Devices that may couple two or more apparatuses, such as an organ-on-a-chip device and a microfluidic device. Devices that include an organ-on-a-chip device, a microfluidic device, and a cap that couples the organ-on-a-chip device and the microfluidic device. Systems that include the devices and a detection unit. Methods for quantitation of insulin.

A method and device for detecting pyrethroid pesticide residues in crops. Reaction membrane is arranged on a bottom plate and provided with a check-up line and a quality control line; a first mounting block and a second mounting block are arranged on the bottom plate; a first slide is arranged in the first mounting block, a second slide is arranged in the second mounting block; a sample pad and a bonding pad are arranged in the first slide; a water absorption pad is arranged in the second slide; a liquid inlet provided with a pipe is formed in the first mounting block, a pressing hole provided with a press block is formed in the second mounting block; protrusions are respectively formed on the pipe and the press block; sliding grooves are formed in the liquid inlet and the pressing hole; and first springs are arranged between the protrusions and the sliding grooves.

Disclosed herein, inter alia, are compositions and methods of use thereof for interrogating a cell.

The present disclosure provides novel gravitational flow assays for detecting an antigen in a biological sample using DNA-capture sequences. Specifically, gravitational flow assays and methods of detecting viruses, including coronaviruses, are provided.

The present invention relates to a method for determining the distinctive nutritional requirements of a patient with specific nutritional needs and providing a composition meeting the distinctive nutritional requirements of said patient.

Provided herein are devices, methods and compositions useful in obtaining aptamers for biosensor probes. Such methods, devices and compositions are useful for novel clinical or companion drug diagnostic and personalized theranostic assays.

In some aspects, the present invention provides chimeric transferrin receptor (TfR) polynucleotides and polypeptides. In other aspects, this invention provides chimeric TfR transgenic animal models and methods of using the animal models to identify therapeutics that can cross the blood-brain barrier.

This technology relates in part to optical methods for analyzing particles, including nanoparticles, thereby determining their presence, identity, origin, size and/or number in a sample of interest.

The present disclosure relates to a lateral flow immunoassay device with an increased detection signal intensity by applying a pressure to a membrane, and the lateral flow immunoassay device manufactured by applying the pressure to the membrane according to the present disclosure shows significantly higher sensitivity than that of a lateral flow immunoassay device without applying a pressure to the membrane. Accordingly, the present disclosure, as an invention that increases the detection signal intensity by a very simple physical method without the need for chemical treatment, is suitable for mass production and may obtain an effect of reducing costs without requiring the use of additional materials. Therefore, the present disclosure can be usefully used for a lateral flow immunoassay device for detecting various target materials.

Disclosed are isothiocyanate (ITC)-detecting biosensors that utilize recombinant host cells containing an ITC responsive genetic element such as a saxA promoter, operably linked with a reporter element, such as a luxCDABE operon or ilux operon. Such biosensors can detect the presence of diverse ITCs in samples such as plant extracts, biofumigated soils and seed meal amended soils.