A chromatography system includes a chromatogram modeling device for synthesizing a modeled reference chromatogram, and an evaluation device for evaluating operation conditions of a chromatography device based on the modeled reference chromatogram.

The present invention relates to a method for providing information from a fraction collector in a liquid chromatography system, the system comprising a column, at least one reservoir for containing a fluid, at least one pump connected to said reservoir, a column arranged to receive an input from the reservoir, a measuring device for performing measurements on a fluid output from the column, and a fraction collector for receiving said fluid output in a plurality of receiving vessels, wherein the method comprisesdetermining at least one parameter of the fraction collector, andproviding information of said parameter on a display in the form of a graphical representation.

A chromatographic data system processing apparatus includes a standard sample time table for prestoring a first retention time and a first allowable width of each peak of specific components of a standard sample, a determination unit for determining whether a number of peaks coincides with a specified number when a peak cannot be identified, an alteration unit for altering the standard sample time table by increasing the first allowable width of a specific component to an altered allowable width, an identification unit for identifying the peaks based on the altered standard sample time table when all peaks fall within a range of the altered allowable width, and a setting unit for acquiring an actually-measured retention time of the peaks, and setting a measurement sample time table based on the actually-measured retention time and a second allowable width when the peaks are identified based on the altered standard sample time table.

A method of performing experiments on samples may include receiving criteria defining a starting state for performing an experiment in a system including a scientific instrument; determining whether the starting state is established in the system; and, responsive to the starting state being established, allowing the experiment, that analyzes a sample using the scientific instrument, to proceed. Determining whether the starting state is established may include automated monitoring of at least one parameter for at least one data channel, and determining whether all such parameters simultaneously meet associated conditions of the criteria for specified time periods. The method may include automatically monitoring the system and re-establishing the starting state prior to performing each of one or more subsequent experiments. The method may include automatically monitoring and establishing a second starting state prior to performing each of one or more additional experiments.

Disclosed herein are scientific instrument support systems, as well as related methods, computing devices, and computer-readable media. For example, in some embodiments, a chromatography instrument support apparatus may include: first logic to receive, from an imaging device, image data regarding chromatography instrumentation; second logic to determine a state of the chromatography instrumentation by processing the imaging device through a machine-learning computational model; and third logic to display the state of the chromatography instrumentation.

An apparatus for deriving an operation mode from a first fluidic device to a second fluidic device, wherein the first fluidic device has a first target operation mode representing a desired behavior of the first fluidic device and has a first real operation mode representing the actual behavior of the first fluidic device, wherein the second fluidic device has a second target operation mode representing a desired behavior of the second fluidic device and has a second real operation mode representing the actual behavior of the second fluidic device, the apparatus comprising a first determining unit configured for determining the first real operation mode based on the first target operation mode and based on a preknown parameterization of the first fluidic device, and a second determining unit configured for determining the second target operation mode based on the determined first real operation mode and based on a preknown parameterization of the second fluidic device.

An analyzer control system 20 for monitoring and controlling an analyzer 20 includes: a plurality of sensors for detecting the condition of each component of the analyzer; a potential problem inference section 23 for receiving detection results obtained with all or part of the sensors and for inferring whether or not the analyzer is in a potentially problematic condition; and a potential problem display section 32 for showing, on a display screen, information on the potentially problematic condition. The potentially problematic condition is neither a condition in which the analysis data being collected by the analyzer are unusable, nor a condition which requires deactivation of the analyzer; it is a condition in which the analyzing operation may be continued for the time being, although the analyzer is likely to soon fall into the aforementioned situations if the operation is further continued. The already collected data can be properly used.

The disclosure is directed to a system and method for control of at least one bioreactor, other cell cultivation-related equipment, and systems containing any combination of these in a plant. For example, a Plant-Wide Control System (PWCS) or a Process Control System (PCS) may be divided into three main components: hardware (including operating systems, such as a controller communicating with one or more servers of a network associated with the PWCS, (2) software (such as a control module) for performing control, and (3) one or more instrument control loops, which may be used by the software to maintain certain process values. Moreover, a Height Equivalent of a Theoretical Plate (HETP) value and an asymmetry factor may be determined based on real-time analysis on a chromatography column, using PWCS components.

A waveform-analyzing device includes a trained-model storage section (44) for a trained model which detects a peak from a waveform. The model is constructed by machine learning using reference waveform data as teaching data. Each reference waveform has a different baseline shape and a known position of a peak portion including an overlap peak, with tailing processing, complete separation or vertical partitioning related to this peak. For an input of measurement data, the model outputs an index which represents a single-peak, overlap-peak or non-peak portion and to which the tailing processing, complete separation or vertical partitioning is related as a peak separation technique. A n index outputter (55-57) inputs analysis-target data into the model to obtain an output of the index which represents a single-peak, overlap-peak or non-peak portion and to which the tailing processing, complete separation or vertical partitioning is related as the technique for separating the overlap-peak portion.

A computer-implemented method is provided for controlling a chromatography system that is configured to physically perform and/or simulate a chromatography process. The method comprises obtaining, from the chromatography system, a current state of the chromatography system, the current state including one or more values of one or more state parameters, the one or more state parameters including one or more quantities of one or more substances present in the chromatography system, and determining one or more values of one or more control parameters for the chromatography system according to a policy that is configured to map the current state to a corresponding action representing the one or more values of the one or more control parameters.