This invention relates to a multi-layer wound site dressing specifically designed to treat chronic wounds and simultaneously block external pathogens from infecting the wound site from the environment. The said wound dressing comprises five layers; each layer performs a specific functionality in healing and protecting the wound site. The said layers of wound care dressing comprise (i) a permeable non-adherent woven or non-woven membrane in contact with wound site, (ii) a nanofibrous composite layer made of superabsorbent, activated carbon and a polymer (iii) a hydrophobic insulating membrane which is permeable to air with an adhesive edge, (iv) a nanofibrous membrane made of polymer and activated carbon hosting functional germicidal ions, and (v) an air permeable non-woven membrane with adhesive edge. The said layers are compounded by pressing and coating to make a comprehensive multi-layer wound care dressing product.

Dressings for tissue treatment, which may comprise a first layer and a second layer. The first layer may comprise or consist essentially of a first plurality of perforations formed through the first layer and arranged in a first pattern of rows. Each of the first plurality of perforations may be parallel to a first direction. The first layer may comprise or consist essentially of a second plurality of perforations formed through the second layer and arranged in a second pattern of rows. Each of the second plurality of perforations may be parallel to a second direction. The first plurality of perforations and the second plurality of perforations may be configured to open in response to a pressure gradient across the first layer. A second layer may comprise or consist essentially of a manifold, and coupled to the first layer.

A reduced-pressure system for treating tissue, such as damaged subcutaneous tissue, includes a shaped dressing bolster for placing on the patient's epidermis and substantially sized to overlay the damaged subcutaneous tissue. The system further includes a sealing subsystem for providing a fluid seal over the shaped dressing bolster and a portion of the patient's epidermis, and a reduced-pressure subsystem for delivering a reduced pressure to the sealing subsystem. The reduced-pressure system may develop a force, which may include a vertical force that is realized at tissue site deeper than the epidermis or a closing force directed towards the incision. The shaped dressing bolster is shaped to evenly distribute the force. Other methods and systems are included.

A method of making a wound dressing comprising the steps of: providing an apertured substrate layer; coating the substrate layer with a fluid silicone prepolymer composition; thermally partially curing said silicone prepolymer composition to form a partially cured silicone coating on the substrate; laminating the coated substrate layer to a base layer to form a laminate having said partially cured silicone coating in contact with a surface of the base layer; followed by exposing the laminate to ionizing radiation, to further cure the partially cured silicone coating and to bond the silicone coating to said surface of the base layer. The radiation cure results in strong bonding between the siliconized substrate and incompatible base layers such as polyurethane foams. Also provided are wound dressings obtainable by the process of the invention.

A wound dressing system that includes a conformal cover and an infusion pump is provided. The cover includes a fluid port and an oxygen catalyst. The infusion pump is configured to deliver a bioactive liquid to the cover via the fluid port. The liquid includes an oxygen precursor. Upon combination, the oxygen catalyst and precursor react to form oxygen. A method of applying a wound dressing system including a bioactive powder, a bioactive liquid, and a conformal cover to a wound site is also provided. The method includes applying the powder to the wound site; securing the cover around the wound site, where the cover includes an oxygen catalyst and a fluid port; and delivering the bioactive liquid to at least an inner layer of the cover via the fluid port, where the bioactive liquid includes an oxygen precursor.

The invention relates to a process for producing a composite material for wound dressings, comprising the following steps: (I) providing a first film, having a first film surface and a second film surface running virtually parallel to the first film surface; (II) mixing an NCO-terminated polyurethane prepolymer with at least water to give a polyurethane prepolymer/water mixture, (III) applying the polyurethane prepolymer/water mixture to at least one part of the first film surface to form a layer, the layer having a first layer surface which is in contact with the first film via at least one part of the first film surface, and having a second layer surface which runs virtually parallel to the first layer surface; (IV) covering at least one part of the second layer surface with a further film,
wherein the bond strength between the first film and the layer and also between the layer and the further film is greater in each case than the tensile strain at break of the layer.

The invention further relates to a composite material produced by the process of the invention and also to a wound dressing comprising such a composite material and also to the use thereof in a wound dressing for improving the absorption of wound secretion and the distribution of secretion in the wound dressing.

Systems, methods, and apparatuses for treating a tissue site are described, In some embodiments, the system may include a pouch having an upstream layer, a downstream layer, and an absorbent member enclosed between the upstream layer and the downstream layer. The upstream layer and the downstream layer may each include a hydrophobic side and a hydrophilic side, The hydrophilic side of both the upstream layer and the downstream layer may be positioned facing the absorbent member. The hydrophobic side of both the upstream layer and the downstream layer may form a portion of an exterior surface of the pouch such that fluid incident on the pouch is distributed laterally along the exterior surface of the pouch before being absorbed by the absorbent member.

The present invention relates to a composition that can be used as or as part of a wound dressing and to wound dressings comprising the same. More specifically, the present invention relates to a composition that disrupts and kills bacteria within a biofilm and also prevents biofilm formation. The composition comprises a first component selected from the group consisting of chitosan, chitin, derivatives of chitosan, derivatives of chitin, and combinations thereof; at least one triprotic acid and at least one solubilising acid.

A system for treating a linear wound on a patient has a closing dressing bolster for placing on the patient's epidermis over the linear wound, a sealing subsystem for providing a seal over the closing dressing bolster and the patient, and a reduced-pressure subsystem for delivering reduced pressure to the sealing subsystem. The sealing subsystem and reduced pressure subsystem are operable to deliver reduced pressure to the closing dressing bolster. The closing dressing bolster is operable under reduced pressure to develop a inward closing. The closing dressing bolster may include one or more closing members on each side of a center wound area to create the inward closing when under reduced pressure. A compressive force may also be developed. Other systems and methods are presented.

A combination therapy pad that includes a first layer and a second layer operatively coupled to the first layer. A fiber-optic array is disposed between the first layer and the second layer. A third layer is operatively coupled to the first layer. The third layer includes a vacuum tube in fluid communication with a vacuum source and a therapeutic fluid tube in fluid communication with a therapeutic fluid source. The third layer provides at least one of vacuum therapy and therapeutic fluid treatment to a wound area.