Provided is a technique related to an automatic analyzer and capable of ensuring cleaning performance of a reaction container by a cleaning process including a tip suction step, and preventing decrease in analysis accuracy or improving the analysis accuracy. The automatic analyzer includes a control apparatus, a block suction mechanism that moves a suction nozzle and a suction block for suctioning a liquid in the reaction container up and down and suctions the liquid, and a block cleaning mechanism for cleaning the suction block. After receiving an analysis request, the control apparatus causes, in a tip suction step that is provided before an analysis step and is a last step of a cleaning step, both suction of the liquid by the block suction mechanism and cleaning of the suction block by the block cleaning mechanism to be performed in a first step, and then only the suction of the liquid by the block suction mechanism to be performed in a second step including one or more cycles; and causes the analysis step to be performed using the reaction container in which the second step is performed.

A system for separating an analyte from other components of a sample includes a receptacle holding station and a magnetic separation station. The receptacle holding station includes one or more stationary, permanent magnets positioned to apply a magnetic field to the contents of a receptacle held stationary within the receptacle holding station. The magnetic separation station includes one or more permanent magnets and is configured to perform a magnetic separation procedure on the contents of a receptacle transported from the receptacle holding station to the magnetic separation station. The magnetic separation procedure includes isolating an analyte immobilized on a magnetically-responsive solid support within the receptacle and removing other components of the sample from the receptacle. The magnetic separation station is configured to provide relative movement between the receptacle and the one or more permanent magnets after the receptacle is transported to the magnetic separation station.

Provided is an automated analysis device with which sufficient reaction process data can be acquired irrespective of the scale of the device, and with which it is possible to ensure freedom of the device configuration. An automated analysis device 100 is provided with: a reaction disk 1 which circumferentially accommodates a plurality of reaction vessels 2; a specimen dispensing mechanism 11 which dispenses a specimen into the reaction vessels 2; a reagent dispensing mechanism 7 which dispenses a reagent into the reaction vessels 2; a measuring unit 4 which measures a reaction process of a mixture of the specimen and the reagent in the reaction vessels 2; and a cleaning mechanism 3 which cleans the reaction vessels 2 after measurement. Further, the automated analysis device 100 includes a controller 21 which controls the drive of the reaction disk 1 such that in one cycle the reaction vessels 2 move by an amount A in the circumferential direction in such a way that N and A are mutually prime, B and C are mutually prime, and the relationship AB=NC1 holds, where N is the total number of reaction vessels 2 accommodated in the reaction disk 1, the reaction disk 1 moves through C (where C>1) rotations+an amount equivalent to one reaction vessel after B (where B>2) cycles, and the number of reaction vessels 2 moved in one cycle is A (where N>A>N/B+1).

An analysis method irradiates, with laser light, an analysis substrate made of a resin material and having a reaction region on which detection target substances and nanoparticles of a metal compound for labeling the detection target substances are captured. The analysis method extracts, as a substrate signal level, a signal level generated when receiving reflected light from the analysis substrate. The analysis method receives reflected light from the reaction region to generate a light reception level signal. The analysis method extracts a nanoparticle detection signal from the light reception level signal of the reflected light from the reaction region, the nanoparticle detection signal having a higher level than the signal level of the reflected light from the analysis substrate. The analysis method detects the nanoparticles in accordance with the extracted nanoparticle detection signal.

A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, and a loading mechanism with a beam for loading and unloading the centrifuge with the at least one reaction vessel unit.

A centrifuge for cleaning a reaction vessel unit, having a rotor for holding at least one reaction vessel unit with its opening(s) directed outwardly, a motor for rotating the rotor around a rotation axis, a housing having a substantially cylindrical inner surface, wherein a drain is provided for discharging fluid expelled from the reaction vessel unit, wherein a gap is provided between the inner surface and the rotor so that by rotating the rotor a wind is generated which drives the expelled fluid on the inner surface to the drain wherein an aspiration pump is connected to the drain for discharging fluid.

The automatic analyzer according to the present invention includes an avoidance information storage unit configured to store avoidance information including a condition requiring carryover avoidance for the pretreatment container, an avoidance determination unit configured to determine whether or not the avoidance is necessary, based on information of samples dispensed before and after to the pretreatment container in which the sample dispensing nozzle is to dispense the sample, and the avoidance information to generate a command, and an avoidance control unit configured to control the sample dispensing nozzle so that the sample dispensing nozzle defers the dispensing of the sample to the pretreatment container, based on the avoidance command from the avoidance determination unit.

Provided are a device and a cleaning mechanism for a reaction container in the device that are characterized by being provided with: a reaction disk for holding a reaction container; a sample dispensing mechanism for dispensing a sample to the reaction container; a reagent dispensing mechanism for dispensing a reagent to the reaction container; an optical system comprising a light source for applying light to a mixture of the sample and the reagent dispensed to the reaction container, and a detector for detecting the light applied from the light source; and a cleaning mechanism for cleaning the reaction container, wherein the cleaning mechanism is provided with a cleaning liquid supply nozzle for supplying a cleaning liquid to the reaction container after an analysis, a cleaning liquid suction nozzle for suctioning the supplied cleaning liquid, and a cleaning tip provided on the lower end of the cleaning liquid suction nozzle, and the side surface of the cleaning tip is formed such that the width of the cleaning tip becomes smaller downward, in the state where the cleaning tip is inserted into the reaction container, in at least a surface opposing the light source and a surface opposing the detector, and in a range that overlaps with a photometric range in which light applied to the reaction container from the light source passes through the reaction container toward the detector or in a range that is larger than the photometric range.

A high-throughput automatic analyzer integrates a biochemical analysis section and a blood coagulation analysis section. The analyzer is capable of achieving a reduction in size, system cost, and lifecycle cost. The automatic analyzer includes: a reaction disk; a first reagent dispensing mechanism that dispenses a reagent to reaction cells on the reaction disk; a photometer that irradiates a reaction solution in the reaction cell with light; a reaction cell cleaning mechanism; a reaction vessel supply unit that supplies a disposable reaction vessel for mixing and reacting a sample and a reagent with each other; a second reagent dispensing mechanism that dispenses a reagent to the disposable reaction vessel; a blood coagulation time measuring section that irradiates a reaction solution in the disposable reaction vessel with light to detect transmitted or scattered light; and a sample dispensing mechanism that dispenses a sample to the reaction cell and the disposable reaction vessel.

The automatic analyzer includes a storage unit storing the reaction containers of cleaning target by day unit in such a manner that all the reaction containers mounted on a reaction disk are to be cleaning target within a plurality of days, and a control unit exerts a control in such a manner that during an operation state after the sample of analysis object is dispensed to the reaction containers, a sample of analysis object in each of the reaction containers is analyzed, and not the sample but a detergent is dispensed to the reaction containers of cleaning target of an appointed day, the reaction containers of cleaning target of the appointed day being stored in the storage unit, to soak and wash the reaction containers for a certain time.