Sealing members and methods of manufacturing the same are described. A first film layer and a second film layer each having a first side and a second side can be provided. A first adhesive can be coupled to the second side of the first film layer to form a first adhesive layer. A second adhesive can be coupled to the second side of the second film layer to form a second adhesive layer, and a third adhesive can be coupled to the first side of the second film layer to form a third adhesive layer. One or more perforations can be formed through the third adhesive layer, the second film layer, and the second adhesive layer. A first side of the third adhesive layer can be coupled to a second side of the first adhesive layer.

Systems and methods for component stress relief are disclosed. In some embodiments, a wound dressing includes a substantially stretchable wound contact layer including a wound facing side and a non-wound facing side. The wound facing side or the non-wound facing side of the wound contact layer can support a plurality of electronic components and a plurality of electronic connections that connect at least some of the plurality of the electronic components. The wound facing side or the non-wound facing side of the wound contact layer can include a region of substantially non-stretchable material that supports at least one electronic component from the plurality of electronic components. The at least one electronic component can be attached to the wound contact layer with adhesive material. Such arrangement can securely position the at least one electronic component and limit the mechanical strain on the at least one electronic component supported by the region.

Scalable virtual memory metadata management comprising a plurality of pre-instantiated VM metadata containers representing the entire amount of real physical memory available to a computing system, with additional instantiated VM metadata containers created as needed. Individual and/or groups of VM metadata containers are assigned to metadata container groups, wherein each container group is controlled by an acquired lock assigned to the VM metadata container groups. Virtual memory metadata is managed using a “least used” technique. In response to allocation requests, the allocator scans the container groups/VM containers and fulfills memory object metadata allocation to the least used VM metadata container of the least used container group, filling the individual VM metadata containers and/or the container groups at a nearly equal rate.

A system for treating a tissue site includes a pressure source to apply reduced pressure, and a manifold in fluid communication with the pressure source to provide reduced pressure to the tissue site. The system includes a drape for adhering to the tissue site to cover the tissue site and the manifold. The drape has a film layer having a thickness less than about 15 microns, and an adhesive coupled to the film layer. The adhesive seals the film layer to the tissue site to create a sealed space having the manifold therein. The adhesive is sufficiently thick to limit leaks between the film layer and the tissue site.

Carefully coordinated patches having camouflaging and/or benefit properties can be formed for application to a desired region of human skin. The patches include a flexible film having a first, adhesive, outwardly facing major surface and a second outwardly facing surface which is textured to correspond to skin covered by the patch during use; wherein the flexible film further comprises at least one pigmented region and at least one region adapted to modify one or more optical properties selected from the group consisting of light transmission, light reflection, and light absorption. Methods of custom use of such patches may include 3D printing processes.

A percutaneous absorption agent delivery device with: a solvent-impermeable cover film that has a first layer and a second layer, which are integrally continuous via a first fold and are superimposed, a non-seal region and a seal region are formed between the first layer and the second layer, the non-seal region disposed along the first fold, the seal region to surround the outer peripheral section of the non-seal region except for the section along the first fold, and an endless cut portion forming the non-seal region formed in the cover film; a percutaneous absorption agent carrying member is disposed in the non-seal region between the first layer and the second layer, and fixed to the cover film on the inner side of the cut portion; and an adhesive sheet that is detachably affixed to the outer surface of the cover film.

The present invention relates to a biocompatible, foldable, thin profile, low mass and high surface area, chitosan dressing, optionally modified with catechol, and suitable for treating bleeding in a physiological environment, e.g. gastrointestinal tract. The characteristics and structures of the chitosan dressing are provided. Methods of making and using the chitosan dressing are also provided.

Dressings for tissue treatment with negative pressure and methods of assembling the dressings for tissue treatment with negative pressure are disclosed. A method of assembling a dressing, which may comprise at least three layers assembled in a stacked relationship, may comprise providing an assembly station having at least one retaining pin, placing a first layer on the assembly station, placing a second layer on the assembly station, and bonding the second layer to the first layer. The first layer may comprise a plurality of apertures, at least some of which may be engaged by the retaining pins, and the second layer may comprise fluid restrictions and alignment areas for engaging with the retaining pins so that the fluid restrictions may be aligned with the apertures of the third layer.

Bandage apparatus, methods, and antimicrobial bandages for facilitating wound healing by providing an antimicrobial functionality. A bandage apparatus includes a substrate with a first surface and a second surface opposing the first surface. An attachment mechanism and a nanostructure film are provided on the first surface. The attachment mechanism facilitates removably attaching the substrate to a part of a body comprising a wound. The nanostructure film includes a plurality of nanostructures that contact the wound without puncturing the wound when the substrate is attached to the part of the body comprising the wound.

A medical drape for use with a reduced pressure system for providing reduced pressure to a tissue site is described. In some embodiments, the drape may include a flexible film, and an adhesive layer coupled to the flexible film. The adhesive layer may include a first adhesive disposed on a first portion of the flexible film in a first pattern. The first adhesive can be configured to secure the flexible film proximate to the tissue site. The adhesive layer generally includes a second adhesive disposed on a second portion of the flexible film in a second pattern. The second adhesive can be configured to seal the flexible film proximate to the tissue site. The first pattern and the second pattern are preferably registered so that the first portion and the second portion are offset to cover substantially different portions of the flexible film.