The present invention relates to the technical field of sensor calibration, particularly a calibration system and a calibration method for NDIR gas sensors. The calibration system comprises: a client-server computer network with calibration software, a relay module, a gas source group, a mass flow controller, a high and low temperature chamber, a gas analyzer, and a calibration tooling rack group for implementing broadcasting-style calibration. The calibration method consists of: a Lambert-Beer weighted concentration calculation mode combined with an adaptive piecewise linear temperature compensation mode. Integrating the calibration system and the calibration method can effectively streamline the calibration process, improve the calibration accuracy, and reduce the calibration time and cost of the NDIR gas sensors. It can, therefore, conveniently realize a simultaneous calibration of many NDIR gas sensors for mass production and enable a greener production environment with a higher degree of carbon neutrality.

Disclosed herein are scientific instrument support systems, as well as related methods, computing devices, and computer-readable media. For example, in some embodiments, a method of supporting spectroscopic calibration may include: generating a base calibration model using data from multiple base spectroscopic instruments, and finetuning the base calibration model using data from a target spectroscopic instrument to generate a target calibration model for use with the target spectroscopic instrument. In some embodiments, the number of wavelengths used in generating the base calibration model and/or the target calibration model may be less than the total number of wavelengths represented in the output of the spectroscopic instruments.

Method is presented for monitoring time-varying fluorescence. The method includes providing a measurement data set, transforming each Flr signal of each measurement data entry of the measurement data set to an agent intrinsic fluorescent (IF) signal, monitoring the agent IF signal for each measurement data entry within the measurement data set, whereby fluorescence emission of the agent is determined with reduced sensitivity to the time-varying optical properties of the medium.