral surface of the cap mounting portion and has a side surface facing the base end side of the cap mounting portion. The side surface of the step portion is inclined along the circumferential direction of the cap mounting portion from the tip end side of the cap mounting portion to the base end side and its inclination angle is smaller on the base end side of the cap mounting portion than on the tip end side. The cap fixture has a cap holding portion movably engaged with the seal cap in a circumferential direction of its outer peripheral surface and an elastic portion connected to the cap holding portion. The elastic portion is provided with a protrusion which engages the side surface of the step portion.

An opening sealing structure is provided with a housing, a step portion, a seal cap, an elastic sealing member, and a cap fixture. The housing has a cap mounting portion having a a cylindrical shape. The step portion is provided on the outer peripheral surface of the cap mounting portion and has a side surface facing the base end side of the cap mounting portion. The side surface of the step portion is inclined along the circumferential direction of the cap mounting portion from the tip end side of the cap mounting portion to the base end side and its inclination angle is smaller on the base end side of the cap mounting portion than on the tip end side. The cap fixture has a cap holding portion movably engaged with the seal cap in a circumferential direction of its outer peripheral surface and an elastic portion connected to the cap holding portion. The elastic portion is provided with a protrusion which engages the side surface of the step portion.

A chromatograph device which makes it possible to suppress a carry-over phenomenon. A sample injection unit for collecting a liquid sample and injecting a predetermined amount of liquid sample into a mobile phase; a sample introduction tube a distal end section of which has a needle formed therein and a terminal end section of which is connected to the sample injection unit; a separation column which is coupled via a column coupling tube to the sample injection unit, and through which the mobile phase where the liquid sample has been injected passes; and a detection unit that is connected to the separation column and detects a component in the liquid sample. The column coupling tube is provided with an ultrasonic vibrator for vibrating the tube.

A chromatograph device which makes it possible to suppress a carry-over phenomenon. A sample injection unit for collecting a liquid sample and injecting a predetermined amount of liquid sample into a mobile phase; a sample introduction tube a distal end section of which has a needle formed therein and a terminal end section of which is connected to the sample injection unit; a separation column which is coupled via a column coupling tube to the sample injection unit, and through which the mobile phase where the liquid sample has been injected passes; and a detection unit that is connected to the separation column and detects a component in the liquid sample. The column coupling tube is provided with an ultrasonic vibrator for vibrating the tube.

A sample vaporization unit for vaporizing a sample injected from a syringe needle while supplying a carrier gas into a column is provided with a pipe, a heat conductive member, and a heater. The column is inserted into the pipe. The heat conductive member is provided along the outer circumference of the pipe. The heater is provided along the outer circumference of the heat conductive member. The heat conductive member is in line contact with the pipe along the axial direction in which the column extends at a plurality of circumferential locations on the outer circumferential surface of the pipe.

A sample vaporization unit for vaporizing a sample injected from a syringe needle while supplying a carrier gas into a column is provided with a pipe, a heat conductive member, and a heater. The column is inserted into the pipe. The heat conductive member is provided along the outer circumference of the pipe. The heater is provided along the outer circumference of the heat conductive member. The heat conductive member is in line contact with the pipe along the axial direction in which the column extends at a plurality of circumferential locations on the outer circumferential surface of the pipe.

Disclosed is a separation column for micro gas chromatography, having superior separation performance and including a microchannel formed on a substrate and having a serpentine shape, and bumps formed on the surface of the microchannel, wherein the bumps are alternately disposed to face each other on the surface of the microchannel. In the separation column for micro gas chromatography, a sufficient pressure drop occurs, and thus an M interaction between a gas mixture to be analyzed and a stationary phase in the column sufficiently takes place, whereby individual gas components are efficiently separated from the gas mixture, discharged from the column, and detected.

Disclosed is a separation column for micro gas chromatography, having superior separation performance and including a microchannel formed on a substrate and having a serpentine shape, and bumps formed on the surface of the microchannel, wherein the bumps are alternately disposed to face each other on the surface of the microchannel. In the separation column for micro gas chromatography, a sufficient pressure drop occurs, and thus an M interaction between a gas mixture to be analyzed and a stationary phase in the column sufficiently takes place, whereby individual gas components are efficiently separated from the gas mixture, discharged from the column, and detected.

The invention concerns a method for preparing a sample to be introduced in a chromatographic analysis system from the headspace of a vial, by introducing a pressurized inert gas in said headspace, controlling the pressure or flow, and subsequently by discharging said pressure from the headspace through a loop having constant volume and through a discharge duct provided with a valve, the discharge duct branching with respect to the feed duct. To eliminate the drawbacks of the known methods, during the step of discharging the pressure, the feed duct is kept open and the pressure in said loop is controlled by detecting the feed and/or discharge pressure.

A system and method for utilizing a carbide-derived carbon (CDC) fiber in solid-phase micro extraction. Optically pumping the carbide-derived carbon (CDC) fiber, as compared to using thermal desorption, enhances performance of the system. CDC provides for a broad based sorbent that is insensitive to high humidity. Optical pumping may be done axially or radially on a modified gas chromatography needle. In some cases, staged, or pulsed, optical pumping is used to drive off solvent or other lower boiling compounds first and then the desorption of the remaining analytes is cleaner and the instrumentation is less likely to be overloaded.