A system for treating a linear wound on a patient has a closing dressing bolster for placing on the patient's epidermis over the linear wound, a sealing subsystem for providing a seal over the closing dressing bolster and the patient, and a reduced-pressure subsystem for delivering reduced pressure to the sealing subsystem. The sealing subsystem and reduced pressure subsystem are operable to deliver reduced pressure to the closing dressing bolster. The closing dressing bolster is operable under reduced pressure to develop a inward closing. The closing dressing bolster may include one or more closing members on each side of a center wound area to create the inward closing when under reduced pressure. A compressive force may also be developed. Other systems and methods are presented.

This invention relates to a pharmaceutical preparation for the treatment of compromised tissue such as skin wounds and ulcers in humans and animals and a method of preparation. This is a multifunctional natural matrix meant for the treatment of compromised tissues which also relates to the anti-cancer transdermal patch for melanoma therapy. Further, the invention comprises for the treatment of Alzheimer's, and multiple sclerosis also. The composition consists of water-solubilized nano-sized formulation of non-aqueous solvent extract of phytopharmaceuticals in herbal, animal or synthetic biocompatible gel or on matrix coated or both. The composition is used as a topical device for the treatment of compromised tissues in its preferred embodiment.

A wound dressing includes an elastic foam layer, a drape layer, and superabsorbent projections. The elastic foam layer is configured to engage a wound bed and has a first side and a second side, the second side configured to face the wound bed. The drape layer also has a first side and a second side, the second side configured to face the first side of the elastic foam layer. The elastic foam layer also has a plurality of superabsorbent projections (nodules, dots, bumps, lumps, islands, protuberances) fixed to and extending from the first side of the elastic foam layer towards the second side of the drape layer.

An apparatus for promoting circulation through a subcutaneous lymph vascular network may comprise a first manifold layer, a second manifold layer coupled to the first manifold layer, and a cover layer coupled to the second manifold layer. The first manifold may have a first stiffness, and the second manifold may have a second stiffness greater than the first stiffness. In some embodiments, the apparatus may additionally have a fluid interface configured to fluidly couple at least one of the first manifold layer and the second manifold layer to a fluid conductor through the cover layer. The fluid conductor may be coupled to or configured to be coupled to a source of negative pressure.

The disclosed technology relates to a wound dressing comprising a vertically lapped material. The disclosed technology further relates to methods and uses of the wound dressing.

Fibrin Sealant products are used for topical hemostasis and tissue adherence. They are composed of two main reagents, fibrinogen and thrombin. When mixed in solution fibrinogen is converted to fibrin upon the addition of activated thrombin. Therefore typically these two components are stored separately in a lyophilized or liquid state, and mixed, upon or immediately before, application to a patient. While effective, these products require significant preparation that must take place immediately before application, thus delaying treatment and limiting the use of these haemostatic products to the treatment of mild forms of low pressure and low volume bleeding. Attempts to eliminate this delay and expand the usefulness and effectiveness of these products have resulted in products produced by processes that require the separation of these components and their deposition in distinct layers within the product. The processes described herein permit the mixing of fibrinogen and thrombin during product manufacture, without excessive fibrin formation. The resulting pre-mixed fibrin sealant material can then be stored in either a frozen or dried state, or suspended in a non-aqueous environment. Activation of the material to form therapeutic fibrin sealant is accomplished by permitting the product to thaw (if frozen) or by the addition of water or other aqueous fluid, including blood, or other bodily fluids, if dried or suspended in a non-aqueous environment. The resulting material can be used to make a product in which a pre-mixed form of activatable fibrin sealant is a desired component.

Systems, apparatuses, and methods for providing negative pressure to a tissue site are disclosed. Illustrative embodiments may include an apparatus or system comprising a dressing for treating a tissue site with negative pressure. For example, the dressing may comprise or consist essentially of a manifold and a contact layer. In some embodiments, the manifold may have a tubular shape with a central axis. The contact layer may comprise a polymer film completely or substantially enclosing the manifold in some examples. In further embodiments, the dressing may comprise a plurality of fluid restrictions in the contact layer, the fluid restrictions configured to open or expand in response to a pressure gradient across the polymer film.

Disclosed and described herein are systems and methods energy generation from fabric electrochemistry. An electrical cell is created when electrodes (cathodes and anodes) are printed on or otherwise embedded into fabrics to generate DC power when moistened by a conductive bodily liquid such as sweat, wound, fluid, etc. The latter acts, in turn, as the cell's electrolyte. A singular piece of fabric can be configured into multiple cells by dividing regions of the fabric with hydrophobic barriers and having at least one anode-cathode set in each region. Flexible inter-connections between the cells can be used to scale the generated power, per the application requirements.

The present invention discloses a tubeless energy drainage device for trauma, pertaining to the field of tubeless drainage technology, especially relating to a tubeless energy drainage device for trauma. The device includes energy transmission carriers, lead wires, and a frequency electrical energy generator. The frequency energy resonance generator transmits electrical energy to the energy transmission carriers, activates metal potassium ions on the energy transmission carriers, and creates resonance through conduction of metal ions in a wound covering layer and changing frequency of a wound, thereby achieving retrograde drainage of the wound's own sinus in a drainage area. The device disclosed by the present invention is of great significance for the rapid and full drainage of intractable wounds and battlefield wounds, and the drainage, healing, and pain relief of minute wound fistulas that cannot be tubed.

The present disclosure provides a magnetic dressing and a preparation method and use thereof, belonging to the technical field of pharmaceutical preparations. The magnetic dressing includes a magnetic layer, a drug-loading layer, and a protective layer that are stacked in sequence, where the magnetic layer includes polyvinyl alcohol, gluten, and iron particles. In the present disclosure, a swallowed magnetic dressing is controlled by an external magnetic field, and the magnetic dressing is moved to a pathological position by changing a direction of the external magnetic field; after the external magnetic field is removed, the magnetic dressing changes from a ring to a sheet, thereby completing attachment of an entire lesion surface to complete treatment by autonomous drug release.