Dressings for use in negative pressure therapy and methods of making the dressings are provided herein. The dressings may comprise at least two layers in a stacked configuration. The first layer may comprise a manifold layer and the second layer may comprise a silicone gel layer. The second layer may have perforations to form fluid restrictions that can open and close when used in negative pressure therapy. The perforated second layer may be formed by a first and a second curing step.

A dressing for negative pressure wound therapy includes an absorbent layer comprising a gelling absorbent material for absorbing exudate, a peripheral adhesive skin contact layer comprising a hydrocolloid adhesive and defining a window through which the absorbent layer is able to contact a wound, and a cover layer that is water impermeable and air permeable. The cover layer defines an aperture to be used with a pump assembly to provide negative pressure to a wound site.

Disclosed herein is a device which is intended to deliver and maintain reduced pressure to body surfaces for application of reduced pressure wound therapy (RPWT) also known as negative pressure wound therapy (NPWT). During application of this type of therapy, a substantially airtight seal is formed around a section of tissue to be treated. This seal is formed by a dressing which provides fluid communication from a section of tissue to a reduced pressure source. Disclosed herein is a dressing system which is configured to enhance usability and functionality of this dressing. First, the system may be configured to allow full rotation of the fluid communication conduit to the reduced pressure source along the axis substantially normal to the dressing. Second, the system may be configured to include a one-way valve to prevent backflow of any drainage fluids. Third, the system may be configured with transparent windows covered by opaque flaps to allow inspection through the dressing. Fourth, the system may be configured to include an indicator which visually makes clear whether reduced pressure is being applied or not. Fifth, the system is configured to minimize the profile of the dressing system.

Herein is disclosed a composition comprising: a layer of water-swellable hydrogel, wherein the hydrogel has embedded therein a reinforcement sheet of liquid-water-permeable material, wherein the layer of hydrogel has a wound-facing side and a non-wound-facing side and apertures extend through the layer of hydrogel from the wound-facing side to the non-wound-facing side and through the reinforcement sheet, wherein the mean area of the apertures on at least one of the wound-facing side and non-wound-facing side of the hydrogel is at least 5 mm.sup.2.

A dressing for treating a tissue site with negative pressure may include a first layer having a first side, a second side, and fenestrations having a raised edge extending from the first side. The raised edge is configured to expand in response to a pressure gradient across the first layer. The dressing also includes a second layer adjacent to the first side. The second layer includes a manifold. The dressing also includes a cover coupled to the second layer opposite the first layer. The cover includes a polymer drape.

Dressings for tissue treatment with negative pressure and methods of using the dressings for tissue treatment with negative pressure, which may comprise a dressing having at least three layers assembled in a stacked relationship. The first layer may comprise or consist essentially of a polymer film having a plurality of fluid restrictions that are normally unstrained or closed. The second layer may comprise a manifold, and the third layer may comprise or consist essentially of a polymer drape. A fourth layer, which may be coupled to the first layer opposite the second layer, may comprise or consist essentially of a silicone gel having a plurality of apertures. In some examples, the plurality of apertures in the fourth layer may be registered with the fluid restrictions of the first layer.

An ostomy bag can include one or more sensors for measuring one or more metrics. An ostomy wafer can also include one or more sensors for measuring one or more metrics. The sensors can be temperature sensors and/or capacitive sensors, for example, and the metrics can include bag fill, leakage, skin irritation, and phase of stoma output, among others.

A method of healing a wound including contacting a wound edge with a tropoelastin or elastin derived peptide in conditions for enabling a sustained contact of the tropoelastin with the wound edge for a time period for enabling re-epithelialization of the wound.

Embodiments disclosed herein are directed to the treatment of wounds using negative pressure. Some embodiments disclosed herein provide for a hydrophilic drainage layer, which may be suitable for use in abdominal wound sites, and which may be sized in a dimensionally-independent manner. Additional embodiments provide for an organ protection layer, as well as a system for the treatment of abdominal wounds.

The present invention discloses a wound dressing, which includes a carrier, a dressing layer and an adhesive layer. The carrier includes a central portion, a plurality of fixed portions, and a plurality of slashes. The central portion has a geometric center. The fixed portions are disposed around the central portion, and the number of the fixed portions is between 3 and 20. Each of the slashes is located between two fixed portions. The carrier has a first length, and each of the slashes has a second length. The first length is the shortest distance from an outer edge of a fixed portion to the geometric center. The ratio of the second length to the first length is between 0.2 and 0.8. The dressing layer is disposed on the central portion and includes a hydrogel. The adhesive layer is disposed on the fixed portions.