G01N2035/0441

DEVICES, METHODS, AND SYSTEMS TO COLLECT, STORE, AND ANALYZE CHEMICAL SUBSTANCES

Detection devices, systems, and methods include those for detecting analytes (e.g., volatile organic compounds (VOCs) and/or other chemical substances) from a target area of a subject's anatomy (e.g., a subject's skin, a wound on a subject, etc.). In some cases, a detector may have a detecting component that includes an analyte sensitive material applied to a substrate. The detector may be used with a pump. The detector may include a hydrophobic, gas permeable material configured to limit liquid reaching the analyte sensitive material, while allowing analytes in gaseous fluid to reach the analyte sensitive material.

Apparatus and method for a lysis of a sample, in particular for an automated and/or controlled lysis of a sample
11447737 · 2022-09-20 · ·

The present invention provides an apparatus and a method for a lysis procedure, in particular for an automated and/or controlled lysis procedure of a sample, in particular a biological sample. The apparatus comprises at least one rotation disc (31), at least one vial holder (90) which is configured to receive a vial (100), wherein the vial holder (90) is arranged on the disc (31), at least one driving device (20) which is configured to rotate the disc (31) and the vial holder (90), at least one heating device (60) which is configured to heat the sample to a determined incubation temperature, and—at least one control device (70) which is configured to control the driving device (20) and/or the heating device (60) by means of a timing and/or step control, and/or—at least one transmitting device (80) for inductive coupling for energy and signal transmission, which is configured to transmit the energy for heating to the heating device (60), and/or—wherein the driving device (20) is configured to rotate the disc (31) in a first direction (A1) and/or with a first speed, and to rotate the vial holder (90) in a second direction (A3) and/or with a second speed. The apparatus and the method are adapted for an (automated) lysis procedure, wherein the lysis can be carried out in a safe, efficient and effective manner.

Controlling method of preprocessing apparatus

A preprocessing apparatus uses preprocessing kits prepared for samples, respectively, sets the preprocessing kits in plural processing ports provided so as to correspond to preprocessing items, and executes a predetermined preprocessing item. A controller which controls operations of a carrying mechanism holding and carrying the preprocessing kits, and processing parts executing the preprocessing items in the respective processing ports, includes a processing-state control part, a random access part, and a preprocessing part. The random access part is configured to check availability of a preprocessing port corresponding to a preprocessing item to be executed on a sample contained in a preprocessing kit, and set the preprocessing kit in a processing port if the processing port is available as a processing port corresponding to the preprocessing item. The preprocessing part executes a corresponding preprocessing item on a sample in a preprocessing kit when the preprocessing kit is set in the processing port.

SAMPLE ROTATING RACK AND RAMAN SPECTRUM DETECTOR
20220221406 · 2022-07-14 ·

A sample rotating rack and a Raman spectrum detector. The sample rotating rack comprises a rotating body (1) and a plurality of sample carriers provided thereon. The plurality of sample carriers are distributed around the circumference of the rotating body (1) and can be irradiated by light rays located at the periphery of the rotating body (1). The sample rotating rack is provided with as many sample carriers as possible in a space as small as possible, and optical irradiation can be quickly conducted on a plurality of samples by rotating the rotating body (1). The Raman spectrum detector comprises a laser (6), a spectrum analyzer (7), a Raman probe (10), a rotating table (8) and a sample rotating rack; the sample rotating rack is arranged on the rotating table (8), the Raman probe (10) is arranged at the periphery of the sample rotating rack, and the Raman probe (10) is electrically connected to the laser (6) and the spectrum analyzer (7) respectively; and the laser (6) is used for emitting excitation light by means of the Raman probe (10), and the Raman probe (10) can receive Raman scattered light and return same to the spectrum analyzer (7). The Raman spectrum detector can rapidly perform optical analysis and test on a plurality of samples, and the operation is simple and the test efficiency is high.

Preprocessing apparatus and analysis system comprising the preprocessing apparatus
11385206 · 2022-07-12 · ·

Disclosed herein is a preprocessing apparatus that makes it possible to highly efficiently analyze specimens held by solid media, such as dried blood spots to be used for newborn mass screening or the like. The preprocessing apparatus includes: a preprocessing container setting part in which a preprocessing container containing a solid sample including a specimen to be analyzed and a solid medium holding the specimen is to be set; a carrying mechanism that carries the preprocessing container set in the preprocessing container setting part; and a preprocessing part that has a port for setting the preprocessing container carried by the carrying mechanism and that is configured to perform preprocessing including extraction processing for extracting the specimen from the solid sample contained in the preprocessing container set in the port.

Pretreatment method for specimen held in microchannel, pretreatment apparatus for performing pretreat method, and analysis system provided with pretreatment apparatus
11385251 · 2022-07-12 · ·

A pretreatment apparatus includes a pretreatment container placement section where a pretreatment container which is housing a specimen holding member including a microchannel for holding a specimen is placed; a carrying mechanism for carrying the pretreatment container that is placed at the pretreatment container placement section; and a pretreatment section including a port where the pretreatment container that is carried by the carrying mechanism is placed, the pretreatment section being configured to perform pretreatment including a shaking process of shaking the pretreatment container to extract the specimen from the specimen holding member in the pretreatment container that is placed in the port.

SAMPLE HANDLING SYSTEMS, MASS SPECTROMETERS AND RELATED METHODS
20220084803 · 2022-03-17 ·

Slide analysis a gripper with three sensors for controlling a slide grip sequence and at least one rotatable carousel with a slide receiving channel. The systems also include a robot with a robot arm that holds a slide gripper residing inside the housing in communication with the rotatable carousel. The systems also include a load lock chamber and a door sealably coupled to the second end portion and an acquisition vacuum chamber with an X-Y stage and a slide holder with a vacuum seal.

VIAL AUTOLOADER

An autoloader is disclosed for staging samples in vials to be loaded automatically into an analyzer such as a moisture analyzer for moisture analysis. The analyzer uses vials to hold small amounts of sample materials. The autoloader holds the vials in a horizontal orientation for delivery to and removal from the analyzer.

On-axis, angled, rotator for x-ray irradiation

An on-axis, angled, rotator device is disclosed. The rotator device may include a container containing a slot for receiving a sample. An angle of the slot may be configured to be between 0 and 180 degrees relative to a perpendicular irradiation plane of a radiation device. The rotator device may include a cup positioned within an opening of the container. Additionally, the rotator device may include a driveshaft configured to transmit torque to cause the cup to be rotated when the cup is positioned within the opening. When the sample resides within the slot and the driveshaft transmits the torque to the cup, the cup may cause the sample to rotate about a center axis of the sample. The angle of the slot containing the sample and the rotation of the sample about the center axis may facilitate uniform radiation exposure to the sample when the radiation device emits radiation.

AUTOMATIC ANALYZER AND CLEANING METHOD

An automatic analyzer includes a cleaning pool, a discharge port, a waste fluid pipe, a valve, and a guiding unit. The cleaning pool is used to clean a predetermined member with a fluid. The discharge port discharges the fluid. The waste fluid pipe connects the cleaning pool and the discharge port. The valve is disposed to the waste fluid pipe. The guiding unit guides a cleaning fluid to the cleaning pool via the waste fluid pipe.