Provided is a method of manufacturing a skin attachable thin film coated with a functional mixture, the method including: preparing a microstructured thin film including a base thin film and at least one microstructure protruding from the base thin film; and coating a functional mixture on the microstructure excluding a region of the base thin film in which the microstructure is not formed, wherein in the coating the mixture, the functional mixture is irregularly coated on the at least one microstructure.

A method of applying a patterned coating of a silicone adhesive to a substrate sheet, comprising the steps of pattern coating a silicone precursor composition onto the substrate, followed by thermally curing the precursor composition coated on the substrate. The precursor composition is a viscous fluid, and the pattern coating is performed by suitably modified block printing, intaglio printing or screen printing methods. Also provided are coated substrates obtainable by the methods of the invention, and wound dressings comprising such coated substrates.

A hydrocolloid-based skin patch that includes ozonated olive oil absorbed within a hydrocolloid layer, and a release layer overlying one side of the hydrocolloid layer.

Systems and methods for customizing medical tapes from a roll stock at customer use sites are provided. The system includes a tape converting machine where an adhesion modification mechanism is configured to modify adhesion properties of the tape from the roll stock, automatically or based on received customization instructions.

A dressing for treating tissue may be a composite of dressing layers, including a contact layer, a manifold layer, and an adhesive drape. The manifold layer may include one or more layers of felted open-cell foam in some examples. The manifold layer may be relatively thin to reduce the dressing profile and increase flexibility, which can enable it to conform to difficult geometry and other tissue sites under negative pressure. The dressing may have a length and a width less than the length. The manifold layer may include a population of holes extending at least partially therethrough, wherein the holes may be configured to promote anisotropic contraction of the dressing parallel to its width. The population of holes may have a circular, ovoid, triangular, square, hexagonal, irregular, or morphous shape. The dressing may be a bolster that may anisotropically contract to provide a closing force to a linear wound.

The present invention falls within the area of polymeric materials based on ultrafine fibres for use in the pharmaceutical, nutraceutical and cosmetic sector, relating to the method of producing self-adhesive patches and the use thereof as a platform for the controlled release of bioactives by electrohydrodynamic and/or aerohydrodynamic processing techniques.