A portable gas analysis device having a separating column and a detector. The separating column is composed as a multi-capillary unit from parallel individual capillaries and, depending on the length, is bent into a compact shape, preferably even wound into multiple turns. A thermally conductive casing and a thermal stabilizing device are provided for the multi-capillary unit. The thermal stabilizing device comprises a temperature sensor, a heating element and control electronics. The casing protects the sensitive multi-capillary unit from mechanical actions; it acts as a protective space. The temperature-controlled casing also forms a space in which uniform and controlled conditions prevail and which in particular is isolated from the temperature and humidity of the environment, allowing reliable measurements outside a laboratory environment, in the field. This double effect of the casing for the capillaries in conjunction with the compact dimensions forms the true essence of the invention.

A portable gas analysis device having a separating column and a detector. The separating column is composed as a multi-capillary unit from parallel individual capillaries and, depending on the length, is bent into a compact shape, preferably even wound into multiple turns. A thermally conductive casing and a thermal stabilizing device are provided for the multi-capillary unit. The thermal stabilizing device comprises a temperature sensor, a heating element and control electronics. The casing protects the sensitive multi-capillary unit from mechanical actions; it acts as a protective space. The temperature-controlled casing also forms a space in which uniform and controlled conditions prevail and which in particular is isolated from the temperature and humidity of the environment, allowing reliable measurements outside a laboratory environment, in the field. This double effect of the casing for the capillaries in conjunction with the compact dimensions forms the true essence of the invention.

The present invention addresses to an automated gas injection system in vials with rubber septa, for simultaneous injection of gas in 24 or more positions, with injection pressure control and/or overpressure detection, applied to mass spectrometry analyses and/or gas chromatography. The present invention can be used, for example, in isotopic analyses of geological materials in equipment with carbonate extraction units, in the cleaning and decontamination of tubes to be used in isotopic or chromatographic analyses, and in the removal of contaminants from steam drag or by continuous flow, or coming from the free space of vials or tubes in the analyses of organic and inorganic materials.

The application of this invention allows reducing the current times of routine purge (flush) of at very least 3 minutes for every 2 positions (72 positions in total and final time of 108 minutes, in a batch of samples) to a total of 96 positions in 3 minutes, with a reduction of 12 times or more in the flush time, which implies greater analytical capacity to the laboratory, lower external costs of sending samples, less time to obtain results, with technology that is easy to implement in universities and research centers in general, in addition to increasing the lifespan of rubber septa.

Micro gas chromatographic devices are provided having a microfluidic separation column and a plurality of capillaries where the capillaries have been independently configured in terms of the capillary length, capillary width, the packing density and packing geometry of the capillary using one or more micro pillars, the tortuosity of the capillary path, and the presence and identity of the stationary phase for use in micro gas chromatographic separation of complex mixtures of compounds. Through the plurality of capillaries, the devices are capable of discriminating between complex samples even in instances where complete separation of the components is not possible. Methods of fabrication and methods of use of the devices are also provided. The devices can be readily fabricated using known techniques. The devices can be used for the analysis of complex mixtures of compounds containing tens or hundreds of compounds in which just a few differ in presence or concentration.

Micro gas chromatographic devices are provided having a microfluidic separation column and a plurality of capillaries where the capillaries have been independently configured in terms of the capillary length, capillary width, the packing density and packing geometry of the capillary using one or more micro pillars, the tortuosity of the capillary path, and the presence and identity of the stationary phase for use in micro gas chromatographic separation of complex mixtures of compounds. Through the plurality of capillaries, the devices are capable of discriminating between complex samples even in instances where complete separation of the components is not possible. Methods of fabrication and methods of use of the devices are also provided. The devices can be readily fabricated using known techniques. The devices can be used for the analysis of complex mixtures of compounds containing tens or hundreds of compounds in which just a few differ in presence or concentration.

The invention relates to a system and micro monitor apparatus, a space-, time-, and cost-efficient device to concentrate, identify, and quantify organic compounds in gas environments. The invention further relates to a method centered on gas chromatography for identifying and quantifying organic compounds in gas environments, using air as the carrier gas, without the need for a compressed pre-bottled purified carrier gas.

The invention relates to a system and micro monitor apparatus, a space-, time-, and cost-efficient device to concentrate, identify, and quantify organic compounds in gas environments. The invention further relates to a method centered on gas chromatography for identifying and quantifying organic compounds in gas environments, using air as the carrier gas, without the need for a compressed pre-bottled purified carrier gas.

An automated system for lipid exchange-mass spectrometry, e.g., measuring affinity of a membrane protein for lipids. The automated systems herein can measure the specificity of membrane protein-lipid interactions, detect remodeling of the membrane environment, and determine optimal lipid composition for membrane proteins.

An automated system for lipid exchange-mass spectrometry, e.g., measuring affinity of a membrane protein for lipids. The automated systems herein can measure the specificity of membrane protein-lipid interactions, detect remodeling of the membrane environment, and determine optimal lipid composition for membrane proteins.

A first attachment portion to which a packed column is attachable and a second attachment portion to which a chip column is attachable are housed in a column oven. Designation of a temperature of the column oven is received by a designated temperature receiver. In a case in which the chip column is not attached to the second attachment portion, an upper limit temperature of the column oven is set to a first temperature by a setter. An upper limit temperature of the column oven is set to a second temperature lower than the first temperature in a case in which the chip column is attached to the second attachment portion. A temperature of the column oven is adjusted to a received temperature by a temperature adjuster in a case in which the received temperature is equal to or lower than an upper limit temperature.