Systems and methods for inline and automatic dilution of chemicals of interest for speciation and subsequent analysis by ICP spectrometry are described. A system embodiment includes a first valve to receive a sample into a holding loop; a plurality of syringe pumps coupled to the first valve to deliver an inline diluted sample from the first valve; and a second valve coupled to the first valve to receive the inline diluted sample from the first valve into a sample holding loop coupled to the second valve, the second valve configured to couple to at least one of an eluent source or a carrier fluid source to receive at least one of an eluent fluid or a carrier fluid to transfer the inline diluted sample from the sample holding loop to a speciation column to separate one or more species from the inline diluted sample.

A darkroom type security inspection apparatus and a method of performing an inspection using the darkroom type security inspection apparatus. An apparatus includes a housing constituting a closed darkroom, and assemblies disposed inside the housing. The assemblies disposed inside the housing include: a sample collecting unit configured to collect a sample, a conveyor unit, and a X-ray detection unit to detect a position of the objected to be inspected, wherein the X-ray detection unit is configured to determine the position of the objected to be inspected within the sampling assembly so that the object to be inspected together with the conveyor unit is conveyed to an expected position; and a sample processing assembly, wherein the assemblies disposed inside the housing are communicated by fittings or connectors.

The present invention relates to a method for the detection and quantification of fosfomycin and impurities and/or degradation products thereof in samples of fosfomycin or a pharmaceutically acceptable salt thereof or in pharmaceutical compositions comprising fosfomycin or a pharmaceutically acceptable salt thereof. The present invention further relates to a process for manufacturing fosfomycin, or a pharmaceutically acceptable salt thereof having a specified purity degree, as well as to the fosfomycin or a pharmaceutically acceptable salt thereof as obtained. The present invention further relates to a process for manufacturing a pharmaceutical composition comprising fosfomycin or a pharmaceutically acceptable salt thereof and at least one pharmaceutically acceptable excipient having a specified purity degree, as well as to the pharmaceutical composition as obtained.