A method for collecting a sample for sample analysis includes drawing a first portion of the sample into a sample storage portion of a chromatography system while the chromatography system is in a first configuration. The method further comprising switching the chromatography system to a second configuration; sealing an end of a sample pick-up needle and draining a portion of a liquid from the second tubing; switching the chromatography system to a third configuration; drawing a second portion of the sample into the sample storage portion of the chromatography system; switching the chromatography system to an injection configuration; and fluidly connecting the sample storage portion to the chromatography column and supplying the first portion of the sample and the second portion of the sample from the sample storage portion to the chromatography column.

A method for collecting a sample for sample analysis includes drawing a first portion of the sample into a sample storage portion of a chromatography system while the chromatography system is in a first configuration. The method further comprising switching the chromatography system to a second configuration; sealing an end of a sample pick-up needle and draining a portion of a liquid from the second tubing; switching the chromatography system to a third configuration; drawing a second portion of the sample into the sample storage portion of the chromatography system; switching the chromatography system to an injection configuration; and fluidly connecting the sample storage portion to the chromatography column and supplying the first portion of the sample and the second portion of the sample from the sample storage portion to the chromatography column.

Valve with two-piece stator assembly for use with liquid chromatography or other analytical systems. A separate and removable stator plate is provided with a mounting device to provide a two-piece stator assembly. The mounting device is adapted on one side to engage and contact the stator plate, and on the other side includes a plurality of ports for fluidic connections which are in fluid communication with fluid passageways in the stator plate.

Valve with two-piece stator assembly for use with liquid chromatography or other analytical systems. A separate and removable stator plate is provided with a mounting device to provide a two-piece stator assembly. The mounting device is adapted on one side to engage and contact the stator plate, and on the other side includes a plurality of ports for fluidic connections which are in fluid communication with fluid passageways in the stator plate.

Systems and methods are described to maintain a liquid sample segment of a sample transmitted through a transfer line from a remote sampling to an analysis system. A system embodiment includes, but is not limited to, a sample transfer line configured to transport a liquid sample from a remote sampling system via gas pressure; a sample loop fluidically coupled with the sample transfer line, the sample loop configured to hold a sample fluid; and a backpressure chamber fluidically coupled with a gas pressure source and with the sample transfer line, the backpressure chamber configured to supply a backpressure against the liquid sample during transport through the sample transfer line.

An injector is configured for injecting a fluidic sample from an injector path into a mobile phase in a separation path between a fluid drive and a sample separation unit of a sample separation device. The injector includes a control unit configured for generating a first overpressure in a blocked first partial path of the injector path by a first pressure source, for generating a second overpressure in a blocked second partial path of the injector path by a second pressure source, for subsequently fluidically coupling the first partial path with the second partial path for generating an expansion stroke for releasing a gas bubble in the injector path, and for rinsing the released gas bubble from the injector path.

An injector is configured for injecting a fluidic sample from an injector path into a mobile phase in a separation path between a fluid drive and a sample separation unit of a sample separation device. The injector includes a control unit configured for generating a first overpressure in a blocked first partial path of the injector path by a first pressure source, for generating a second overpressure in a blocked second partial path of the injector path by a second pressure source, for subsequently fluidically coupling the first partial path with the second partial path for generating an expansion stroke for releasing a gas bubble in the injector path, and for rinsing the released gas bubble from the injector path.

A sample delivery system for liquid chromatography is provided. The sample delivery system includes: a sample receptacle; a sample aspiration cannula for aspirating a sample located in the sample receptacle, the sample aspiration cannula being directed using a drive in a direction towards the sample receptacle so that a tip at a distal end of the sample aspiration cannula is immersed in the sample; and a guide element for the sample aspiration cannula provided above the sample receptacle, the guide element being designed as a washing device. The sample aspiration cannula can be retracted using the drive at least so far from the sample receptacle such that the distal end of the sample aspiration cannula may be cleaned in the washing device.

A sample delivery system for liquid chromatography is provided. The sample delivery system includes: a sample receptacle; a sample aspiration cannula for aspirating a sample located in the sample receptacle, the sample aspiration cannula being directed using a drive in a direction towards the sample receptacle so that a tip at a distal end of the sample aspiration cannula is immersed in the sample; and a guide element for the sample aspiration cannula provided above the sample receptacle, the guide element being designed as a washing device. The sample aspiration cannula can be retracted using the drive at least so far from the sample receptacle such that the distal end of the sample aspiration cannula may be cleaned in the washing device.

Apparatus and a method are provided for bringing a well-fluid sample in a well through a sampling device which is in fluid communication with the apparatus. The apparatus includes: a dump chamber for receiving the well-fluid sample; a first hydraulic piston arranged in a first cylinder housing; a second hydraulic piston arranged in a second cylinder housing; a piston rod for mechanically connecting the first piston to the second piston to form a piston arrangement, the dump chamber being defined by the first piston and a portion of the first cylinder housing. The apparatus further includes at least one holding device arranged to switch between an active position, in which the piston arrangement is held fixed against movement, and an inactive position, in which the piston arrangement is allowed a movement relative to the cylinder housings.