The present invention relates to a method of operating a fluidic system, wherein the fluidic system comprises a fluidic resistive element, wherein the method comprises a defined volume flow step, wherein in the defined volume flow step, a defined volume of a fluid is forced to flow out of the fluidic resistive element, wherein the defined volume is the fluid flowing out of the fluidic resistive element in a first time interval defined by a time t.sub.start and a time t.sub.end, wherein the defined volume flow step comprises: at the time t.sub.start, switching the system from a first operating state to a second operating state, to bring a pressure in the fluidic resistive element from a first pressure value to a second pressure value, the second pressure value exceeding the first pressure value, and at a time t.sub.reduce, which is after the time t.sub.start and not later than the time t.sub.end, switching the system to a third operating state to bring the pressure in the fluidic resistive element to a third pressure value, the third pressure value being below the second pressure value. The present invention also relates to a corresponding system and a corresponding computer program product.

Various approaches preparing Cannabis flower samples for analysis of cannabinoid content, the method comprising the steps of weighing the sample in a portable or benchtop balance; adding, to a container, the weighed sample and a solvent; agitating the vial and thereafter extracting a liquid component therefrom; and analytically analyzing the sample using the solvent based on the weight and a volume of the extracted liquid.

Various approaches preparing Cannabis flower samples for analysis of cannabinoid content, the method comprising the steps of weighing the sample in a portable or benchtop balance; adding, to a container, the weighed sample and a solvent; agitating the vial and thereafter extracting a liquid component therefrom; and analytically analyzing the sample using the solvent based on the weight and a volume of the extracted liquid.

An organic solvent containing liquid that does not include a component to be detected by a detector is used as a first solvent, and an organic solvent containing liquid that includes the component to be detected and is adjusted to have a concentration of an organic solvent that prevents a separation column from actually holding the component to be detected is used a second solvent. Further, a mobile phase is sent while a setting value of a concentration of the second solvent in the mobile phase is changed over time with the separation column provided on an analysis flow path, and an actual concentration of the second solvent in the mobile phase is found based on a detection signal of the detector when the mobile phase is sent at each setting value.

An organic solvent containing liquid that does not include a component to be detected by a detector is used as a first solvent, and an organic solvent containing liquid that includes the component to be detected and is adjusted to have a concentration of an organic solvent that prevents a separation column from actually holding the component to be detected is used a second solvent. Further, a mobile phase is sent while a setting value of a concentration of the second solvent in the mobile phase is changed over time with the separation column provided on an analysis flow path, and an actual concentration of the second solvent in the mobile phase is found based on a detection signal of the detector when the mobile phase is sent at each setting value.

Methods and system for identifying and quantifying antibody fragments and identifying the site of fragmentation on an antibody are provided herein.

The present invention relates to a liquid feeding apparatus capable of feeding a liquid with high accuracy. The liquid feeding apparatus includes a liquid feeder having a downstream side, a plunger, and a cylinder that is configured for aspirating and discharging a solvent when a plunger slides. The liquid feeding apparatus further includes a pressure sensor for the solvent to be discharged, a selector valve configured to switch between a plurality of solvents to be aspirated and discharged, and a controller configured to control the liquid feeder and the selector valve. The controller controls the selector valve in synchronization with an aspiration operation of the plunger so that a mixing ratio of the solvents changes, controls the plunger to cause the plunger to operate at first and second accelerations that are different from each other, and suppresses a fluctuation of the solvent to be aspirated by the plunger.

The present invention relates to a liquid feeding apparatus capable of feeding a liquid with high accuracy. The liquid feeding apparatus includes a liquid feeder having a downstream side, a plunger, and a cylinder that is configured for aspirating and discharging a solvent when a plunger slides. The liquid feeding apparatus further includes a pressure sensor for the solvent to be discharged, a selector valve configured to switch between a plurality of solvents to be aspirated and discharged, and a controller configured to control the liquid feeder and the selector valve. The controller controls the selector valve in synchronization with an aspiration operation of the plunger so that a mixing ratio of the solvents changes, controls the plunger to cause the plunger to operate at first and second accelerations that are different from each other, and suppresses a fluctuation of the solvent to be aspirated by the plunger.

Methods of assessing purity of cytisine using gradient chromatography at multiple wavelengths is provided herein.

Methods of assessing purity of cytisine using gradient chromatography at multiple wavelengths is provided herein.