Combined dissolution rate and permeation rate testing apparatus includes temperature-controllable testing cell units arranged on a housing frame. Each testing cell unit includes a donor chamber receivable of dissolution media, a receptor chamber receivable of bodily fluid, gaskets that retain a membrane between the two chambers, and controllable mixers that mix the fluid in the receptor chamber. A flow control arrangement operatively circulates dissolution media through the donor chamber and enables sampling of the dissolution media. Another flow control arrangement operatively circulates bodily fluid through the receptor chamber. An analysis unit analyzes dissolution media removed from the donor chamber and bodily fluid removed from the receptor chamber to provide data about dissolution of a pharmaceutical product dissolved in the dissolution media and permeation of the pharmaceutical product through the membrane into the bodily fluid.

An automatic analyzer achieves both restraining unnecessary usage of a consumable supply and reducing burdens on an operator in a re-execution processing in a case where pipe functions are suspended/stopped, and is capable of completely efficiently performing an analysis preparation processing or an analysis terminating processing. In the automatic analyzer, a storage unit stores information on pipe functions, and information on re-execution setting for setting a re-execution maintenance item from which re-execution is started with respect to a suspended maintenance item if pipe functions of a plurality of maintenance items are suspended halfway, and a computer sequentially executes the plurality of maintenance items, based on the information on pipe functions, and re-executes maintenance from the re-execution maintenance item associated with a suspended maintenance item, based on the suspended maintenance item and the information on re-execution setting, if the pipe functions of the plurality of maintenance items are suspended halfway.

A method of operating a tissue processor for processing tissue samples. The tissue processor includes at least one retort for receiving tissue samples, at least one container for storing a reagent, and at least one sensor arranged for fluid communication with one or both of the at least one container and the at least one retort for measuring a measured purity level of a reagent. The method includes conducting reagent from the at least one container or the at least one retort to the at least one sensor, automatically measuring a measured purity level of the reagent, checking whether the measured purity level meets a predetermined purity level of the reagent associated with the at least one container, and thereby automatically determining whether the reagent is suitable for processing tissue samples in the tissue processor. Also, a tissue processor for processing tissue samples and a container for storing tissue samples.

An apparatus and a method for indicating a reagent status in a reagent bottle in a tissue processor and a tissue processor are provided. The apparatus includes a detector, a controller, and an indicator. The detector is configured to detect the reagent status. The controller is configured to generate a control signal based on the reagent status. The indicator is configured to generate a signal for indicating the reagent status based on the control signal. The apparatus may intuitively indicate the reagent status for an operator, such that the operator may replace the reagent timely and accurately, avoiding reagent replacement error.

A test apparatus for measuring the temperature of a reactor using a thermochromic pigment, and a method for controlling the test apparatus are disclosed, based on a technology for irradiating light of different wavelengths on a thermochromic pigment accommodated in a reactor and estimating temperature of the reactor using a difference between absorbance values corresponding to the light of the different wavelengths. The test apparatus includes at least one light emitter configured to irradiate light of different wavelengths onto a chamber included in the reactor, a light receiver configured to receive the light that propagates through the chamber, and a controller configured to measure absorbance values of the thermochromic pigment in correspondence to the different wavelengths of the light, to calculate a difference between the measured absorbance values, and to determine a temperature of the reactor in correspondence to the calculated difference between the absorbance values.

In an automatic analyzing apparatus that analyzes a mixture of a tested sample and a reagent, by selecting the reagent, acquiring cross-check information unique to the kind of the selected reagent, inputting input information for acquiring permission for input of data including an analysis parameter of the selected reagent, and cross-checking the cross-check information and the input information, it is determined whether to permit the input of the data. In a case that it is determined to permit the input of the data, the input of the data is accepted and, based on the analysis parameter reflecting the inputted data, the mixture of the tested sample and the reagent is measured and analysis data is generated.

The present invention relates to systems and methods of determining quality compliance for a set of biological sample testing devices used with one or more test instruments at the point-of-care in a hospital or other location that delivers medical care. In particular, the systems and methods ensure that only biological sample testing devices that pass a quality assurance protocol are used for point-of-care testing.

Methods and systems for ordering assays which detect SNPs or gene expression are provided. The methods use PCR and RT-PCR procedures. Collections of stock assays are assembled using pre- and post-manufacturing quality control procedures and made available to consumers via the Internet. In addition, custom assays are prepared upon order from the consumer and these assays are also prepared using pre- and post-manufacturing quality control procedures. The assays are then delivered to the consumer.

In an example of an embodiment, a first sample set is prepared that includes a test sample prepared from a first subject sample and a reagent, and at least one control sample prepared from at least one of a positive control and a negative control, and a second sample set is prepared that includes a test sample prepared from a second subject sample and a reagent and does not contain at least one of the control samples contained in the first sample set. The nucleic acid amplification in the first sample set is measured in the first unit, the nucleic acid amplification in the second sample set is measured in the second unit, and the measurement result of each test sample contained in the first sample set and second sample set is analyzed based on the measurement result of the control sample contained in at least the first sample set.

An automatic analysis device includes a processing unit 3 which performs the treatment on a specimen before analysis of the specimen, supply equipment which supplies a reagent to a reaction vessel 11 disposed in the processing unit 3, a liquid temperature adjusting unit 1 which adjusts a temperature of the reagent supplied to the reaction vessel 11 by the supply equipment, a control unit 201, and a first temperature detection unit 4 which detects at least one temperature of a temperature of the air within the processing unit 3 and a temperature of the reagent supplied to the reaction vessel 11, in which the liquid temperature adjusting unit 1 and the control unit 201 execute temperature adjustment of the reagent based on a first temperature detected by the first temperature detection unit 4.